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First Cases of Sars-Cov-2 in Iran, 2020: Case Series Report



Yavarian J1 ; Shafieijandaghi NZ1 ; Sadeghi K1 ; Malekshahi SS2 ; Salimi V1 ; Nejati A1 ; Ajaminejad F1 ; Ghavvami N1 ; Saadatmand F1 ; Mahfouzi S1 ; Fateminasab G1 ; Parhizgari N1 ; Ahmadi A1 ; Razavi K1 Show All Authors
Authors
  1. Yavarian J1
  2. Shafieijandaghi NZ1
  3. Sadeghi K1
  4. Malekshahi SS2
  5. Salimi V1
  6. Nejati A1
  7. Ajaminejad F1
  8. Ghavvami N1
  9. Saadatmand F1
  10. Mahfouzi S1
  11. Fateminasab G1
  12. Parhizgari N1
  13. Ahmadi A1
  14. Razavi K1
  15. Ghabeshi S1
  16. Saberian M3
  17. Zanjani E1
  18. Namazi F4
  19. Shahbazi T5
  20. Rezaie F6
  21. Erfani H6
  22. Gouya MM6
  23. Dadras MN6
  24. Azad TM1
Show Affiliations
Authors Affiliations
  1. 1. Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Virology, School of Medical Sciences, Tarbiat Modares University, Tehran, Iran
  3. 3. Department of Cellular and Molecular Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. School of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran
  5. 5. Department of Bacteriology, School of Medical Sciences, Tarbiat Modares University, Tehran, Iran
  6. 6. Iranian Center for Communicable Disease Control, Tehran, Iran

Source: Iranian Journal of Public Health Published:2020

Abstract

In Jan 2020, the outbreak of the 2019 novel coronavirus (SARS-CoV-2) in Wuhan, Hubei Province of China spread increasingly to other countries worldwide which WHO declared it as a public health emergency of international concern. Iran was included in the affected countries. Throat swab specimens were collected and tested by using real-time reverse transcription PCR (RT-PCR) kit targeting the E region for screening and RNA dependent RNA polymerase for confirmation. Conventional RT-PCR was conducted for the N region and the PCR products were sequenced by Sanger sequencing. The first seven cases of SARS-CoV-2 infections were identified in Qom, Iran. This report describes the clinical and epidemiological features of the first cases of SARS-CoV-2 confirmed in Iran. Future research should focus on finding the routes of transmission for this virus, including the possibility of transmission from foreign tourists to identify the possible origin of SARS-CoV-2 outbreak in Iran. © 2020, Iranian Journal of Public Health. All rights reserved.
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