Evaluation of the Accuracy of Various Dose Calculation Algorithms of a Commercial Treatment Planning System in the Presence of Hip Prosthesis and Comparison With Monte Carlo Publisher Pubmed



Mohammadi K¹ ; Hassani M² ; Ghorbani M³ ; Farhood B⁴ ; Knaup C⁵ Show Affiliations
Source: Journal of Cancer Research and Therapeutics Published:2017

Abstract

Purpose: High atomic number elements are commonly used in a hip prosthesis which can cause uncertainty in accurate dose calculations in radiation therapy. The aim of this study is to assess the accuracy of the three various algorithms of ISOgray treatment planning system in the presence of hip prosthesis by Monte Carlo (MC). Materials and Methods: A MC model of Siemens PRIMUS linear accelerator has been built and verified by the measured data of the different algorithms of ISOgray treatment planning systems (TPS) in 6 and 15 MV photon beam energies. Two types of hip prosthesis have been used: stainless steel and titanium. The accuracy of mentioned dose calculation algorithms in the presence of hip prosthesis was evaluated. Results: There were 24.78%, 27.68%, and 27.72% errors in fast Fourier transform (FFT) Convolution, collapsed cone (CC), and superposition in 6 MV photon beam and 26.45%, 30.45%, and 28.63% in 15 MV photon beam for titanium type, respectively. However, there were 32.84%, 35.89%, and 35.57% in 6 MV photon beam and 38.81%, 47.31%, and 39.91% errors in 15 MV photon beam in steel type, respectively. In addition, the ISOgray TPS algorithms are not able to predict the dose enhancement and reduction at the proximal and distal prosthesis interfaces, respectively. Conclusions: Hip prosthesis creates a considerable disturbance in dose distribution which cannot be predicted accurately by the FFT convolution, CC, and superposition algorithms. It is recommended to use of MC-based TPS for the treatment fields including the hip prosthesis.