Tehran University of Medical Sciences

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Faculty Members have conducted research related to the Recombinant Cd137-Fc, Its Synthesis, and Applications for Improving the Immune System Functions, Such As Tumor Immunotherapy and to Reduce the Inflammation Due to the Novel Coronavirus
Forough Golsaz Shirazi
Forough Golsaz Shirazi

Associate Professor of Medical Immunology

Department Pathobiology

School of Public Health

Tehran University of Medical Sciences

Related Documents
1. Preclinical Assessment of a Recombinant Rbd-Fc Fusion Protein As Sars-Cov-2 Candidate Vaccine, European Journal of Microbiology and Immunology (2024)
All Documents
1. Comparative Assessment of Four Virus Neutralization Assays for Detection of Sars-Cov-2 Neutralizing Antibodies, Analytical Biochemistry (2025)
2. Production and Characterization of Monoclonal Antibodies Against Hepatitis B E-Antigen and Their Potential Application for Development of Hbeag Detection Elisa, Biologicals (2025)
3. Clinico-Pathological and Prognostic Significance of a Combination of Tumor Biomarkers in Iranian Patients With Breast Cancer, Clinical Breast Cancer (2024)
4. Comparative Immunogenicity and Neutralization Potency of Four Approved Covid-19 Vaccines in Balb/C Mice, Iranian Journal of Immunology (2024)
5. High Purity and Recovery of Native Filamentous Hemagglutinin (Fha) From Bordetella Pertussis Using Affinity Chromatography, Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences (2024)
6. Preclinical Assessment of a Recombinant Rbd-Fc Fusion Protein As Sars-Cov-2 Candidate Vaccine, European Journal of Microbiology and Immunology (2024)
7. A Novel Fc-Engineered Anti-Her2 Bispecific Antibody With Enhanced Antitumor Activity, Journal of Immunotherapy (2023)
8. Characterization and Immunogenicity of a Novel Chimeric Hepatitis B Core-Virus Like Particles (Cvlps) Carrying Rotavirus Vp8*Protein in Mice Model, Virology (2023)
9. Comparison of Different Transient Gene Expression Systems for the Production of a New Humanized Anti-Her2 Monoclonal Antibody (Hersintuzumab), DARU# Journal of Pharmaceutical Sciences (2023)
10. Cross-Reactivity of Hbe Antigen-Specific Polyclonal Antibody With Hbc Antigen, Viral Immunology (2023)
11. Diagnostic Performance of a Novel Antigen-Capture Elisa for the Detection of Sars-Cov-2, Analytical Biochemistry (2023)
12. Novel Monoclonal Antibodies Specific for Human Ki67 and P53 Tumor Markers in Breast Cancer Tissue Samples, Iranian Journal of Immunology (2023)
13. Novel Mouse Monoclonal Antibodies Against Bordetella Pertussis Pertactin Antigen With Versatile Applications, Journal of Microbiological Methods (2023)
14. Potent Anti-Tumor Immune Response and Tumor Growth Inhibition Induced by Her2 Subdomain Fusion Protein in a Mouse Tumor Model, Journal of Cancer Research and Clinical Oncology (2023)
15. Sars-Cov-2 Nucleocapsid: Biological Functions and Implication for Disease Diagnosis and Vaccine Design, Reviews in Medical Virology (2023)
16. Cross Talk Between Hepatitis B Virus and Innate Immunity of Hepatocytes, Reviews in Medical Virology (2022)
17. Differential Tumor Inhibitory Effects Induced by Her3 Extracellular Subdomain-Specific Mouse Monoclonal Antibodies, Cancer Chemotherapy and Pharmacology (2022)
18. Epitope Mapping of Neutralising Anti-Sars-Cov-2 Monoclonal Antibodies: Implications for Immunotherapy and Vaccine Design, Reviews in Medical Virology (2022)
19. Generation and Characterization of Novel Diagnostic Mouse Monoclonal Antibodies Against Human Estrogen Receptor Alpha and Progesterone Receptor, Asian Pacific Journal of Cancer Prevention (2022)
20. Optimization of an Efficient Cell Culture Hepatitis B Infection System for Assessment of Hepatitis B Virus Neutralizing Monoclonal Antibodies, Iranian Journal of Immunology (2022)
21. Preclinical Assessment of Immunogenicity and Protectivity of Novel Ror1 Fusion Proteins in a Mouse Tumor Model, Cancers (2022)
22. A Novel Anti-Her2 Bispecific Antibody With Potent Tumor Inhibitory Effects in Vitro and in Vivo, Frontiers in Immunology (2021)
23. A Novel Tumor Inhibitory Hybridoma Monoclonal Antibody With Dual Specificity for Her3 and Her2, Current Research in Translational Medicine (2021)
24. Influence of Pattern Recognition Receptor Ligands on Induction of Innate Immunity and Control of Hepatitis B Virus Infection, Viral Immunology (2021)
25. Neutralization of Tetanus Toxin by a Novel Chimeric Monoclonal Antibody, Toxicon (2021)
26. Potent Synergistic Anti-Tumor Activity of a Novel Humanized Anti-Her2 Antibody Hersintuzumab in Combination With Trastuzumab in Xenograft Models, Investigational New Drugs (2021)
27. T-Cell Engager Antibodies Enable T Cells to Control Hbv Infection and to Target Hbsag-Positive Hepatoma in Mice, Journal of Hepatology (2021)
28. Contribution of Fc Fragment of Monoclonal Antibodies to Tetanus Toxin Neutralization, Neurotoxicity Research (2020)
29. Epitope Mapping of Tetanus Toxin by Monoclonal Antibodies: Implication for Immunotherapy and Vaccine Design, Neurotoxicity Research (2020)
30. Immunoreactivity Pattern of Monoclonal Antibodies Against Hepatitis B Vaccine With Global Hepatitis B Virus Genotypes, Clinica Chimica Acta (2020)
31. Inhibitory Effect of Polyclonal Antibodies Against Her3 Extracellular Subdomains on Breast Cancer Cell Lines, Asian Pacific Journal of Cancer Prevention (2020)
32. Characterization of Monoclonal and Polyclonal Antibodies Recognizing Prostate Specific Antigen: Implication for Design of a Sandwich Elisa, Avicenna Journal of Medical Biotechnology (2019)
33. Development of a Novel Inhibitory Chimeric Anti-Her2 Monoclonal Antibody, Iranian Journal of Immunology (2019)
34. Differential Effects of Inhibitory and Stimulatory Anti-Her2 Monoclonal Antibodies on Akt/Erk Signaling Pathways, Asian Pacific Journal of Cancer Prevention (2018)
35. Hersintuzumab: A Novel Humanized Anti-Her2 Monoclonal Antibody Induces Potent Tumor Growth Inhibition, Investigational New Drugs (2018)
36. Immune Function of Plasmacytoid Dendritic Cells, Natural Killer Cells, and Their Crosstalk in Hbv Infection, Reviews in Medical Virology (2018)
37. Inhibition of Tumor Growth by Mouse Ror1 Specific Antibody in a Syngeneic Mouse Tumor Model, Immunology Letters (2018)
38. Comparison of Various Classifications for Patients With Common Variable Immunodeficiency (Cvid) Using Measurement of B-Cell Subsets, Allergologia et Immunopathologia (2017)
39. Comparison of Various Classifications for Patients With Common Variable Immunodeficiency (Cvid) Using Measurement of B-Cell Subsets, Allergologia et Immunopathologia (2017)
40. Construction of a Hepatitis B Virus Neutralizing Chimeric Monoclonal Antibody Recognizing Escape Mutants of the Viral Surface Antigen (Hbsag), Antiviral Research (2017)
41. Epitope Mapping of Human Her2 Specific Mouse Monoclonal Antibodies Using Recombinant Extracellular Subdomains, Asian Pacific Journal of Cancer Prevention (2017)
42. Polyclonal Antibody Against Different Extracellular Subdomains of Her2 Induces Tumor Growth Inhibition in Vitro, Iranian Journal of Immunology (2017)
43. Analysis of Knowledge, Attitudes, and Prevalence of Hepatitis B and C Seromarkers Among Barbers in Tehran, Hepatitis Monthly (2016)
44. Hepatitis B Immunopathogenesis and Immunotherapy, Immunotherapy (2016)
45. Localization of Immunodominant Epitopes Within the “A” Determinant of Hepatitis B Surface Antigen Using Monoclonal Antibodies, Archives of Virology (2016)
46. Human Leukocyte Antigens Influence the Antibody Response to Hepatitis B Vaccine, Iranian Journal of Allergy# Asthma and Immunology (2015)
47. Molecular Characterization of Murine Monoclonal Antibody Variable Regions Specific for Hepatitis B Surface Antigen, Viral Immunology (2015)