Lncrnas in the Regulation of Endometrial Receptivity for Embryo Implantation

Lncrnas in the Regulation of Endometrial Receptivity for Embryo Implantation Publisher Pubmed

Hasanabadi HE¹ ; Govahi A² ; Chaichian S² ; Mehdizadeh M³ ; Haghighi L² ; Ajdary M²

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1. Department of Pediatric Nursing and NICU, School of Nursing & Midwifery, Tehran University of Medical Sci-ences, Tehran, Iran
2. Endometriosis Research Center, Iran University of Medical Sciences, Tehran, Iran
3. Reproductive Sciences and Technology Research Center, Department of Anatomy, Iran University of Medical Sciences, Tehran, Iran

Source: Jornal Brasileiro de Reproducao Assistida Published:2024

Abstract

The development of endometrial receptivity is crucial for successful embryo implantation and the initiation of pregnancy. Understanding the molecular regulatory processes that transform the endometrium into a receptive phase is essential for enhancing implantation rates in fertility treatments, such as in vitro fertilization (IVF). Long non-coding RNAs (lncRNAs) play a pivotal role as gene regulators and have been examined in the endometrium. This review offers current insights into the role of lncRNAs in regulating endometrial receptivity. Considering the significant variation in endometrial remodeling among species, we summarize the key events in the human endometrial cycle and discuss the identified lncRNAs in both humans and other species, which may play a crucial role in establishing receptivity. Notably, there are 742 lncRNAs in humans and 4438 lncRNAs that have the potential to modulate endometrial receptivity. Additionally, lncRNAs regulating matrix metalloproteinases (MMPs) and Let-7 have been observed in both species. Future investigations should explore the potential of lncRNAs as therapeutic targets and/or biomarkers for diagnosing and improving endometrial receptivity in human fertility therapy. © 2024, SBRA - Associacao Brasileira de Reproducao Assistida (Brazilian Society of Assisted Reproduction). All rights reserved.

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Style	Citing Format
MLA	Hasanabadi HE, et al.. "Lncrnas in the Regulation of Endometrial Receptivity for Embryo Implantation." Jornal Brasileiro de Reproducao Assistida, vol. 28, no. 3, 2024, pp. 503-510.
APA	Hasanabadi HE, Govahi A, Chaichian S, Mehdizadeh M, Haghighi L, Ajdary M (2024). Lncrnas in the Regulation of Endometrial Receptivity for Embryo Implantation. Jornal Brasileiro de Reproducao Assistida, 28(3), 503-510.
Chicago	Hasanabadi HE, Govahi A, Chaichian S, Mehdizadeh M, Haghighi L, Ajdary M. "Lncrnas in the Regulation of Endometrial Receptivity for Embryo Implantation." Jornal Brasileiro de Reproducao Assistida 28, no. 3 (2024): 503-510.
Harvard	Hasanabadi HE et al. (2024) 'Lncrnas in the Regulation of Endometrial Receptivity for Embryo Implantation', Jornal Brasileiro de Reproducao Assistida, 28(3), pp. 503-510.
Vancouver	Hasanabadi HE, Govahi A, Chaichian S, Mehdizadeh M, Haghighi L, Ajdary M. Lncrnas in the Regulation of Endometrial Receptivity for Embryo Implantation. Jornal Brasileiro de Reproducao Assistida. 2024;28(3):503-510.
BibTex	@article{ author = {Hasanabadi HE and Govahi A and Chaichian S and Mehdizadeh M and Haghighi L and Ajdary M}, title = {Lncrnas in the Regulation of Endometrial Receptivity for Embryo Implantation}, journal = {Jornal Brasileiro de Reproducao Assistida}, volume = {28}, number = {3}, pages = {503-510}, year = {2024} }
RIS	TY - JOUR AU - Hasanabadi HE AU - Govahi A AU - Chaichian S AU - Mehdizadeh M AU - Haghighi L AU - Ajdary M TI - Lncrnas in the Regulation of Endometrial Receptivity for Embryo Implantation JO - Jornal Brasileiro de Reproducao Assistida VL - 28 IS - 3 SP - 503 EP - 510 PY - 2024 ER -

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