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Legume Intake and Risk of Nonalcoholic Fatty Liver Disease Publisher Pubmed



Bahrami A1 ; Teymoori F1 ; Eslamparast T2 ; Sohrab G2 ; Hejazi E2 ; Poustchi H3 ; Hekmatdoost A2
Authors
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Authors Affiliations
  1. 1. Student Research Committee, Department and Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  2. 2. Department of Clinical Nutrition and Dietetics, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology, Research Institute, Shahid Beheshti University of Medical Sciences, No 7, West Arghavan St., Farahzadi Blvd., 1981619573, P.O.Box: 19395-4741, Tehran, Iran
  3. 3. Liver and Pancreatobiliary Research Group, Digestive Disease Research Institute, Tehran, Iran

Source: Indian Journal of Gastroenterology Published:2019


Abstract

Background: It is known that diet plays a pivotal role in the pathogenesis and management of nonalcoholic fatty liver disease (NAFLD); however, the knowledge on the role of different food groups such as legumes is not enough. Methods: We designed this study to assess the relationship between legume intake and risk of NAFLD in framework of a case-control study among Tehrani adults. One hundred and ninety-six newly diagnosed patients with NAFLD and 803 controls were studied, and their dietary intake was assessed using a valid and reliable food frequency questionnaire. Conditional logistic regression was used to determine the odds ratio (OR) of NAFLD per increase of one serving/week dietary legumes, lentil, and beans adjusting for potential confounders. Results: In energy-adjusted model, greater intake of legumes, lentils, and beans was associated with a lower risk of NAFLD. These risk associations remained significant after adjusting for all known risk factors of NAFLD. OR of NAFLD in adjusted models for higher dietary intake of legumes, lentils, and beans were 0.73 (0.64–0.84), 0.61 (0.46–0.78), and 0.35 (0.17–0.74), respectively. Conclusion: Our findings suggest that higher intake of total legumes (beans, lentils, and peas) was associated with lower risk of NAFLD. [Figure not available: see fulltext.]. © 2019, Indian Society of Gastroenterology.
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