The Relationship Between Nutrients Intake and Preeclampsia in Pregnant Women



Goodarzi Khoigani M¹ ; Paknahad Z² ; Mardanian F³
Source: Journal of Research in Medical Sciences Published:2012

Abstract

BACKGROUND: This Study aimed to investigate the associations between macro-and micronutrients received in the first, second, and third trimesters and risk for preeclampsia considering demographic and reproductive characteristics and physical activity. METHODS: In this prospective cohort study, data was collected by filling a questionnaire through interviews with 700 pregnant women who had no parameters to affect pregnancy outcome (36 parameters). In addition, 48-hour dietary recalls were completed for eligible women at 11th-15th, 26th, and 34th-37th weeks of gestation. Physical activity was also assessed using a standard questionnaire. Data on 48-hour dietary recalls was analyzed using Nutrition-IV software. Data was analyzed in SPSS18 using t-test and logistic regression analysis. RESULTS: The mean value of received saturated fatty acids in the first trimester in subjects who experienced preeclampsia later in pregnancy was higher than the rest of the pregnant women (p = 0.045). Manganese intake in the third trimester was significantly less in preeclamptic subjects compared to the others (p = 0.026). Moreover, vitamin C, vitamin E, fiber, and carbohydrate intakes during the third trimester were significantly less among the women with preeclampsia compared to the rest of the studied population (p = 0.034, p = 0.049, p = 0.046, and p = 0.035, respectively). Higher manganese (OR: 0.88; 95% CI: 0.76-0.90), vitamin C (OR: 0.985; 95% CI: 0.98-0.99), vitamin E (OR: 0.99; 95% CI: 0.984-0.996), fiber (OR: 0.97; 95% CI: 0.96-0.98), saturated fatty acids (OR: 1.028; 95% CI: 1.02-1.036), and carbohydrate (OR: 0.98; 95% CI: 0.97-0.99) intake increased the chance of preeclampsia in pregnant women. CONCLUSIONS: The amounts of received saturated fat in the first trimester and manganese, vitamin C, vitamin E, fiber, and carbohydrate during the third trimester are significantly associated with preeclampsia.