Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Selective Contribution of Bioactive Glasses to Molecular and Cellular Pathways Publisher Pubmed



Rahmati M1 ; Mozafari M2, 3, 4
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Biomaterials, Institute of Clinical Dentistry, University of Oslo, Oslo, 0317, Norway
  2. 2. Bioengineering Research Group, Nanotechnology and Advanced Materials Department, Materials and Energy Research Center (MERC), Tehran, 14155-4777, Iran
  3. 3. Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, 144961-4535, Iran
  4. 4. Department of Tissue Engineering and Regenerative Medicine, Faculty of Advanced Technologies in Medicine, Iran University of Medical Sciences, Tehran, 144961-4535, Iran

Source: ACS Biomaterials Science and Engineering Published:2020


Abstract

Over the past few decades, biomedical scientists and surgeons have given substantial attention to bioactive glasses as promising, long-lasting biomaterials that can make chemical connections with the neighboring hard and soft tissues. Several studies have examined the cellular and molecular responses to bioactive glasses to determine if they are suitable biomaterials for tissue engineering and regenerative medicine. In this regard, different ions and additives have been used recently to induce specific characteristics for selective cellular and molecular responses. This Review briefly describes foreign-body response mechanisms and the role of adsorbed proteins as the key players in starting interactions between cells and biomaterials. It then explains the physicochemical properties of the most common bioactive glasses, which have a significant impact on their cellular and molecular responses. It is expected that, with the development of novel strategies, the physiochemical properties of bioactive glasses can be engineered to precisely control proteins' adsorption and cellular functions after implantation. Copyright © 2019 American Chemical Society.
Related Docs
View other Related Docs
1. Bioactive Glasses: Where Are We and Where Are We Going?, Journal of Functional Biomaterials (2018)
2. Using Bioactive Glasses in the Management of Burns, Frontiers in Bioengineering and Biotechnology (2019)
3. Bioactive Glasses and Calcium Phosphates, Biomaterials for Oral and Dental Tissue Engineering (2017)
4. Bioactive Glasses: Sprouting Angiogenesis in Tissue Engineering, Trends in Biotechnology (2018)
5. A Critical Review on the Cellular and Molecular Interactions at the Interface of Zirconia-Based Biomaterials, Ceramics International (2018)
6. Biocompatibility of Alumina-Based Biomaterials–A Review, Journal of Cellular Physiology (2019)
7. Synthesis and Physico-Chemical Characterization of Fluoride (F)- a Nd Silver (Ag)-Substituted Sol-Gel Mesoporous Bioactive Glasses, Biomedical Glasses (2019)
8. Potential of Bioactive Glasses for Cardiac and Pulmonary Tissue Engineering, Materials (2017)
Experts (# of related papers)
View all Related Experts
Mahmoud Azami (8)
Nasrin Lotfibakhshaiesh (7)
Other Related Docs
9. Protein Adsorption on Polymers, Materials Today Communications (2018)
10. The Anti-Biofilm Activity of Nanometric Zinc Doped Bioactive Glass Against Putative Periodontal Pathogens: An in Vitro Study, Biomedical Glasses (2020)
11. Bioactive Glasses and Glass/Polymer Composites for Neuroregeneration: Should We Be Hopeful?, Applied Sciences (Switzerland) (2020)
12. Silver- and Fluoride-Containing Mesoporous Bioactive Glasses Versus Commonly Used Antibiotics: Activity Against Multidrug-Resistant Bacterial Strains Isolated From Patients With Burns, Burns (2016)
13. Functionalization and Surface Modifications of Bioactive Glasses (Bgs): Tailoring of the Biological Response Working on the Outermost Surface Layer, Materials (2019)
14. Biomaterials for Regenerative Medicine: Historical Perspectives and Current Trends, Advances in Experimental Medicine and Biology (2018)
15. Mesoporous Bioactive Glasses: Promising Platforms for Antibacterial Strategies, Acta Biomaterialia (2018)
16. Optimization of Fluoride-Containing Bioactive Glasses As a Novel Scolicidal Agent Adjunct to Hydatid Surgery, Acta Tropica (2015)
17. Biological Response to Carbon-Family Nanomaterials: Interactions at the Nano-Bio Interface, Frontiers in Bioengineering and Biotechnology (2019)
18. Bone Tissue Engineering Using Human Cells: A Comprehensive Review on Recent Trends, Current Prospects, and Recommendations, Applied Sciences (Switzerland) (2019)
19. Comparison of the Antibacterial Effects of a Short Cationic Peptide and 1% Silver Bioactive Glass Against Extensively Drug-Resistant Bacteria, Pseudomonas Aeruginosa and Acinetobacter Baumannii, Isolated From Burn Patients, Amino Acids (2018)
20. A Comparative Investigation on Bioactivity and Antibacterial Properties of Sol-Gel Derived 58S Bioactive Glass Substituted by Ag and Zn, Silicon (2019)
21. Bioactive Glasses Entering the Mainstream, Drug Discovery Today (2018)
22. When Size Matters: Biological Response to Strontium- and Cobalt-Substituted Bioactive Glass Particles, Materials Today: Proceedings (2018)
23. Synthesis, Characterization and in Vitro Bioactivity of Mesoporous Copper Silicate Bioactive Glasses, Ceramics International (2018)
24. Synergistic Combination of Bioactive Glasses and Polymers for Enhanced Bone Tissue Regeneration, Materials Today: Proceedings (2018)
25. Effects of the Biological Environment on Ceramics: Degradation, Cell Response, and in Vivo Behavior, Fundamental Biomaterials: Ceramics (2018)
26. Nanostructured Monticellite for Tissue Engineering Applications - Part I: Microstructural and Physicochemical Characteristics, Ceramics International (2018)
27. Targeted Drug Delivery Based on Gold Nanoparticle Derivatives, Current Pharmaceutical Design (2017)
28. Effect of Nano-Bioactive Glass on Flexural Strength and Antimicrobial Activity of Resin-Modified Glass Ionomer Cement Containing 58S Nano-Bioactive Glass, Open Dentistry Journal (2022)
29. Acceleration of Bone Regeneration in Bioactive Glass/Gelatin Composite Scaffolds Seeded With Bone Marrow-Derived Mesenchymal Stem Cells Over-Expressing Bone Morphogenetic Protein-7, Materials Science and Engineering C (2017)
30. Biomedical Applications of Nanoceria: New Roles for an Old Player, Nanomedicine (2018)
31. Nano-Immunoengineering: Opportunities and Challenges, Current Opinion in Biomedical Engineering (2019)
32. Stimulation of Osteogenic Differentiation of Induced Pluripotent Stem Cells (Ipscs) Using Bioactive Glasses: An in Vitro Study, Frontiers in Bioengineering and Biotechnology (2019)
33. Optimisation and Biological Activities of Bioceramic Robocast Scaffolds Provided With an Oxygen-Releasing Coating for Bone Tissue Engineering Applications, Ceramics International (2019)
34. A Meta-Analysis Review of the Effect of Zn-Doped Synthetic Polymer Materials on Bone Regeneration, Journal of Drug Delivery Science and Technology (2022)
35. Synthesis and Characterization of Novel Mesoporous Strontium-Modified Bioactive Glass Nanospheres for Bone Tissue Engineering Applications, Microporous and Mesoporous Materials (2020)
36. Kaempferol-Loaded Bioactive Glass-Based Scaffold for Bone Tissue Engineering: In Vitro and in Vivo Evaluation, Scientific Reports (2023)
37. Mesoporous Bioactive Glasses (Mbgs) in Cancer Therapy: Full of Hope and Promise, Materials Letters (2019)
38. Nanostructured Monticellite for Tissue Engineering Applications – Part Ii: Molecular and Biological Characteristics, Ceramics International (2018)
39. Synthesis, Characterization and in Vitro Biological Evaluation of Sol-Gel Derived Sr-Containing Nano Bioactive Glass, Silicon (2017)
40. Bone Regeneration in Rat Using a Gelatin/Bioactive Glass Nanocomposite Scaffold Along With Endothelial Cells (Huvecs), International Journal of Applied Ceramic Technology (2018)
41. Exploring the Various Effects of Cu Doping in Hydroxyapatite Nanoparticle, Scientific Reports (2024)
42. Osteogenic Potential of Stem Cells-Seeded Bioactive Nanocomposite Scaffolds: A Comparative Study Between Human Mesenchymal Stem Cells Derived From Bone, Umbilical Cord Wharton's Jelly, and Adipose Tissue, Journal of Biomedical Materials Research - Part B Applied Biomaterials (2018)
43. Biological Evaluation of Porous Nanocomposite Scaffolds Based on Strontium Substituted Β-Tcp and Bioactive Glass: An in Vitro and in Vivo Study, Materials Science and Engineering C (2019)
44. Nanostructured Monticellite: An Emerging Player in Tissue Engineering, Materials Today: Proceedings (2018)
45. Preparation and Characterization of Highly Porous Ceramic-Based Nanocomposite Scaffolds With Improved Mechanical Properties Using the Liquid Phase-Assisted Sintering Method, Proceedings of the Institution of Mechanical Engineers# Part L: Journal of Materials: Design and Applications (2019)
46. Strontium- and Cobalt-Substituted Bioactive Glasses Seeded With Human Umbilical Cord Perivascular Cells to Promote Bone Regeneration Via Enhanced Osteogenic and Angiogenic Activities, Acta Biomaterialia (2017)
47. Decellularized Human Amniotic Membrane: More Is Needed for an Efficient Dressing for Protection of Burns Against Antibiotic-Resistant Bacteria Isolated From Burn Patients, Burns (2015)
48. Metronidazole-Loaded Glass Ionomer Dental Cements, International Journal of Applied Ceramic Technology (2020)
49. Osteoblast-Seeded Bioglass/Gelatin Nanocomposite: A Promising Bone Substitute in Critical-Size Calvarial Defect Repair in Rat, International Journal of Artificial Organs (2016)
50. Resin-Based Sealant Containing Sol–Gel Derived Bioactive Glass: Ion Release and Biological Response, Journal of Sol-Gel Science and Technology (2023)