Development of a Core Measurement Set for Research in Degenerative Cervical Myelopathy: A Study Protocol (Ao Spine Recode-Dcm Cms)

Development of a Core Measurement Set for Research in Degenerative Cervical Myelopathy: A Study Protocol (Ao Spine Recode-Dcm Cms) Publisher Pubmed

Davies BM¹ ; Yanez Touzet A² ; Mowforth OD³ ; Lee KS⁴ ; Khan D⁵ ; Furlan JC⁶ ; Fehlings MG⁷ ; Harrop JS⁸ ; Zipser CM⁹ ; Rodriguespinto R^{10, 11} ; Milligan J¹² ; Sarewitz E¹³ ; Curt A¹⁴ ; Rahimimovaghar V¹⁵ Show All Authors

Davies BM¹
Yanez Touzet A²
Mowforth OD³
Lee KS⁴
Khan D⁵
Furlan JC⁶
Fehlings MG⁷
Harrop JS⁸
Zipser CM⁹
Rodriguespinto R^{10, 11}
Milligan J¹²
Sarewitz E¹³
Curt A¹⁴
Rahimimovaghar V¹⁵
Aarabi B¹⁶
Boerger TF¹⁷
Tetreault L^{18, 19}
Chen R²⁰
Guest JD²¹
Kalsiryan S²²
Sadler I¹³
Widdop S¹³
Mcnair AGK^{23, 24}
Kwon BK²⁵
Kotter MRN^{26, 27}

Show Affiliations

1. Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom
2. School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, United Kingdom
3. Department of Academic Neurosurgery, University of Cambridge, Cambridge, United Kingdom
4. Bristol Medical School, Faculty of Health Sciences, University of Bristol, Bristol, United Kingdom
5. Academic Neurosurgery Unit, University College London, London, United Kingdom
6. Department of Medicine, Division of Physical Medicine and Rehabilitation, University of Toronto, Toronto, ON, Canada
7. Division of Neurosurgery and Spinal Program, Toronto Western Hospital, Toronto, ON, Canada
8. Thomas Jefferson University, Jefferson Health System, St Louis, MO, United States
9. Neurology, University Hospital Balgrist, Zurich, Switzerland
10. Spinal Unit (UVM), Department of Orthopaedics, Centro Hospitalar Universitario Do Porto Epe, Porto, Portugal
11. Instituto de Ciencias Biomedicas Abel Salazar, Porto, Portugal
12. Family Medicine, McMaster University, Hamilton, ON, Canada
13. Myelopathy.org, Cambridge, United Kingdom
14. University Hospital Balgrist, Zurich, Switzerland
15. Academic Department of Neurological Surgery, Sina Trauma and Surgery Research Center, Tehran, Iran
16. Division of Neurosurgery, University of Maryland Baltimore, Baltimore, MD, United States
17. Neurosurgery, Medical College of Wisconsin, Wauwatosa, WI, United States
18. Department of Surgery, University of Toronto, Toronto, ON, Canada
19. Department of Medicine, University College Cork, Cork, Ireland
20. Neurology, Toronto Western Hospital, Toronto, ON, Canada
21. Department of Neurological Surgery, University of Miami Miller School of Medicine, Miami, FL, United States
22. Toronto Rehabilitation Institute, Toronto, ON, Canada
23. Centre for Surgical Research, Bristol Medical School: Population Health Sciences, University of Bristol, Avon, Bristol, United Kingdom
24. Gi Surgery, North Bristol Nhs Trust, Bristol, United Kingdom
25. Department of Orthopaedics, University of British Columbia, Blusson Spinal Cord Center, Vancouver, BC, Canada
26. Department of Clinical Neurosurgery, University of Cambridge, Cambridge, United Kingdom
27. Department of Clinical Neurosciences, Ann McLaren Laboratory of Regenerative Medicine, Cambridge, United Kingdom

Source: BMJ Open Published:2022

Abstract

Introduction Progress in degenerative cervical myelopathy (DCM) is hindered by inconsistent measurement and reporting. This impedes data aggregation and outcome comparison across studies. This limitation can be reversed by developing a core measurement set (CMS) for DCM research. Previously, the AO Spine Research Objectives and Common Data Elements for DCM (AO Spine RECODE-DCM) defined € what' should be measured in DCM: the next step of this initiative is to determine € how' to measure these features. This protocol outlines the steps necessary for the development of a CMS for DCM research and audit. Methods and analysis The CMS will be developed in accordance with the guidance developed by the Core Outcome Measures in Effectiveness Trials and the Consensus-based Standards for the selection of health Measurement Instruments. The process involves five phases. In phase 1, the steering committee agreed on the constructs to be measured by sourcing consensus definitions from patients, professionals and the literature. In phases 2 and 3, systematic reviews were conducted to identify tools for each construct and aggregate their evidence. Constructs with and without tools were identified, and scoping reviews were conducted for constructs without tools. Evidence on measurement properties, as well as on timing of assessments, are currently being aggregated. These will be presented in phase 4: a consensus meeting where a multi-disciplinary panel of experts will select the instruments that will form the CMS. Following selection, guidance on the implementation of the CMS will be developed and disseminated (phase 5). A preliminary CMS review scheduled at 4 years from release. Ethics and dissemination Ethical approval was obtained from the University of Cambridge (HBREC2019.14). Dissemination strategies will include peer-reviewed scientific publications; conference presentations; podcasts; the identification of AO Spine RECODE-DCM ambassadors; and engagement with relevant journals, funders and the DCM community. © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

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Style	Citing Format
MLA	Davies BM, et al.. "Development of a Core Measurement Set for Research in Degenerative Cervical Myelopathy: A Study Protocol (Ao Spine Recode-Dcm Cms)." BMJ Open, vol. 12, no. 6, 2022, pp. -.
APA	Davies BM, Yanez Touzet A, Mowforth OD, Lee KS, Khan D, Furlan JC, Fehlings MG, Harrop JS, Zipser CM, Rodriguespinto R, Milligan J, Sarewitz E, Curt A, Rahimimovaghar V, Aarabi B, Boerger TF, Tetreault L, Chen R, Guest JD, ... Kotter MRN (2022). Development of a Core Measurement Set for Research in Degenerative Cervical Myelopathy: A Study Protocol (Ao Spine Recode-Dcm Cms). BMJ Open, 12(6), -.
Chicago	Davies BM, Yanez Touzet A, Mowforth OD, Lee KS, Khan D, Furlan JC, Fehlings MG, et al.. "Development of a Core Measurement Set for Research in Degenerative Cervical Myelopathy: A Study Protocol (Ao Spine Recode-Dcm Cms)." BMJ Open 12, no. 6 (2022): -.
Harvard	Davies BM et al. (2022) 'Development of a Core Measurement Set for Research in Degenerative Cervical Myelopathy: A Study Protocol (Ao Spine Recode-Dcm Cms)', BMJ Open, 12(6), pp. -.
Vancouver	Davies BM, Yanez Touzet A, Mowforth OD, Lee KS, Khan D, Furlan JC, et al.. Development of a Core Measurement Set for Research in Degenerative Cervical Myelopathy: A Study Protocol (Ao Spine Recode-Dcm Cms). BMJ Open. 2022;12(6):-.
BibTex	@article{ author = {Davies BM and Yanez Touzet A and Mowforth OD and Lee KS and Khan D and Furlan JC and Fehlings MG and Harrop JS and Zipser CM and Rodriguespinto R and Milligan J and Sarewitz E and Curt A and Rahimimovaghar V and Aarabi B and Boerger TF and Tetreault L and Chen R and Guest JD and Kalsiryan S and Sadler I and Widdop S and Mcnair AGK and Kwon BK and Kotter MRN}, title = {Development of a Core Measurement Set for Research in Degenerative Cervical Myelopathy: A Study Protocol (Ao Spine Recode-Dcm Cms)}, journal = {BMJ Open}, volume = {12}, number = {6}, pages = {-}, year = {2022} }
RIS	TY - JOUR AU - Davies BM AU - Yanez Touzet A AU - Mowforth OD AU - Lee KS AU - Khan D AU - Furlan JC AU - Fehlings MG AU - Harrop JS AU - Zipser CM AU - Rodriguespinto R AU - Milligan J AU - Sarewitz E AU - Curt A AU - Rahimimovaghar V AU - Aarabi B AU - Boerger TF AU - Tetreault L AU - Chen R AU - Guest JD AU - Kalsiryan S AU - Sadler I AU - Widdop S AU - Mcnair AGK AU - Kwon BK AU - Kotter MRN TI - Development of a Core Measurement Set for Research in Degenerative Cervical Myelopathy: A Study Protocol (Ao Spine Recode-Dcm Cms) JO - BMJ Open VL - 12 IS - 6 SP - EP - PY - 2022 ER -

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