Tehran University of Medical Sciences

Science Communicator Platform

Faculty Members have conducted research related to the Gene-Knocked Out Chimeric Antigen Receptor (Car) T Cells: Tuning up for the Next Generation Cancer Immunotherapy
Mahmood Naderi
Mahmood Naderi

Associate Professor of Medical Biotechnology

Digestive Diseases Research Center

Tehran University of Medical Sciences

Related Documents
1. Antigenic Targets of Car T Cell Therapy. a Retrospective View on Clinical Trials, Experimental Cell Research (2018)
All Documents
1. Endocrine Neoplasm Tumor Biobank As a Platform for Advancing Cancer Research: A Framework for Design, Collection, Processing, and Storage; [بانک تومور نئوپلاسم‌های غدد درون‌ریز، زیربنای نوآوری در تحقیقات سرطان: طراحی، جمع‌آوری، پردازش و ذخیره‌سازی], Iranian Journal of Diabetes and Metabolism (2026)
2. Continued Rise in the Incidence of Thyroid Cancer in Iran: True Increase or Overdiagnosis?, Journal of Diabetes and Metabolic Disorders (2025)
3. Immunohistochemical Analysis Reveals Increased Active Gsk3 and Inactive Pp2a Levels in Anaplastic Thyroid Cancer, Journal of Diabetes and Metabolic Disorders (2025)
4. Exploring the Inhibitory Potential of Xanthohumol on Mek1/2: A Molecular Docking and Dynamics Simulation Investigation, Research in Pharmaceutical Sciences (2024)
5. Decoding the Expression Pattern of Muc3a in Gastric Adenocarcinoma: Unveiling the Key to Successful Immunotherapy, Expert Opinion on Therapeutic Targets (2023)
6. Bi-847325, a Selective Dual Mek and Aurora Kinases Inhibitor, Reduces Aggressive Behavior of Anaplastic Thyroid Carcinoma on an in Vitro Three-Dimensional Culture, Cancer Cell International (2022)
7. Development of a Multiepitope Vaccine Against Sars-Cov-2: Immunoinformatics Study, JMIR Bioinformatics and Biotechnology (2022)
8. Interpatient Variability in Mesothelin Expression Necessitates Its Evaluation Before Gastric Cancer Immunotherapy, Immunotherapy (2022)
9. Long-Term Aerobic Exercise Training in Type Two Diabetic Patients Alters the Expression of Mirna-223 and Its Corresponding Target, the P2ry12 Receptor, Attenuating Platelet Function, Clinical Hemorheology and Microcirculation (2022)
10. Surface Modification of Titanium Implants Via Electrospinning of Sericin and Equisetum Arvense Enhances the Osteogenic Differentiation of Stem Cells, International Journal of Polymeric Materials and Polymeric Biomaterials (2022)
11. Synergistic Effect of Mir-9 Overexpression and Electrical Induction on Differentiation of Conjunctiva Mesenchymal Stem Cells Into Photoreceptor-Like Cells, International Journal of Artificial Organs (2022)
12. A Systems Biology Approach for Mirna-Mrna Expression Patterns Analysis in Rheumatoid Arthritis, Combinatorial Chemistry and High Throughput Screening (2021)
13. An Outlook on Antigen-Specific Adoptive Immunotherapy for Viral Infections With a Focus on Covid-19, Cellular Immunology (2021)
14. Isolation and Characterization of Mesenchymal Stem Cells-Derived Exosomes by Method of Ultracentrifuge and Polyethylene Glycol, Journal of Isfahan Medical School (2020)
15. Microrna-7 Promotes Neural Differentiation of Trabecular Meshwork Mesenchymal Stem Cell on Nanofibrous Scaffold, Journal of Cellular Biochemistry (2020)
16. Mirna-146A Improves Immunomodulatory Effects of Msc-Derived Exosomes in Rheumatoid Arthritis, Current Gene Therapy (2020)
17. The Potency of Hsa-Mir-9-1 Overexpression in Photoreceptor Differentiation of Conjunctiva Mesenchymal Stem Cells on a 3D Nanofibrous Scaffold, Biochemical and Biophysical Research Communications (2020)
18. Unfolded Protein Response-Mediated Modulation of Mesenchymal Stem Cells, IUBMB Life (2020)
19. Antxr1 (Tem8) Overexpression in Gastric Adenocarcinoma Makes the Protein a Potential Target of Immunotherapy, Cancer Immunology# Immunotherapy (2019)
20. Generation of Cd19-Targeted Chimeric Antigen Receptor T Cells, Archives of Iranian Medicine (2019)
21. Msln (Mesothelin), Antxr1 (Tem8), and Muc3a Are the Potent Antigenic Targets for Car T Cell Therapy of Gastric Adenocarcinoma, Journal of Cellular Biochemistry (2019)
22. Addressing Cancer Immunotherapy Research in Iran: Adoptive Cell Therapy on the Horizon, Cytotherapy (2018)
23. Aerobic Training Improves Platelet Function in Type 2 Diabetic Patients: Role of Microrna-130A and Gpiib, Acta Diabetologica (2018)
24. Antigenic Targets of Car T Cell Therapy. a Retrospective View on Clinical Trials, Experimental Cell Research (2018)
25. Directly Injected Native Bone-Marrow Stem Cells Cannot Incorporate Into Acetaminophen-Induced Liver Injury, Biologicals (2018)
26. Effects of Endurance Training on Hsa-Mir-223, P2ry Nd Platelet Function in Type 2 Diabetic Patients, Clinical Hemorheology and Microcirculation (2018)
27. Precision Medicine Approach to Anaplastic Thyroid Cancer: Advances in Targeted Drug Therapy Based on Specific Signaling Pathways, Acta Medica Iranica (2017)
28. Quantitative Assessment of Wilms Tumor 1 Expression by Real-Time Quantitative Polymerase Chain Reaction in Patients With Acute Myeloblastic Leukemia, Journal of Research in Medical Sciences (2017)
29. Two Triacylglycerol Pathway Genes, Ctdnep1 and Lpin1, Are Down-Regulated by Hsa-Mir-122-5P in Hepatocytes, Archives of Iranian Medicine (2017)
30. A New Design for Electrospinner Collecting Device Facilitates the Removal of Small Diameter Tubular Scaffolds and Paves the Way for Tissue Engineering of Capillaries, Experimental Cell Research (2016)
31. Antisense-Mir-21 Enhances Differentiation/Apoptosis and Reduces Cancer Stemness State on Anaplastic Thyroid Cancer, Tumor Biology (2016)
32. Cancer Stem-Like Cell Behavior in Anaplastic Thyroid Cancer: A Challenging Dilemma, Life Sciences (2016)
33. Stochastic Petri Net Modeling of Hypoxia Pathway Predicts a Novel Incoherent Feed-Forward Loop Controlling Sdf-1 Expression in Acute Kidney Injury, IEEE Transactions on Nanobioscience (2016)
34. Stochastic Petri Net Modeling of Hypoxia Pathway Predicts a Novel Incoherent Feed-Forward Loop Controlling Sdf-1 Expression in Acute Kidney Injury, IEEE Transactions on Nanobioscience (2016)
35. Bypassing the Need for Pre-Sensitization of Cancer Cells for Anticancer Trail Therapy With Secretion of Novel Cell Penetrable Form of Smac From Ha-Mscs As Cellular Delivery Vehicle, Tumor Biology (2015)
36. Bypassing the Need for Pre-Sensitization of Cancer Cells for Anticancer Trail Therapy With Secretion of Novel Cell Penetrable Form of Smac From Ha-Mscs As Cellular Delivery Vehicle, Tumor Biology (2015)
37. Mapk and Jak/Stat Pathways Targeted by Mir-23A and Mir-23B in Prostate Cancer: Computational and in Vitro Approaches, Tumor Biology (2015)
38. Isolation of Asian Endemic and Livestock Associated Clones of Methicillin Resistant Staphylococcus Aureus From Ocular Samples in Northeastern Iran, Iranian Journal of Microbiology (2013)
39. Genetic Analysis of a Vancomycin-Resistant Staphylococcus Aureus Strain Isolated in Iran, mBio (2012)
40. Genetic Characterization of a Vancomycin-Resistant Staphylococcus Aureus Isolate From the Respiratory Tract of a Patient in a University Hospital in Northeastern Iran, Journal of Clinical Microbiology (2012)