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Bacterial-Derived Biopolymers: Advanced Natural Nanomaterials for Drug Delivery and Tissue Engineering Publisher



Mokhtarzadeh A1, 2 ; Alibakhshi A3 ; Hejazi M4 ; Omidi Y1 ; Ezzati Nazhad Dolatabadi J1
Authors
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Authors Affiliations
  1. 1. Research Center for Pharmaceutical Nanotechnology, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
  2. 2. Department of Biotechnology, Higher Education Institute of Rab-Rashid, Tabriz, Iran
  3. 3. Department of Biotechnology, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  4. 4. School of Medicine, Gonabad University of Medical Sciences, Gonabad, Iran

Source: TrAC - Trends in Analytical Chemistry Published:2016


Abstract

There are several biocompatible and biodegradable biopolymers, which found tremendous medical and pharmaceutical applications and currently receiving unprecedented attention. Various microorganisms can synthesize a variety of these biopolymers such as polysaccharides, polyamides and polyesters, which could be used for development of new generation of drug carriers and tissue repairing materials. The size, charge, chemical structure and other physicochemical properties of bacterial biodegradable polymers represent a good compatibility in development of tissue scaffolds and also as delivery vehicles of therapeutic agents. Here, we highlight recent advances in engineering biopolymers derived from bacteria, especially for drug delivery and tissue engineering. © 2016 Elsevier B.V.
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