Micrornas 29, 150, 155, 223 Level and Their Relation to Viral and Immunological Markers in Hiv-1 Infected Naive Patients

Micrornas 29, 150, 155, 223 Level and Their Relation to Viral and Immunological Markers in Hiv-1 Infected Naive Patients Publisher

Moghoofei M¹ ; Bokharaeisalim F^{1, 2} ; Esghaei M¹ ; Keyvani H¹ ; Honardoost M³ ; Mostafaei S^{4, 5} ; Ghasemi A⁶ ; Tavakoli A¹ ; Javanmard D¹ ; Babaei F⁷ ; Garshasbi S² ; Monavari SH¹

Show Affiliations

1. Department of Virology, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran
2. HIV Laboratory of National Center, Vice Chancellor for Health, Iran University of Medical Sciences, Tehran, Iran
3. Endocrine Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences, Tehran, Iran
4. Department of Community Medicine, Faculty of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran
5. Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran
6. Department of Materials Science and Engineering, Sharif University of Technology, Tehran, Iran
7. Department of Microbiology, Faculty of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran

Source: Future Virology Published:2018

Abstract

Aim: The aim of this study was to assess the relationship between microRNAs and viral and immunological markers in HIV-1 infection. Materials & methods: The expression level of miRNAs was evaluated in 60 HIV-1 patients and 20 healthy controls using real-time PCR assays. Results: The results showed that among all miRNAs, miR-29 and miR-150 were significantly downregulated in HIV-1 patients compared with healthy controls, while miR-155 and miR-223 were significantly upregulated compared with healthy controls (p < 0.001 for all comparisons). Conclusion: The mentioned miRNAs seem to influence the clinical progression of HIV-1 infection in naive patients. Moreover, determining the profiles of miRNAs involved in the pathogenesis of HIV infection and manipulating these miRNAs could lead to opening a new gate to HIV-1 infection control. © 2018 Future Medicine Ltd.

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Style	Citing Format
MLA	Moghoofei M, et al.. "Micrornas 29, 150, 155, 223 Level and Their Relation to Viral and Immunological Markers in Hiv-1 Infected Naive Patients." Future Virology, vol. 13, no. 9, 2018, pp. 637-645.
APA	Moghoofei M, Bokharaeisalim F, Esghaei M, Keyvani H, Honardoost M, Mostafaei S, Ghasemi A, Tavakoli A, Javanmard D, Babaei F, Garshasbi S, Monavari SH (2018). Micrornas 29, 150, 155, 223 Level and Their Relation to Viral and Immunological Markers in Hiv-1 Infected Naive Patients. Future Virology, 13(9), 637-645.
Chicago	Moghoofei M, Bokharaeisalim F, Esghaei M, Keyvani H, Honardoost M, Mostafaei S, Ghasemi A, et al.. "Micrornas 29, 150, 155, 223 Level and Their Relation to Viral and Immunological Markers in Hiv-1 Infected Naive Patients." Future Virology 13, no. 9 (2018): 637-645.
Harvard	Moghoofei M et al. (2018) 'Micrornas 29, 150, 155, 223 Level and Their Relation to Viral and Immunological Markers in Hiv-1 Infected Naive Patients', Future Virology, 13(9), pp. 637-645.
Vancouver	Moghoofei M, Bokharaeisalim F, Esghaei M, Keyvani H, Honardoost M, Mostafaei S, et al.. Micrornas 29, 150, 155, 223 Level and Their Relation to Viral and Immunological Markers in Hiv-1 Infected Naive Patients. Future Virology. 2018;13(9):637-645.
BibTex	@article{ author = {Moghoofei M and Bokharaeisalim F and Esghaei M and Keyvani H and Honardoost M and Mostafaei S and Ghasemi A and Tavakoli A and Javanmard D and Babaei F and Garshasbi S and Monavari SH}, title = {Micrornas 29, 150, 155, 223 Level and Their Relation to Viral and Immunological Markers in Hiv-1 Infected Naive Patients}, journal = {Future Virology}, volume = {13}, number = {9}, pages = {637-645}, year = {2018} }
RIS	TY - JOUR AU - Moghoofei M AU - Bokharaeisalim F AU - Esghaei M AU - Keyvani H AU - Honardoost M AU - Mostafaei S AU - Ghasemi A AU - Tavakoli A AU - Javanmard D AU - Babaei F AU - Garshasbi S AU - Monavari SH TI - Micrornas 29, 150, 155, 223 Level and Their Relation to Viral and Immunological Markers in Hiv-1 Infected Naive Patients JO - Future Virology VL - 13 IS - 9 SP - 637 EP - 645 PY - 2018 ER -

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