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Common Microbial Causes of Significant Bacteriuria and Their Antibiotic Resistance Pattern in the Isfahan Province of Iran Publisher Pubmed



Pezeshki Najafabadi M1 ; Dagoohian A1 ; Rajaie S1 ; Zarkeshesfahani SH2 ; Edalati M3
Authors
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Authors Affiliations
  1. 1. Mahdieh Medical Diagnostic Center Charity, Iran
  2. 2. Department of Biology, Faculty of Sciences, University of Isfahan, Isfahan, Iran
  3. 3. Department of Pathology, Medical School, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Journal of Chemotherapy Published:2018


Abstract

Urinary tract infections (UTIs) are considered the most common community-acquired infections worldwide, which have possible complications along with significant economic impact on national healthcare systems. The aim of this study was to identify the most common causes of significant bacteriuria and to assess their antimicrobial resistance pattern in the Isfahan province of Iran. In this cross-sectional study, 11,678 urine samples of the patients referred to Mahdieh Medical Diagnostic Centre Charity were examined over a period of 10 months (from September 2015 to June 2016). Among the cases, 6.85% were positive for bacteriuria (F/M = 11.3). Escherichia coli (62%) was the most frequently isolated bacteria, followed by Staphylococcus epidermidis (13.9%) and Staphylococcus aureus (6.8%). E. coli was more prevalent among patients with diabetes mellitus. E. coli isolates showed the highest resistance to nalidixic acid, Trimethoprim/Sulfamethoxazole and Cefixime. Our results revealed that broad-spectrum antibiotic resistance is frequent among isolated uropathogens in Isfahan, Iran. © 2018, © 2018 Edizioni Scientifiche per l'Informazione su Farmaci e Terapia.
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