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Anti-Allergic Effects of Vitamin E in Allergic Diseases: An Updated Review Publisher Pubmed



Shams MH1, 2 ; Jafari R3 ; Eskandari N1 ; Masjedi M1 ; Kheirandish F4, 5 ; Ganjalikhani Hakemi M1 ; Ghasemi R1 ; Varzi AM2, 5 ; Sohrabi SM2 ; Baharvand PA6 ; Safari M7
Authors
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Authors Affiliations
  1. 1. Department of Immunology, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Department of Medical Immunology, School of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran
  3. 3. Faculty of Medicine, Shahroud University of Medical Sciences, Shahroud, Iran
  4. 4. Department of Medical Parasitology and Mycology, School of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran
  5. 5. Razi Herbal Medicines Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran
  6. 6. Department of English, School of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran
  7. 7. Department of Pediatrics, School of Medicines, Hamedan University of Medical Science, Hamedan, Iran

Source: International Immunopharmacology Published:2021


Abstract

Allergic diseases are caused by the immune system's response to innocent antigens called allergens. Recent decades have seen a significant increase in the prevalence of allergic diseases worldwide, which has imposed various socio-economic effects in different countries. Various factors, including genetic factors, industrialization, improved hygiene, and climate change contribute to the development of allergic diseases in many parts of the world. Moreover, changes in lifestyle and diet habits play pivotal roles in the prevalence of allergic diseases. Dietary changes caused by decreased intake of antioxidants such as vitamin E lead to the generation of oxidative stress, which is central to the development of allergic diseases. It has been reported in many articles that oxidative stress diverts immune responses to the cells associated with the pathogenesis of allergic diseases. The aim of this short review was to summarize current knowledge about the anti-allergic properties of vitamin E. © 2020 Elsevier B.V.
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