Natural Compounds That May Assist in the Prevention of Oral Squamous Cell Carcinoma Publisher



Aghahosseini F^{1, 2} ; Moosavi MS³ ; Davari M⁴ Show Affiliations
Source: Australian Journal of Herbal and Naturopathic Medicine Published:2021

Abstract

Aim Oral cavity cancer is one of the most common and deadly malignancies of the head and neck, and is considered the sixth common cancer worldwide. Usual treatments have not been able to increase the survival of patients with oral squamous cell carcinoma (OSCC) over decades, indicating a need for alternative and complementary treatments. This review study aims to gather components that may be effective in the prevention or inhibition of the progress of oral squamous cell carcinoma. Method We searched, gathered and assessed English articles in the databases of Google Scholar, Scopus, Pubmed and Science Direct using keywords of oral squamous cell carcinoma or OSCC and herbal medicine from 1960 to February 2020. Results and Conclusion This overall review could be used firstly at the prevention phase through dietary recommendations and medication prescriptions regarding the effective dose for individuals with premalignant lesions or who are at risk; additionally, the components could help people to have a healthier lifestyle, thereby reducing the early occurrence and high global prevalence of OSCC over the following decades. Moreover, these components could be used as a complementary treatment with high efficiency, low toxicity and long survival. © NHAA 2021.