Adherence to the Dietary Approaches to Stop Hypertension-Style Diet Is Inversely Associated With Chronic Kidney Disease: A Systematic Review and Meta-Analysis of Prospective Cohort Studies Publisher Pubmed



Taghavi M¹ ; Sadeghi A² ; Maleki V³ ; Nasiri M^{4, 5} ; Khodadost M^{6, 7} ; Pirouzi A⁸ ; Rashidbeigi E^{9, 10} ; Sadeghi O^{8, 9, 10} ; Swann O¹¹
Source: Nutrition Research Published:2019

Abstract

No conclusive information is available about the association between the Dietary Approaches to Stop Hypertension (DASH)-style diet and chronic kidney disease (CKD). Hence, we aimed to summarize the findings of prospective cohort studies on the relationship between adherence to the DASH-style diet and risk of CKD. A systematic search was done using relevant keywords in the online databases for relevant publications up through July 2018. In total, we included 6 studies in the current systematic review and meta-analysis, with a total sample size of 568 156 individuals and 9249 cases of CKD. Combining 6 effect sizes from 6 studies revealed a significant inverse association between adherence to the DASH diet and risk of CKD (Combined effect size: 0.72, 95% CI: 0.61-0.85, P <.001). In addition, adherence to a DASH-style diet was inversely associated with a risk of rapid decline in estimated glomerular filtration rate (eGFR) (Combined effect size: 0.74, 95% CI: 0.54-0.99, P =.04) and microalbuminuria (Combined effect size: 0.61, 95% CI: 0.43-0.88, P =.009), but not with low eGFR. Adherence to the DASH-style diet, as a healthy dietary pattern, might be beneficial for the prevention of CKD. © 2019 Elsevier Inc.