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Biomedical Applications of Nanoceria: New Roles for an Old Player Publisher Pubmed



Kargozar S1 ; Baino F2 ; Hoseini SJ3 ; Hamzehlou S4, 5 ; Darroudi M6 ; Verdi J7 ; Hasanzadeh L3 ; Kim HW8, 9, 10 ; Mozafari M11, 12, 13
Authors
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Authors Affiliations
  1. 1. Department of Modern Sciences and Technologies, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
  2. 2. Institute of Materials Physics and Engineering, Department of Applied Science and Technology (DISAT), Politecnico di Torino, Torino, Italy
  3. 3. Department of Medical Biotechnology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
  4. 4. Department of Medical Genetics, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  5. 5. Medical Genetics Network (MeGeNe), Universal Scientific Education and Research Network (USERN), Tehran, Iran
  6. 6. Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
  7. 7. Tissue Engineering and Applied Cell Sciences Department, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran
  8. 8. Institute of Tissue Regeneration Engineering (ITREN), Dankook University, Cheonan, South Korea
  9. 9. Department of Nanobiomedical Science and BK21 PLUS NBM Global, Research Center for Regenerative Medicine, Dankook University, Cheonan, South Korea
  10. 10. Department of Biomaterials Science, School of Dentistry, Dankook University, Cheonan, South Korea
  11. 11. Bioengineering Research Group, Nanotechnology and Advanced Materials Department, Materials and Energy Research Center (MERC), Tehran, Iran
  12. 12. Cellular and Molecular Research Center, Iran University of Medical Sciences (IUMS), Tehran, Iran
  13. 13. Department of Tissue Engineering and Regenerative Medicine, Faculty of Advanced Technologies in Medicine, Iran University of Medical Sciences (IUMS), Tehran, Iran

Source: Nanomedicine Published:2018


Abstract

The use of different biomaterials with the ability to accelerate the repair and regeneration processes is of great importance in tissue engineering strategies. On this point, cerium oxide nanoparticles (CNPs or nanoceria) have recently attracted much attention due to their excellent biological properties including anti-oxidant, anti-inflammation and antibacterial activities as well as high angiogenic potential. The results of incorporation of these nano-sized particles into various constructs and scaffolds designed for tissue engineering applications have proven the success of this strategy in terms of improving healing process of different tissues. In this review, we first summarize the physicochemical and biological properties of nanoceria in brief and then present its usability in tissue engineering strategies based on the currently available published reports. © 2018 2018 Future Medicine Ltd.
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