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The Spike Protein Mutations and Its Effect on Sars-Cov-2 Pathogenesis Publisher



Zandi M1, 2 ; Soltani S1, 2 ; Sanami S3 ; Rasooli A4, 5
Authors

Source: Journal of Cellular and Molecular Anesthesia Published:2021


Abstract

The severe acute respiratory syndrome coronavirus 2 spike (S) glycoprotein facilitates receptor binding to initiate cell entry that is the critical initial step in the infection cycle. Due to S glycoprotein's pivotal role, in this review, we pointed to show potential functional and structural consequences of S glycoprotein and its variants, which has been related to increased viral load in humans with SARS-CoV-2 infection. © 2021 Journal of Cellular and Molecular Anesthesia. All rights reserved.
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