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The Effect of Vitamin D Supplementation on Serum 25-Hydroxy Vitamin D in the Patients Undergoing Bariatric Surgery: A Systematic Review and Meta-Analysis of Randomized Clinical Trials Publisher Pubmed

Summary: Meta-analysis shows vitamin D supplements boost levels in bariatric surgery patients, preventing PTH rise without affecting calcium. #BariatricSurgery #VitaminD

Mokhtari Z1 ; Hosseini E1 ; Zaroudi M2 ; Gibson DL3 ; Hekmatdoost A4 ; Mansourian M5 ; Salehiabargouei A6 ; Faghihimani Z1 ; Askari G1
Authors

Source: Obesity Surgery Published:2022


Abstract

Currently, there is no consensus on the optimal vitamin D administration in bariatric patients. The present systematic review and meta-analysis were conducted to examine the effect of vitamin D supplements on serum level of 25(OH) vitamin D in the patients undergoing bariatric surgery (BS). Random model effects were used to estimate standardized mean difference (SMD) with a 95% confidence interval (CI). Nine clinical trials were included in the meta-analysis. Vitamin D supplementation in patients undergoing BS modestly improves vitamin D status (SMD, 0.53; 95% CI, 0.28, 0.77) particularly, in the dosages above 2850 IU/day and in the patients with BMI greater than 50 kg/m2. Vitamin D supplementation was associated with prevention of raising of the PTH serum concentration and without impact on serum calcium levels. © 2022, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
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