Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Herbal Medicine in the Treatment of Obsessive Compulsive Disorder: A Review Publisher



Zamani Z1 ; Akhondzadeh S1
Authors
Show Affiliations
Authors Affiliations
  1. 1. Psychiatric Research Center, Roozbeh Hospital, Tehran University of Medical Sciences, Tehran, Iran

Source: Journal of Medicinal Plants Published:2019


Abstract

Obsessive compulsive disorder (OCD) is a severe and debilitating neuropsychiatric condition that is characterized by recurrent and intrusive thought that the affected individual feels compelled to perform in order to reduce the distress. It affects between 1 to 3% of the general population around the world and has some gender-related features. Although selective serotonin reuptake inhibitors, tricyclic antidepressants and cognitive-behavioral therapy are the first line medication and treatment of OCD, an estimated 30% of patients are treatment-resistant and complete functional recovery is rare. Therefore, several researches and trials have been done to develop new pharmacotherapeutic agents or modulate different neurotransmitters for treatment of OCD. In this concept alternative medicine and particular herbal medicine are very interesting in this issue. We focus on some herbal medicine in the treatment of OCD in this review. © 2019 Institute of Medicinal Plants. All rights reserved.
Related Docs
View other Related Docs
1. Amantadine As Adjuvant Therapy in the Treatment of Moderate to Severe Obsessive–Compulsive Disorder: A Double-Blind Randomized Trial With Placebo Control, Psychiatry and Clinical Neurosciences (2019)
2. Comparison of Saffron and Fluvoxamine in the Treatment of Mild to Moderate Obsessive-Compulsive Disorder: A Double Blind, Randomized Clinical Trial, Iranian Journal of Psychiatry (2017)
3. Glutamatergic Medications As Adjunctive Therapy for Moderate to Severe Obsessive-Compulsive Disorder in Adults: A Systematic Review and Meta-Analysis, BMC Pharmacology and Toxicology (2021)
4. Minocycline Combination Therapy With Fluvoxamine in Moderate-To-Severe Obsessive–Compulsive Disorder: A Placebo-Controlled, Double-Blind, Randomized Trial, Psychiatry and Clinical Neurosciences (2016)
5. L-Theanine Combination Therapy With Fluvoxamine in Moderate-To-Severe Obsessive–Compulsive Disorder: A Placebo-Controlled, Double-Blind, Randomized Trial, Psychiatry and Clinical Neurosciences (2023)
6. 5-Hydroxytryptophan As Adjuvant Therapy in Treatment of Moderate to Severe Obsessive-Compulsive Disorder: A Double-Blind Randomized Trial With Placebo Control, International Clinical Psychopharmacology (2020)
7. L-Carnosine As an Adjuvant to Fluvoxamine in Treatment of Obsessive Compulsive Disorder: A Randomized Double-Blind Study, Human Psychopharmacology (2017)
8. Medicinal Plants in the Treatment of Obsessive-Compulsive Disorder: A Review, Current Drug Discovery Technologies (2021)
Experts (# of related papers)
View all Related Experts
Shahin Akhondzadeh Basti (20)
Mohammad Reza Mohammadi (4)
Other Related Docs
9. N-Acetylcysteine Augmentation Therapy for Moderate-To-Severe Obsessive-Compulsive Disorder: Randomized, Double-Blind, Placebo-Controlled Trial, Journal of Clinical Pharmacy and Therapeutics (2016)
10. Fluvoxamine Combination Therapy With Tropisetron for Obsessive-Compulsive Disorder Patients: A Placebo-Controlled, Randomized Clinical Trial, Journal of Psychopharmacology (2019)
11. Riluzole in Augmentation of Fluvoxamine for Moderate to Severe Obsessive–Compulsive Disorder: Randomized, Double-Blind, Placebo-Controlled Study, Psychiatry and Clinical Neurosciences (2016)
12. Minocycline As Adjunctive Treatment to Risperidone in Children With Autistic Disorder: A Randomized, Double-Blind Placebo-Controlled Trial, Journal of Child and Adolescent Psychopharmacology (2016)
13. Herbal Medicines and Phytochemicals for Obsessive–Compulsive Disorder, Phytotherapy Research (2020)
14. Celecoxib As an Adjuvant to Fluvoxamine in Moderate to Severe Obsessive-Compulsive Disorder: A Double-Blind, Placebo-Controlled, Randomized Trial, Pharmacopsychiatry (2015)
15. L-Carnosine As an Adjunctive Therapy to Risperidone in Children With Autistic Disorder: A Randomized, Double-Blind, Placebo-Controlled Trial, Journal of Child and Adolescent Psychopharmacology (2018)
16. L-Carnosine Combination Therapy for Major Depressive Disorder: A Randomized, Double-Blind, Placebo-Controlled Trial, Journal of Affective Disorders (2020)
17. Riluzole for Treatment of Men With Methamphetamine Dependence: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial, Journal of Psychopharmacology (2019)
18. Effect of Memantine Combination Therapy on Symptoms in Patients With Moderate-To-Severe Depressive Disorder: Randomized, Double-Blind, Placebo-Controlled Study, Journal of Clinical Pharmacy and Therapeutics (2017)
19. Correlations Between Single Nucleotide Polymorphisms in Obsessive-Compulsive Disorder With the Clinical Features or Response to Therapy, Journal of Psychiatric Research (2023)
20. Female Infertility and Herbal Medicine, Journal of Medicinal Plants (2017)
21. Palmitoylethanolamide As Adjunctive Therapy for Autism: Efficacy and Safety Results From a Randomized Controlled Trial, Journal of Psychiatric Research (2018)
22. Review of Clinical Studies Targeting Inflammatory Pathways for Individuals With Autism, Frontiers in Psychiatry (2019)
23. Repetitive Transcranial Magnetic Stimulation (Rtms) Improves Symptoms and Reduces Clinical Illness in Patients Suffering From Ocd - Results From a Single-Blind, Randomized Clinical Trial With Sham Cross-Over Condition, Journal of Psychiatric Research (2015)
24. Emerging Drugs for the Treatment of Irritability Associated With Autism Spectrum Disorder, Expert Opinion on Emerging Drugs (2024)
25. N-Acetylcysteine As an Adjunctive Therapy to Risperidone for Treatment of Irritability in Autism: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial of Efficacy and Safety, Clinical Neuropharmacology (2015)