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Antibiotic Resistance Pattern of Helicobacter Pylori Strains Isolated From Patients in Isfahan, Iran Publisher



Sadeghi H1 ; Narimani T2 ; Tabesh E3 ; Shafiee F4 ; Soltani R5, 6
Authors

Source: Journal of Research in Medical Sciences Published:2022


Abstract

Background: The objective of this study was to evaluate the antibiotic resistance pattern of Helicobacter pylori strains isolated from patients in Isfahan province. Materials and Methods: Gastric antrum biopsy specimens of patients undergoing endoscopy were cultured. The samples with the growth of H. pylori underwent antibiotic susceptibility test by disk diffusion method. Reaults: Of 96 samples, 50 samples (53%) were positive for H. pylori. The rates of antibiotic resistance were as follows: amoxicillin, 6%; azithromycin, 20%; furazolidone, 22%; levofloxacin, 16%; metronidazole, 20%; rifampin, 12%; and tetracycline, 22%. Conclusion: H. pylori strains in our area have high rates of resistance to azithromycin, levofloxacin, metronidazole, tetracycline, and furazolidone. © 2022 Journal of Research in Medical Sciences Published by Wolters Kluwer-Medknow.
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