Tehran University of Medical Sciences

Science Communicator Platform

Share By
Lipid-Based Nanoparticles for Drug Delivery Systems Publisher



Samimi S1 ; Maghsoudnia N1 ; Eftekhari RB1 ; Dorkoosh F1
Authors

Source: Characterization and Biology of Nanomaterials for Drug Delivery: Nanoscience and Nanotechnology in Drug Delivery Published:2018


Abstract

Solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) have opened new horizons in the pharmaceutical industry since they play a fundamental role in the field of drug delivery. Their success is mainly due to their interesting physicochemical behaviors, such as high bioavailability, capability of administration through different routes, large-scale production, inherent ability to cross the blood brain barrier, and the ability to deliver macromolecules like proteins, oligonucleotides, and DNA. The purpose of this review is to provide a brief description of the advantages, disadvantages, and production techniques, as well as their potential in the drug delivery area so far. © 2019 Elsevier Inc. All rights reserved.
Related Docs
View other Related Docs
1. Role of Physicochemical Factors on the Efficacy and Safety of Lipid-Based Nanosystems As Potential Drug Carriers, Nano (2021)
2. Recent Progress in the Application of Plant-Based Colloidal Drug Delivery Systems in the Pharmaceutical Sciences, Advances in Colloid and Interface Science (2022)
3. Colloidal Chitosan-Integrated Functional Nanoparticles for Combination Cancer Therapy: Synergistic Strategies in Oncology Via Step-Delivery of Genes/Proteins and Small Drugs, Colloids and Interface Science Communications (2026)
Experts (# of related papers)
View all Related Experts
Farid Dorkoosh (2)
Rassoul Dinarvand (2)
Other Related Docs
4. Application of Nano-Based Systems for Drug Delivery and Targeting: A Review, Journal of Nanoparticle Research (2020)
5. Application of Response Surface Method for Preparation, Optimization, and Characterization of Nicotinamide Loaded Solid Lipid Nanoparticles, Advanced Pharmaceutical Bulletin (2018)
6. Oral Delivery of Therapeutic Peptides and Proteins: Technology Landscape of Lipid-Based Nanocarriers, Advanced Drug Delivery Reviews (2022)
7. New Updates Pertaining to Drug Delivery of Local Anesthetics in Particular Bupivacaine Using Lipid Nanoparticles, Nanoscale Research Letters (2016)
8. The Synthesis, Application and Therapeutic Perspectives of Medicinal Plants-Based Solid Lipid Nanoparticles: A Comprehensive Review, Advances in Traditional Medicine (2025)
9. A New Insight Into the Mechanism of Loading of Granisetron, Naltrexone and Risperidone in Poly(Ortho Ester) and Poly (Lactic-Co-Glycolic Acid) As the Controlled Release Drug Delivery Systems Using a Computational Molecular Approach, Journal of Drug Delivery Science and Technology (2024)
10. Oral Delivery of Posaconazole-Loaded Phospholipid-Based Nanoformulation: Preparation and Optimization Using Design of Experiments, Machine Learning, and Topsis, International Journal of Pharmaceutics (2024)
11. Developments in Microfluidics-Enabled Stimuli-Responsive Chitosan Micro/Nanoparticles for Precision Drug and Biomolecule Delivery, Nano-Structures and Nano-Objects (2026)
12. Recent Advances in Engineering Chitosan-Based Nanoplatforms in Biotherapeutic Multi-Delivery for Multi-Targeted Disease Treatments: Promises and Outlooks, Colloids and Interface Science Communications (2025)
13. Chitosan Nanoparticles, As Biological Macromolecule-Based Drug Delivery Systems to Improve the Healing Potential of Artificial Neural Guidance Channels: A Review, International Journal of Biological Macromolecules (2022)
14. Linkers: The Key Elements for the Creation of Efficient Nanotherapeutics, Journal of Controlled Release (2018)