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Non-Coding Rnas and Aquaporin 4: Their Role in the Pathogenesis of Neurological Disorders Publisher Pubmed



Yaghoobi Z1, 2 ; Seyed Bagher Nazeri SS3 ; Asadi A4 ; Derafsh E5 ; Talebi Taheri A6 ; Tamtaji Z7 ; Dadgostar E8, 9 ; Rahmatidehkordi F1, 2 ; Aschner M10 ; Mirzaei H11 ; Tamtaji OR1, 2 ; Nabavizadeh F1, 2
Authors

Source: Neurochemical Research Published:2024


Abstract

Neurological disorders are a major group of non-communicable diseases affecting quality of life. Non-Coding RNAs (ncRNAs) have an important role in the etiology of neurological disorders. In studies on the genesis of neurological diseases, aquaporin 4 (AQP4) expression and activity have both been linked to ncRNAs. The upregulation or downregulation of several ncRNAs leads to neurological disorder progression by targeting AQP4. The role of ncRNAs and AQP4 in neurological disorders is discussed in this review. © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2023.
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