Β Cell and Autophagy: What Do We Know?

Β Cell and Autophagy: What Do We Know? Publisher

Mohammadimotlagh HR¹ ; Sadeghalvad M² ; Yavari N³ ; Primavera R⁴ ; Soltani S⁵ ; Chetty S⁴ ; Ganguly A⁴ ; Regmi S⁴ ; Floyel T⁶ ; Kaur S⁶ ; Mirza AH^{6, 7} ; Thakor AS⁴ ; Pociot F^{6, 8} ; Yarani R^{4, 6}

Source: Biomolecules Published:2023

Abstract

Pancreatic β cells are central to glycemic regulation through insulin production. Studies show autophagy as an essential process in β cell function and fate. Autophagy is a catabolic cellular process that regulates cell homeostasis by recycling surplus or damaged cell components. Impaired autophagy results in β cell loss of function and apoptosis and, as a result, diabetes initiation and progress. It has been shown that in response to endoplasmic reticulum stress, inflammation, and high metabolic demands, autophagy affects β cell function, insulin synthesis, and secretion. This review highlights recent evidence regarding how autophagy can affect β cells’ fate in the pathogenesis of diabetes. Furthermore, we discuss the role of important intrinsic and extrinsic autophagy modulators, which can lead to β cell failure. © 2023 by the authors.

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Style	Citing Format
MLA	Mohammadimotlagh HR, et al.. "Β Cell and Autophagy: What Do We Know?." Biomolecules, vol. 13, no. 4, 2023, pp. -.
APA	Mohammadimotlagh HR, Sadeghalvad M, Yavari N, Primavera R, Soltani S, Chetty S, Ganguly A, Regmi S, Floyel T, Kaur S, Mirza AH, Thakor AS, Pociot F, Yarani R (2023). Β Cell and Autophagy: What Do We Know?. Biomolecules, 13(4), -.
Chicago	Mohammadimotlagh HR, Sadeghalvad M, Yavari N, Primavera R, Soltani S, Chetty S, Ganguly A, et al.. "Β Cell and Autophagy: What Do We Know?." Biomolecules 13, no. 4 (2023): -.
Harvard	Mohammadimotlagh HR et al. (2023) 'Β Cell and Autophagy: What Do We Know?', Biomolecules, 13(4), pp. -.
Vancouver	Mohammadimotlagh HR, Sadeghalvad M, Yavari N, Primavera R, Soltani S, Chetty S, et al.. Β Cell and Autophagy: What Do We Know?. Biomolecules. 2023;13(4):-.
BibTex	@article{ author = {Mohammadimotlagh HR and Sadeghalvad M and Yavari N and Primavera R and Soltani S and Chetty S and Ganguly A and Regmi S and Floyel T and Kaur S and Mirza AH and Thakor AS and Pociot F and Yarani R}, title = {Β Cell and Autophagy: What Do We Know?}, journal = {Biomolecules}, volume = {13}, number = {4}, pages = {-}, year = {2023} }
RIS	TY - JOUR AU - Mohammadimotlagh HR AU - Sadeghalvad M AU - Yavari N AU - Primavera R AU - Soltani S AU - Chetty S AU - Ganguly A AU - Regmi S AU - Floyel T AU - Kaur S AU - Mirza AH AU - Thakor AS AU - Pociot F AU - Yarani R TI - Β Cell and Autophagy: What Do We Know? JO - Biomolecules VL - 13 IS - 4 SP - EP - PY - 2023 ER -

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