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The Impact of Probiotic Supplementation on Weight and Body Composition in Older Adults: A Systematic Review Publisher



Hoseinitavassol Z1 ; Ejtahed HS1, 2 ; Mansourzadeh MJ3 ; Ettehadmarvasti F1 ; Bahramali G4 ; Khalagi K1, 3 ; Hasaniranjbar S1 ; Siadat SD5 ; Nabipour I6 ; Ostovar A3, 7 ; Larijani B2
Authors
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Authors Affiliations
  1. 1. Obesity and Eating Habits Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, 1417653761, Iran
  2. 2. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, 1417653761, Iran
  3. 3. Osteoporosis Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, 1417653761, Iran
  4. 4. Department of Hepatitis and AIDS and Blood Borne Diseases, Pasteur Institute of Iran, Tehran, 1316943551, Iran
  5. 5. Microbiology Research Center, Pasteur Institute of Iran, Tehran, 1316943551, Iran
  6. 6. The Persian Gulf Marine Biotechnology Research Center, The Persian Gulf Biomedical Sciences Research Institute, Bushehr University of Medical Sciences, Bushehr, 7514633341, Iran
  7. 7. Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, 1417653761, Iran

Source: Journal of Biological Regulators and Homeostatic Agents Published:2024


Abstract

Background: Obesity as a complex disease significantly impacts life quality and expectancy in older adults. Managing obesity in older adults is particularly challenging. The use of probiotics has been recommended as a potential strategy for weight management. So, this study aims to review the effectiveness of probiotics on weight and body composition in older adults. Methods: A systematic search was conducted across multiple databases including PubMed, Web of Science, Scopus, and Embase, to retrieve relevant publications up to May 2023. Eligibility criteria were applied to select clinical trials that reported the effects of probiotics on weight and body composition in older adults. Two independent investigators performed data extraction according to a pre-designed table and assessed the quality of the selected studies using the Cochrane risk-of-bias tool. Results: A total of 705 records were found, and 12 articles were considered for the review. In four studies, the use of probiotics has been demonstrated to decrease on weight and body composition in older adults. However, due to the high diversity of bacterial species and multispecies probiotics used, it cannot be concluded which type of probiotics is recommended for managing obesity in older adults. Conclusions: While there is evidence suggesting that probiotics may have an impact on weight management, the effectiveness of probiotics on obesity in older adults is a more complex issue and influenced by various factors like aging, underlying diseases and lifestyle. More clinical studies are needed to determine the effective combination of probiotics for managing obesity in older adults. © 2024 The Author(s). Published by Biolife Sas. This is an open access article under the CC BY 4.0 license. Note: J. Biol. Regul. Homeost. Agents. stays neutral with regard to jurisdictional claims in published maps and institutional affiliations.
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