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Treatment of Intraoperative Sinus Tachycardia With Neostigmine Methylsulfate



Behaeen K1 ; Soltanzadeh M2 ; Pourmehdi Z3 ; Habibabadi MR4
Authors
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Authors Affiliations
  1. 1. Ahvaz jundishapur university of medical sciences, Imam Khomeini hospital, Ahvaz, Iran
  2. 2. Ahwaz Jundishapur University of Medical sciences, Golestan Hospital, Ahvaz, Iran
  3. 3. Ahvaz jundishapur university of medical sciences, Razi hospital, Ahvaz, Iran
  4. 4. Department of Anesthesiology of ayatoahkashani Hospital, Esfahan University of Medical Sciences, Esfahan, Iran

Source: Life Science Journal Published:2012

Abstract

Background: Neostigmine is an anticholinestrase drug. Sometimes during operation, patient heart rate increased without known causes. Materials and Methods: We used intravenous neostigmine for control of sinus tachycardia during surgery. In this research 100 patients with class I, II ASA were selected within a period of time (29 months) for intraoperative treatment of sinus tachycardia. Results: The maximum effect of neostigmine in reducing heart rate were in 15 minutes after its injection with 29.3% and 29.4% reducing in heart rate of the patients with 1-12 y/o and 12-65 y/o respectively. Conclusion: The results of this study indicate intravenous injection of neostigmine in doses. o.o1mg/kg can be useful in reducing intraoperative unknown sinus tachycardia in patients with different ranges of age.
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