Mgl_3741 Gene Contributes to Pathogenicity of Malassezia Globosa in Pityriasis Versicolor

Mgl_3741 Gene Contributes to Pathogenicity of Malassezia Globosa in Pityriasis Versicolor Publisher Pubmed

Aghaei Gharehbolagh S¹ ; Kordbacheh P¹ ; Hashemi SJ^{1, 2} ; Daie Ghazvini R¹ ; Asgari Y³ ; Agha Kuchak Afshari S¹ ; Seyedmousavi S^{4, 5, 6, 7} ; Rezaie S¹

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1. Department of Medical Mycology & Parasitology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
2. Food Microbiology Research Center, Tehran University of Medical Sciences, Tehran, Iran
3. Department of Medical Biotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran
4. Invasive Fungi Research Center, Mazandaran University of Medical Sciences, Sari, Iran
5. Center of Expertise in Microbiology, Infection Biology and Antimicrobial Pharmacology, Tehran, Iran
6. Department of Medical Microbiology, Center of Expertise in Mycology Radboudumc/CWZ, Nijmegen, Netherlands
7. Molecular Microbiology Section, Laboratory of Clinical Infectious Diseases (LCID), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, United States

Source: Mycoses Published:2018

Abstract

Dihydroxyacid dehydratase (DHAD) is a key enzyme in biosynthetic pathway of isoleucine and valine. This pathway is absent in human but exists in various organisms such as fungi. Using RNA-seq analysis in this study, we identified MGL_3741gene which encodes DHAD protein in Malassezia globosa (M. globosa). Furthermore, we found that mentioned gene is homologous to the Ustilago maydis, Saccharomyces cerevisiae, Aspergillus flavus, and Aspergillus fumigatus ILV3P. For understanding the probable role of this gene in pathogenicity of M. globosa, we applied Real-time PCR to investigate the differentially expressed of the MGL_3741 gene in healthy and pathogenic states. Our results indicate a significant difference between two mentioned stats. These results revealed that ILV3-like gene in M. globosa can be related to the pathogenicity of this yeast. © 2018 Blackwell Verlag GmbH

2. Unveiling the Structure of Gpi-Anchored Protein of Malassezia Globosa and Its Pathogenic Role in Pityriasis Versicolor, Journal of Molecular Modeling (2021)

3. Detection and Identification of Malassezia Species in Domestic Animals and Aquatic Birds by Pcr-Rflp, Iranian Journal of Veterinary Research (2015)

4. Effect of Various Ultraviolet Radiation on Antifungal Susceptibility Pattern and Related Genes Expression in Malassezia Sympodialis, Gene Reports (2019)

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Sassan Rezaie (3)

Seyed Jamal Hashemi Hezaveh (1)

Style	Citing Format
MLA	Aghaei Gharehbolagh S, et al.. "Mgl_3741 Gene Contributes to Pathogenicity of Malassezia Globosa in Pityriasis Versicolor." Mycoses, vol. 61, no. 12, 2018, pp. 938-944.
APA	Aghaei Gharehbolagh S, Kordbacheh P, Hashemi SJ, Daie Ghazvini R, Asgari Y, Agha Kuchak Afshari S, Seyedmousavi S, Rezaie S (2018). Mgl_3741 Gene Contributes to Pathogenicity of Malassezia Globosa in Pityriasis Versicolor. Mycoses, 61(12), 938-944.
Chicago	Aghaei Gharehbolagh S, Kordbacheh P, Hashemi SJ, Daie Ghazvini R, Asgari Y, Agha Kuchak Afshari S, Seyedmousavi S, Rezaie S. "Mgl_3741 Gene Contributes to Pathogenicity of Malassezia Globosa in Pityriasis Versicolor." Mycoses 61, no. 12 (2018): 938-944.
Harvard	Aghaei Gharehbolagh S et al. (2018) 'Mgl_3741 Gene Contributes to Pathogenicity of Malassezia Globosa in Pityriasis Versicolor', Mycoses, 61(12), pp. 938-944.
Vancouver	Aghaei Gharehbolagh S, Kordbacheh P, Hashemi SJ, Daie Ghazvini R, Asgari Y, Agha Kuchak Afshari S, et al.. Mgl_3741 Gene Contributes to Pathogenicity of Malassezia Globosa in Pityriasis Versicolor. Mycoses. 2018;61(12):938-944.
BibTex	@article{ author = {Aghaei Gharehbolagh S and Kordbacheh P and Hashemi SJ and Daie Ghazvini R and Asgari Y and Agha Kuchak Afshari S and Seyedmousavi S and Rezaie S}, title = {Mgl_3741 Gene Contributes to Pathogenicity of Malassezia Globosa in Pityriasis Versicolor}, journal = {Mycoses}, volume = {61}, number = {12}, pages = {938-944}, year = {2018} }
RIS	TY - JOUR AU - Aghaei Gharehbolagh S AU - Kordbacheh P AU - Hashemi SJ AU - Daie Ghazvini R AU - Asgari Y AU - Agha Kuchak Afshari S AU - Seyedmousavi S AU - Rezaie S TI - Mgl_3741 Gene Contributes to Pathogenicity of Malassezia Globosa in Pityriasis Versicolor JO - Mycoses VL - 61 IS - 12 SP - 938 EP - 944 PY - 2018 ER -

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