Administration of Dietary Antioxidants for Patients With Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials

Administration of Dietary Antioxidants for Patients With Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials Publisher Pubmed

Shahinfar H^{1, 2} ; Payandeh N^{2, 3} ; Elhamkia M^{2, 3} ; Abbasi F^{2, 4} ; Alaghi A^{2, 5} ; Djafari F^{2, 3} ; Eslahi M^{2, 6} ; Gohari NSF^{2, 7} ; Ghorbaninejad P^{2, 3} ; Hasanzadeh M^{2, 3} ; Jafari A^{2, 3} ; Jibril AT^{2, 3} ; Khorasaniha R^{2, 3} ; Mansouri E^{2, 3} Show All Authors

Shahinfar H^{1, 2}
Payandeh N^{2, 3}
Elhamkia M^{2, 3}
Abbasi F^{2, 4}
Alaghi A^{2, 5}
Djafari F^{2, 3}
Eslahi M^{2, 6}
Gohari NSF^{2, 7}
Ghorbaninejad P^{2, 3}
Hasanzadeh M^{2, 3}
Jafari A^{2, 3}
Jibril AT^{2, 3}
Khorasaniha R^{2, 3}
Mansouri E^{2, 3}
Monfared V^{2, 8}
Rezaee S^{2, 3}
Salehian A^{2, 8}
Shahavandi M^{2, 3}
Sheikhi L^{2, 9}
Milajerdi A^{2, 6}

Source: Complementary Therapies in Medicine Published:2021

Abstract

Objective: Accumulating evidence has been reported regarding the effect of dietary antioxidants on clinical variables in IBD patients, however, findings are controversial. This systematic review and meta-analysis aimed to investigate effect of dietary antioxidants on clinical variables in patients with IBD or its subtypes. Methods: We searched PubMed, Scopus, and ISI Web of Science from inception to January 2021 using relevant keywords. Data were pooled by using the random-effect model. All statistical analyses were done using STATA version 14. Results: Our meta-analysis was exclusively done on studies about the effect of curcumin on IBD patients, because limited studies were done on other antioxidants. Curcumin administration resulted in significant increment of clinical remission in patients with IBD (SMD: 0.86%, 95% CI: 0.16, 1.56, p = 0.016), significant remission in clinical symptoms (SMD: −0.96 score, 95% CI: −1.34, −0.57, p < 0.001), and significant increment in endoscopic remission in IBD patients (SMD: 0.51%, 95% CI: 0.16, 0.85, p = 0.004), comparing to control group. Curcumin supplementation also made better clinical response than control group (SMD: 0.74%, 95% CI: 0.22, 1.26, p = 0.005) and also resulted in significant improvement in quality of life of patients with IBD, as compared to control group (SMD: 1.23 score, 95% CI: 0.72, 1.74, p < 0.001). Conclusions: Our meta-analysis showed that curcumin significantly improved clinical and endoscopic remissions in IBD patients. This supplementation also caused significant reduction in clinical symptoms of IBD patients along with better clinical response and the increased quality of life. Further researches with larger sample size and longer period of intervention are required to evaluate efficacy of dietary antioxidants on clinical variables in patients with IBD. © 2021

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Style	Citing Format
MLA	Shahinfar H, et al.. "Administration of Dietary Antioxidants for Patients With Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials." Complementary Therapies in Medicine, vol. 63, no. , 2021, pp. -.
APA	Shahinfar H, Payandeh N, Elhamkia M, Abbasi F, Alaghi A, Djafari F, Eslahi M, Gohari NSF, Ghorbaninejad P, Hasanzadeh M, Jafari A, Jibril AT, Khorasaniha R, Mansouri E, Monfared V, Rezaee S, Salehian A, Shahavandi M, Sheikhi L, Milajerdi A (2021). Administration of Dietary Antioxidants for Patients With Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials. Complementary Therapies in Medicine, 63(), -.
Chicago	Shahinfar H, Payandeh N, Elhamkia M, Abbasi F, Alaghi A, Djafari F, Eslahi M, et al.. "Administration of Dietary Antioxidants for Patients With Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials." Complementary Therapies in Medicine 63, no. (2021): -.
Harvard	Shahinfar H et al. (2021) 'Administration of Dietary Antioxidants for Patients With Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials', Complementary Therapies in Medicine, 63(), pp. -.
Vancouver	Shahinfar H, Payandeh N, Elhamkia M, Abbasi F, Alaghi A, Djafari F, et al.. Administration of Dietary Antioxidants for Patients With Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials. Complementary Therapies in Medicine. 2021;63():-.
BibTex	@article{ author = {Shahinfar H and Payandeh N and Elhamkia M and Abbasi F and Alaghi A and Djafari F and Eslahi M and Gohari NSF and Ghorbaninejad P and Hasanzadeh M and Jafari A and Jibril AT and Khorasaniha R and Mansouri E and Monfared V and Rezaee S and Salehian A and Shahavandi M and Sheikhi L and Milajerdi A}, title = {Administration of Dietary Antioxidants for Patients With Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials}, journal = {Complementary Therapies in Medicine}, volume = {63}, number = {}, pages = {-}, year = {2021} }
RIS	TY - JOUR AU - Shahinfar H AU - Payandeh N AU - Elhamkia M AU - Abbasi F AU - Alaghi A AU - Djafari F AU - Eslahi M AU - Gohari NSF AU - Ghorbaninejad P AU - Hasanzadeh M AU - Jafari A AU - Jibril AT AU - Khorasaniha R AU - Mansouri E AU - Monfared V AU - Rezaee S AU - Salehian A AU - Shahavandi M AU - Sheikhi L AU - Milajerdi A TI - Administration of Dietary Antioxidants for Patients With Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials JO - Complementary Therapies in Medicine VL - 63 IS - SP - EP - PY - 2021 ER -

Style

Citing Format

MLA

Shahinfar H, et al.. "Administration of Dietary Antioxidants for Patients With Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials." Complementary Therapies in Medicine, vol. 63, no. , 2021, pp. -.

APA

Shahinfar H, Payandeh N, Elhamkia M, Abbasi F, Alaghi A, Djafari F, Eslahi M, Gohari NSF, Ghorbaninejad P, Hasanzadeh M, Jafari A, Jibril AT, Khorasaniha R, Mansouri E, Monfared V, Rezaee S, Salehian A, Shahavandi M, Sheikhi L, Milajerdi A (2021). Administration of Dietary Antioxidants for Patients With Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials. Complementary Therapies in Medicine, 63(), -.

Chicago

Shahinfar H, Payandeh N, Elhamkia M, Abbasi F, Alaghi A, Djafari F, Eslahi M, et al.. "Administration of Dietary Antioxidants for Patients With Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials." Complementary Therapies in Medicine 63, no. (2021): -.

Harvard

Shahinfar H et al. (2021) 'Administration of Dietary Antioxidants for Patients With Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials', Complementary Therapies in Medicine, 63(), pp. -.

Vancouver

Shahinfar H, Payandeh N, Elhamkia M, Abbasi F, Alaghi A, Djafari F, et al.. Administration of Dietary Antioxidants for Patients With Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials. Complementary Therapies in Medicine. 2021;63():-.

BibTex

@article{ author = {Shahinfar H and Payandeh N and Elhamkia M and Abbasi F and Alaghi A and Djafari F and Eslahi M and Gohari NSF and Ghorbaninejad P and Hasanzadeh M and Jafari A and Jibril AT and Khorasaniha R and Mansouri E and Monfared V and Rezaee S and Salehian A and Shahavandi M and Sheikhi L and Milajerdi A}, title = {Administration of Dietary Antioxidants for Patients With Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials}, journal = {Complementary Therapies in Medicine}, volume = {63}, number = {}, pages = {-}, year = {2021} }

RIS

TY - JOUR
AU - Shahinfar H
AU - Payandeh N
AU - Elhamkia M
AU - Abbasi F
AU - Alaghi A
AU - Djafari F
AU - Eslahi M
AU - Gohari NSF
AU - Ghorbaninejad P
AU - Hasanzadeh M
AU - Jafari A
AU - Jibril AT
AU - Khorasaniha R
AU - Mansouri E
AU - Monfared V
AU - Rezaee S
AU - Salehian A
AU - Shahavandi M
AU - Sheikhi L
AU - Milajerdi A
TI - Administration of Dietary Antioxidants for Patients With Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials
JO - Complementary Therapies in Medicine
VL - 63
IS -
SP -
EP -
PY - 2021
ER -

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