Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Prevalence of Diabetic Retinopathy in Iran: A Systematic Review and Meta-Analysis Publisher



Maroufizadeh S1 ; Almasihashiani A1 ; Hosseini M2 ; Sepidarkish M1 ; Omani Samani R1
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Epidemiology and Reproductive Health, Reproductive Epidemiology Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, 16635-148, Iran
  2. 2. Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, 14155-6446, Iran

Source: International Journal of Ophthalmology Published:2017


Abstract

AIM: To estimate the overall prevalence of diabetic retinopathy (DR) in Iran by a systematic review and Metaanalysis. METHODS: We conducted a search of all published literature on diabetic patients for the prevalence of DR using Web of Sciences, PubMed, Scopus, Google Scholar, and national electronic databases SID, Magiran, and Iranmedex from their inception until September 2016 with standard keywords. Pooled estimates of the DR prevalence and the corresponding 95% confidence intervals (CI) were calculated using random effects models. RESULTS: Thirty-one studies involving 23 729 patients with type I and II diabetes were included. The publication bias assumption for prevalence of DR was rejected by Begg and Egger tests (P=0.825, P=0.057, respectively). The results of Cochran test and I2 statistics showed considerable heterogeneity for prevalence of DR (Q=1278.21, d.f.=30, P<0.001 and I2=97.7%). The prevalence of DR, non-proliferative diabetic retinopathy (NPDR) and proliferative diabetic retinopathy (PDR) in Iranian diabetic patients were 41.9% (95% CI: 35.6-48.2), 32.2% (95% CI: 28.7-35.8), and 13.2% (95% CI: 8.3-18.1), respectively. CONCLUSION: The prevalence of DR in Iran appears a little high. NPDR was more common. This study highlights the necessity for DR screening and management in diabetic patients in Iran. © 2017, International Journal of Ophthalmology (c/o Editorial Office). All rights reserved.
Related Docs
View other Related Docs
1. Complications of Type 2 Diabetes in Iranian Population: An Updated Systematic Review and Meta-Analysis, Diabetes and Metabolic Syndrome: Clinical Research and Reviews (2019)
2. Diabetic Retinopathy Clinical Practice Guidelines: Customized for Iranian Population, Journal of Ophthalmic and Vision Research (2016)
3. Impact of Melatonin Supplementation on Glycemic Parameters in Patients With Type 2 Diabetes: A Systematic Review and Meta-Analysis, Current Pharmaceutical Design (2025)
4. A Stakeholder Perspective on Diabetes Mellitus and Diabetic Retinopathy Care in Iran; a Qualitative Study, Archives of Iranian Medicine (2017)
5. The Relation of Healthy and Western Dietary Patterns to the Risk of Endometrial and Ovarian Cancers: A Systematic Review and Meta-Analysis, International Journal for Vitamin and Nutrition Research (2020)
6. Metabolic Syndrome and Its Components Are Related to a Higher Risk for Albuminuria and Proteinuria: Evidence From a Meta-Analysis on 10,603,067 Subjects From 57 Studies, Diabetes and Metabolic Syndrome: Clinical Research and Reviews (2019)
7. Vitamin D Receptor (Vdr) Gene Polymorphism and Risk of Rheumatoid Arthritis (Ra): Systematic Review and Meta-Analysis, Clinical Rheumatology (2020)
8. Glymphatic Pathway Dysfunction in Severe Obstructive Sleep Apnea: A Meta-Analysis, Sleep Medicine (2025)
Experts (# of related papers)
View all Related Experts
Sakineh Shab-Bidar (34)
Hamed Mohammadi (17)
Other Related Docs
9. Potato Consumption and Risk of All Cause, Cancer and Cardiovascular Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Cohort Studies, Critical Reviews in Food Science and Nutrition (2020)
10. A Posteriori Dietary Patterns and Risk of Pancreatic and Renal Cancers: A Systematic Review and Meta-Analysis, Nutrition and Food Science (2017)
11. Effect of Resveratrol on C-Reactive Protein: An Updated Meta-Analysis of Randomized Controlled Trials, Phytotherapy Research (2021)
12. Evaluation of Blood Levels of C-Reactive Protein Marker in Obstructive Sleep Apnea: A Systematic Review, Meta-Analysis and Meta-Regression, Life (2021)
13. The Association Between Matrix Metallo-Proteinases-9 (Mmp-9) Gene Family Polymorphisms and Risk of Coronary Artery Disease (Cad): A Systematic Review and Meta-Analysis, BMC Cardiovascular Disorders (2020)
14. Is Leukocyte Telomere Length Related With Lung Cancer Risk?: A Meta-Analysis, Iranian Biomedical Journal (2017)
15. Effect of Curcumin on C-Reactive Protein As a Biomarker of Systemic Inflammation: An Updated Meta-Analysis of Randomized Controlled Trials, Phytotherapy Research (2022)
16. Metabolic Syndrome and Its Components Are Associated With Increased Chronic Kidney Disease Risk: Evidence From a Meta-Analysis on 11 109 003 Participants From 66 Studies, International Journal of Clinical Practice (2018)
17. Association Between the Cyp1a1 Mspi Polymorphism and Risk of Head and Neck Cancer: A Meta-Analysis, Scientific Reports (2022)
18. Effect of Serum Lipid Profile on the Risk of Breast Cancer: Systematic Review and Meta-Analysis of 1,628,871 Women, Journal of Clinical Medicine (2022)
19. Does Bracing Control the Progression of Adolescent Idiopathic Scoliosis in Curves Higher Than 40°? a Systematic Review and Meta-Analysis, Asian Spine Journal (2023)
20. Effectiveness of Dry Needling for Improving Pain and Disability in Adults With Tension-Type, Cervicogenic, or Migraine Headaches: Protocol for a Systematic Review, Chiropractic and Manual Therapies (2019)
21. The Effect of Acarbose Treatment on Anthropometric Indices in Adults: A Systematic Review and Meta-Analysis of Randomized Clinical Trials, Clinical Nutrition Open Science (2024)
22. Association Between Il7 Receptor Alpha (Il7ra) Gene Rs6897932 Polymorphism and the Risk of Multiple Sclerosis: A Meta-Regression and Meta-Analysis., Multiple Sclerosis and Related Disorders (2021)
23. The Effect of Personalized Intelligent Digital Systems for Self-Care Training on Type Ii Diabetes: A Systematic Review and Meta-Analysis of Clinical Trials, Acta Diabetologica (2023)
24. Are Alterations Needed in Silybum Marianum (Silymarin) Administration Practices? a Novel Outlook and Meta-Analysis on Randomized Trials Targeting Liver Injury, BMC Complementary Medicine and Therapies (2025)
25. The Long-Term Effect of Exposure to Respirable Particulate Matter on the Incidence of Myocardial Infarction: A Systematic Review and Meta-Analysis Study, Environmental Science and Pollution Research (2022)
26. Coffee Consumption and Cardiovascular Diseases and Mortality in Patients With Type 2 Diabetes: A Systematic Review and Dose–Response Meta-Analysis of Cohort Studies, Nutrition# Metabolism and Cardiovascular Diseases (2021)
27. The Effect of Acarbose on Inflammatory Cytokines and Adipokines in Adults: A Systematic Review and Meta-Analysis of Randomized Clinical Trials, Inflammopharmacology (2024)
28. Body Mass Index and All-Cause Mortality in Chronic Kidney Disease: A Dose–Response Meta-Analysis of Observational Studies, Journal of Renal Nutrition (2017)
29. Image-Guided Cryoablation for Palliation of Painful Bone Metastases: A Systematic Review and Meta-Analysis, Skeletal Radiology (2025)
30. The Effects of Conjugated Linoleic Acid Supplementation on Liver Function Enzymes and Malondialdehyde in Adults: A Grade-Assessed Systematic Review and Dose-Response Meta-Analysis, Pharmacological Research (2022)
31. Evaluation of Plasma/Serum Adiponectin (An Anti-Inflammatory Factor) Levels in Adult Patients With Obstructive Sleep Apnea Syndrome: A Systematic Review and Meta-Analysis, Life (2022)
32. The Effects of Sildenafil on Fetal Doppler Indices: A Systematic Review and Meta-Analysis, Journal of Advances in Medical and Biomedical Research (2020)
33. Evaluation of Serum and Plasma Interleukin-6 Levels in Obstructive Sleep Apnea Syndrome: A Meta-Analysis and Meta-Regression, Frontiers in Immunology (2020)
34. Intestinal Parasites Among Intellectually Disabled Individuals in Iran: A Systematic Review and Meta-Analysis, Gut Pathogens (2021)
35. A Posteriori Dietary Patterns and Risk of Inflammatory Bowel Disease: A Meta-Analysis of Observational Studies, International Journal for Vitamin and Nutrition Research (2020)
36. A Systematic Review, Meta-Analysis, Dose-Response, and Meta-Regression of the Effects of Acarbose Intake on Glycemic Markers in Adults, Journal of Diabetes and Metabolic Disorders (2023)
37. The Impact of Emblica Officinalis (Amla) on Lipid Profile, Glucose, and C-Reactive Protein: A Systematic Review and Meta-Analysis of Randomized Controlled Trials, Diabetes and Metabolic Syndrome: Clinical Research and Reviews (2023)
38. Vitamin D Receptor Gene Polymorphism and Susceptibility to Asthma: Meta-Analysis Based on 17 Case-Control Studies, Annals of Allergy# Asthma and Immunology (2020)
39. Metabolic Phenotypes of Obese, Overweight, and Normal Weight Individuals and Risk of Chronic Kidney Disease: A Systematic Review and Meta-Analysis, Archives of Endocrinology and Metabolism (2019)
40. Fas-670A>G Gene Polymorphism and the Risk of Allograft Rejection After Organ Transplantation: A Systematic Review and Meta-Analysis, Blood Research (2021)
41. Comparison of Cartilage With Temporalis Fascia Tympanoplasty: A Meta-Analysis of Comparative Studies, Laryngoscope (2017)
42. Effect of Statins on the Blood Lipid Profile in Patients With Different Cardiovascular Diseases: A Systematic Review With Meta-Analysis of Randomized Clinical Trials, Current Medicinal Chemistry (2023)
43. Interleukin-10 Gene Promoter Polymorphisms and Susceptibility to Asthma: Systematic Review and Meta-Analysis, Biochemical Genetics (2021)
44. Thalamic Magnetic Susceptibility (Χ) Alterations in Neurodegenerative Diseases: A Systematic Review and Meta-Analysis of Quantitative Susceptibility Mapping Studies, Journal of Magnetic Resonance Imaging (2025)
45. Relevance of Hmlh1-93G>A, 655A>G and 1151T>A Polymorphisms With Colorectal Cancer Susceptibility: A Meta-Analysis Based on 38 Case-Control Studies, Revista da Associacao Medica Brasileira (2018)
46. Effect of Statins on Serum Level of Hs-Crp and Crp in Patients With Cardiovascular Diseases: A Systematic Review and Meta-Analysis of Randomized Controlled Trials, Mediators of Inflammation (2022)
47. Statin Therapy and C-Reactive Protein in Patients With Kidney Disease: A Systematic Review and Meta-Analysis of Randomized Clinical Trials, Current Drug Targets (2025)
48. Dietary Carbohydrate and the Risk of Type 2 Diabetes: An Updated Systematic Review and Dose–Response Meta-Analysis of Prospective Cohort Studies, Scientific Reports (2022)
49. Effect of Statins on the Plasma/Serum Levels of Inflammatory Markers in Patients With Cardiovascular Disease; a Systematic Review and Meta-Analysis of Randomized Clinical Trials, Inflammopharmacology (2022)
50. Effect of Resveratrol on Inflammatory Cytokines: A Meta-Analysis of Randomized Controlled Trials, European Journal of Pharmacology (2021)