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Synergistic Combination of Bioactive Glasses and Polymers for Enhanced Bone Tissue Regeneration Publisher



Kargozar S1 ; Mozafari M2 ; Hill RG3 ; Brouki Milan P4 ; Taghi Joghataei M5, 6 ; Hamzehlou S7 ; Baino F8
Authors
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Authors Affiliations
  1. 1. Department of Modern Sciences and Technologies, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
  2. 2. Bioengineering Research Group, Nanotechnology and Advanced Materials Department, Materials and Energy Research Center (MERC), P.O. Box 14155-4777, Tehran, Iran
  3. 3. Unit of Dental Physical Sciences, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, Mile End Road, London, E1 4NS, United Kingdom
  4. 4. Department of Tissue Engineering and Regenerative Medicine, Faculty of Advanced Technologies in Medicine, Iran University of Medical Sciences, Tehran, Iran
  5. 5. Cellular and Molecular Research Center (CMRC), Iran University of Medical Sciences, Tehran, Iran
  6. 6. Department of Anatomy, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran
  7. 7. Department of Medical Genetics, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  8. 8. Institute of Materials Physics and Engineering, Department of Applied Science and Technology (DISAT), Politecnico di Torino, Torino, Italy

Source: Materials Today: Proceedings Published:2018


Abstract

There are thousands of surgical procedures for the replacement or repair of bone tissues that has been damaged through disease or trauma. In recent years, considerable interest was toward biologically active scaffolds based on similar characteristics to that of tissue/organ. The present review aims to explain the potential of bioactive glass (BG)/polymer composite scaffolds to accelerate bone healing process. BGs have been recently achieved much attention in bone tissue engineering due to their superior features such as osteoconductivity, osteoinductivity, and ability to improve angiogenesis activity deep into the damages tissues. The combination of micro- or nano-sized BG inclusions with different synthetic and natural polymers is proposed as an effective approach to produce composite scaffolds which can be used in a variety of dental and orthopaedic applications. © 2018 Elsevier Ltd.
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