Isfahan University of Medical Sciences

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Faculty Members have conducted research related to the Innovative Approaches to Combat Antibiotic Resistance: Integrating Crispr/Cas9 and Nanoparticles Against Biofilm-Driven Infections
Hossein Fazeli
Hossein Fazeli

Professor of Microbiology

Department of Bacteriology and Virology, School of Medicine

Isfahan University of Medical Sciences

All Documents
1. Antibiotic-Potentiating Efficacy of Rosmarinus Officinalis L. to Combat Planktonic Cells, Biofilms, and Efflux Pump Activities of Extensively Drug-Resistant Acinetobacter Baumannii Clinical Strains, Frontiers in Pharmacology (2025)
2. Exploring the Genetic Diversity and the Association of Drug Resistance and Biofilm Production in Acinetobacter Baumannii Strains Isolated From Burn Wound Infections, Iranian Journal of Microbiology (2025)
3. Evaluation of Chlorogenic Acid and Carnosol for Anti-Efflux Pump and Anti-Biofilm Activities Against Extensively Drug-Resistant Strains of Staphylococcus Aureus and Pseudomonas Aeruginosa, Microbiology Spectrum (2024)
4. Novel Mutation in Efflux Pump Rv1258c (Tap) Gene in Drug Resistant Clinical Isolates of Mycobacterium Tuberculosis in Iran, Journal of Infection in Developing Countries (2024)
5. Evaluation of the Simultaneous Effects of Lactobacillus Delbrueckii and Lactobacillus Lactis on Biofilms of Isolates From Chronic Ulcer Infections With Multiple-Drug Resistance, Jundishapur Journal of Microbiology (2022)
6. Phenotypicand Genotypic Characterization of Clinical Isolates of Intracellular Adherent–Invasive Escherichia Coli Among Different Stages, Family History, and Treated Colorectal Cancer Patients in Iran, Frontiers in Cellular and Infection Microbiology (2022)
7. Resistance to First-Line Drugs in Clinical Isolates of Mycobacterium Tuberculosis in Isfahan, Journal of Isfahan Medical School (2022)
8. Significance of the Coexistence of Non-Codon 315 Katg, Inha, and Oxyr-Ahpc Intergenic Gene Mutations Among Isoniazid-Resistant and Multidrug-Resistant Isolates of Mycobacterium Tuberculosis: A Report of Novel Mutations, Pathogens and Global Health (2022)
9. Antimicrobial Susceptibility Pattern of Carbapenemase-Producing Gram-Negative Nosocomial Bacteria at Al Zahra Hospital, Isfahan, Iran, Iranian Journal of Microbiology (2021)
10. Determination of Capsular Serotypes, Antibiotic Susceptibility Pattern, and Molecular Mechanism of Erythromycin Resistance Among Clinical Isolates of Group B Streptococcus in Isfahan, Iran, Advanced Biomedical Research (2021)
11. Investigation of Carbapenem Resistant Acinetobacter Baumannii St2 in Iran, Acta Microbiologica et Immunologica Hungarica (2021)
12. Molecular Detection of Type Ii Toxin-Antitoxin Systems and Their Association With Antibiotic Resistance and Biofilm Formation in Clinical Acinetobacter Baumannii Isolates of Burn Patients, Journal of Mazandaran University of Medical Sciences (2021)
13. Molecular Study of Gardnerella Vaginalis Isolated From Vaginal Discharge of Women Referring to Gynecology Clinics in Chaharmahal and Bakhtiari, Iran, in 2017, Archives of Clinical Infectious Diseases (2021)
14. Prevalence, Population Structure, Distribution of Serotypes, Pilus Islands and Resistance Genes Among Erythromycin-Resistant Colonizing and Invasive Streptococcus Agalactiae Isolates Recovered From Pregnant and Non-Pregnant Women in Isfahan, Iran, BMC Microbiology (2021)
15. Recombinant C-Reactive Protein: A Potential Candidate for the Treatment of Cutaneous Leishmaniasis of Balb/C Mice Caused by Leishmania Major, Acta Parasitologica (2021)
16. The Prevalence of Adherent-Invasive Escherichia Coli and Its Association With Inflammatory Bowel Diseases: A Systematic Review and Meta-Analysis, Frontiers in Medicine (2021)
17. Characterization of Hypervirulent Extended-Spectrum Β-Lactamase-Producing Klebsiella Pneumoniae Among Urinary Tract Infections: The First Report From Iran, Infection and Drug Resistance (2020)
18. Effect of Cleaning Guidelines Implementation on Microbial Colony Count of Laparoscopic Instruments: A Study in a Public Hospital in Iran, Asian Journal of Endoscopic Surgery (2020)
19. Global Sequence Analysis and Expression of Azurin Gene in Different Clinical Specimens of Burn Patients With Pseudomonas Aeruginosa Infection, Infection and Drug Resistance (2020)
20. Influence of Heterologously Expressed Azurin From Pseudomonas Aeruginosa on the Adhesion and Invasion of Pathogenic Bacteria to the Caco-2 Cell Line, Probiotics and Antimicrobial Proteins (2020)
21. Molecular Characterization of Hospital- and Community-Acquired Streptococcus Agalactiae Isolates Among Nonpregnant Adults in Isfahan, Iran, Advanced Biomedical Research (2020)
22. Analysis of Antibacterial and Antibiofilm Activity of Purified Recombinant Azurin From Pseudomonas Aeruginosa, Iranian Journal of Microbiology (2019)
23. Apoptosis-Inducing Effect of Spiroaminopyrimidine Analogue in Nb4 Leukemia Cells Via Down-Regulation of Birc5 Expression, Experimental Oncology (2019)
24. Determination of Surface Proteins Profile, Capsular Genotyping, and Antibiotic Susceptibility Patterns of Group B Streptococcus Isolated From Urinary Tract Infection of Iranian Patients, BMC Research Notes (2019)
25. Effect of Incise Drape on Contamination Rate of Surgical Wound During Surgical Procedures of Lumbar Spine, Advanced Biomedical Research (2019)
26. First Prevalence of Metallo Beta-Lactamases Producing Enterobacteriacea in Iranian Cancer Patients, Annali di Igiene Medicina Preventiva e di Comunita (2019)
27. Rapid Differential Diagnosis of Vaginal Infections Using Gold Nanoparticles Coated With Specific Antibodies, Medical Microbiology and Immunology (2019)
28. Determination of Antibiotic Resistance Pattern and Prevalence of Oxa-Type Carbapenemases Among Acinetobacter Baumannii Clinical Isolates From Inpatients in Isfahan, Central Iran, Infezioni in Medicina (2018)
29. Evaluation of Microorganism Colonization on Laparoscopic Instruments After Surgery and Following Two Different Cleaning Methods, Journal of Isfahan Medical School (2018)
30. Frequency Determination of Carbapenem-Resistant Klebsiella Pneumoniae (Crkp) Isolated From Hospitals in Isfahan of Iran and Evaluation of Synergistic Effect of Colistin and Meropenem on Them, Cellular and Molecular Biology (2018)
31. Prevalence of Metallo-Beta-Lactamase Producing Acinetobacter Baumannii Isolated From Intensive Care Unit in Tertiary Care Hospitals, Annali di Igiene Medicina Preventiva e di Comunita (2018)
32. The Effect of Incise Drape on the Incidence of Surgical Site Infection Following Lumbar Spine Surgeries, Journal of Isfahan Medical School (2018)
33. Determination of Biofilm Formation Ability and Antibiotic Resistance of Acinetobacter Baumannii Strains Isolated From Patients With Burn Wound Infection, Journal of Isfahan Medical School (2017)
34. Evaluation of the Synergistic Effect of Tomatidine With Several Antibiotics Against Standard and Clinical Isolates of Staphylococcus Aureus, Enterococcus Faecalis, Pseudomonas Aeruginosa and Escherichia Coli, Iranian Journal of Pharmaceutical Research (2017)
35. Genetic Lineages of Mycobacterium Tuberculosis Isolates in Isfahan, Iran, Current Microbiology (2017)
36. Isolation of Bacteriophages Against Multidrug Resistant Acinetobacter Baumannii, Research in Pharmaceutical Sciences (2017)
37. Analysis of Dna Gyra Gene Mutation in Clinical and Environmental Ciprofloxacin-Resistant Isolates of Non-Tuberculous Mycobacteria Using Molecular Methods, Jundishapur Journal of Microbiology (2016)
38. Study on Prevalence, Antibiotic Susceptibility, and Tuf Gene Sequence-Based Genotyping of Species-Level of Coagulase-Negative Staphylococcus Isolated From Keratitis Caused by Using Soft Contact Lenses, Eye and Contact Lens (2016)
39. Antibiotic Resistance Patterns and Genetic Diversity in Clinical Isolates of Pseudomonas Aeruginosa Isolated From Patients of a Referral Hospital, Isfahan, Iran, Jundishapur Journal of Microbiology (2015)
40. Detection of New Delhi Metallo-Beta-Lactamase-1 (Ndm-1) in Carbapenem-Resistant Klebsiella Pneumoniae Isolated From a University Hospital in Iran, Hippokratia (2015)
41. Morphological and Bactericidal Effects of Amikacin, Meropenem and Imipenem on Pseudomonas Aeruginosa, Jundishapur Journal of Microbiology (2015)
42. Production of Ifn-Γ and Il-4 Against Intact Catalase and Constructed Catalase Epitopes of Helicobacter Pylori From T-Cells, Jundishapur Journal of Microbiology (2015)
43. The Determination of Metallo-Beta-Lactamase Enzymes Prevalence in Pseudomonas Aeruginosa Using Etest and Their Antibiogram Patterns in Kermanshah, Iran, Journal of Kerman University of Medical Sciences (2015)
44. Antimicrobial Activity of a Uv-Stable Bacteriocin-Like Inhibitory Substance (Blis) Produced by Enterococcus Faecium Strain Dsh20 Against Vancomycin-Resistant Enterococcus (Vre) Strains, Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi (2014)
45. Detection of Colistin Sensitivity in Clinical Isolates of Acinetobacter Baumannii in Iran, Journal of Research in Medical Sciences (2014)
46. Detection of Quinolone-Resistance Mutations of Parc Gene in Clinical Isolates of Acinetobacter Baumannii in Iran, Journal of Research in Medical Sciences (2014)
47. Effects of Lactobacillus Plantarum A7 With Probiotic Potential on Colon Cancer and Normal Cells Proliferation in Comparison With a Commercial Strain, Iranian Journal of Basic Medical Sciences (2014)
48. Frequency of Multi-Drug Resistance Acinetobacter Baumannii Isolates in Intensive Care Units (Icu) of Isfahan Hospitals, Iran, Via Molecular Method and Their Antimicrobial Resistance Patterns, Journal of Isfahan Medical School (2014)
49. Identification of Non-Tuberculosis Mycobacteria Isolates by Polymerase Chain Reaction-Restriction Enzyme Analysis of 360-Bp Fragment of Rpob Gene, Journal of Isfahan Medical School (2014)
50. Identification of the Most Common Pathogenic Bacteria in Patients With Suspected Sepsis by Multiplex Pcr, Journal of Infection in Developing Countries (2014)
51. Molecular Epidemiology and Mechanisms of Antimicrobial Resistance in Pseudomonas Aeruginosa Isolates Causing Burn Wound Infection in Iran, Journal of Chemotherapy (2014)
52. Morphological and Bactericidal Effects of Different Antibiotics on Helicobacter Pylori, Jundishapur Journal of Microbiology (2014)
53. Prevalence and Antibacterial Resistance of Coagulase Negative Staphylococci in Keratitis Infections Following the Use of Soft Contact Lenses, Journal of Isfahan Medical School (2014)
54. Risk Factors and Prevalence of High Resistant Acinetobacter Spp Among Hospitalized Patients, Journal of Research in Medical Sciences (2014)
55. The Effect of Isolated Bacteriophage on Multi-Drug Resistant (Mdr) Pseudomonas Aeruginosa, Journal of Isfahan Medical School (2014)
56. Assessment of Cage and Baba Mrna Expression During Morphological Conversion of Helicobacter Pylori From Spiral to Coccoid, Current Microbiology (2013)
57. Ethambutol-Susceptibility of Clinical and Environmental Atypical Mycobacteria Isolated From Isfahan, Iran, Journal of Isfahan Medical School (2013)
58. In-Vitro Effects of Copper Nanoparticles on Common Bacterial Strains Implicated in Nosocomial Infections, Journal of Isfahan Medical School (2013)
59. Isolation and Purification of an Ultraviolet-Stable Bacteriocin Produced by Enterococcus Faecium Strain Dsh20 Against Listeria Monocytogenes, Journal of Isfahan Medical School (2013)
60. Isolation of Asian Endemic and Livestock Associated Clones of Methicillin Resistant Staphylococcus Aureus From Ocular Samples in Northeastern Iran, Iranian Journal of Microbiology (2013)
61. Pattern of Antibiotic Resistance in Pesudomonas Aeruginosa Isolated From Intensive Care Unit, Isfahan, Iran, Journal of Isfahan Medical School (2013)
62. Physicians and Nurses' Awareness of Transmission and Prevention Methods of Congenital Cytomegalovirus Infection, Journal of Isfahan Medical School (2013)
63. Prevalence and Antibiotic Resistance Pattern of Acinetobacter Species Isolated From Al-Zahra Hospital in Isfahan, Iran, Journal of Isfahan Medical School (2013)
64. Prevalence of Rotavirus Gastroenteritis and Circulating Genotypes in Children With Acute Gastroenteritis Admitted in Imam Hossein Hospital, Isfahan, Iran; 2013, Journal of Isfahan Medical School (2013)
65. Resistance Pattern of Helicobacter Pylori Strains to Clarithromycin, Metronidazole, and Amoxicillin in Isfahan, Iran, Journal of Research in Medical Sciences (2013)
66. Detection of Morphotyping Characteristics Identification Antibiotic Resistance of Pseudomonas Aeruginosa Isolated Form Cystic Fibrosis Patient, Journal of Isfahan Medical School (2012)
67. Development of Pcr-Based Method for Detection of Enterobacteriaceae in Septicemia, Journal of Research in Medical Sciences (2012)
68. Drug Resistance Pattern of Pseudomonas Aeruginosa Strains Isolated From Cystic Fibrosis Patients at Isfahan Al Zahra Hospital, Iran (2009-2010), Iranian Journal of Microbiology (2012)
69. Genetic Analysis of a Vancomycin-Resistant Staphylococcus Aureus Strain Isolated in Iran, mBio (2012)
70. Genetic Characterization of a Vancomycin-Resistant Staphylococcus Aureus Isolate From the Respiratory Tract of a Patient in a University Hospital in Northeastern Iran, Journal of Clinical Microbiology (2012)
71. Hiv/Aids-Related Knowledge of Young Couples Attending Pre-Marriage Counseling Centers in Isfahan, Iran, Journal of Isfahan Medical School (2012)
72. Molecular Characterization of Environmental Non-Tuberculous Mycobacteria Using Pcr- Rflp Analysis of 441 Bp Heat Shock Protein 65 Fragments, Iranian Journal of Public Health (2012)
73. Pseudomonas Aeruginosa Infections in Patients, Hospital Means, and Personnel's Specimens, Journal of Research in Medical Sciences (2012)
74. Two Dimensional Structural Analysis and Expression of a New Staphylococcus Aureus Adhesin Based Fusion Protein, Iranian Journal of Basic Medical Sciences (2012)
75. Identification of Beta-Lactamase-Producing Pseudomonas Aeruginosa With Multiple Antibiotic Resistances, Journal of Isfahan Medical School (2011)
76. Phenotypic Characteristics and Antibiotic Resistance Patterns of Most Common Nosocomial Pathogens in Noor Hospital, Isfahan, Iran, Journal of Isfahan Medical School (2011)
77. Reduction in Serum Lipid Parameters by Incorporation of a Native Strain of Lactobacillus Plantarum A7 in Mice, Iranian Journal of Diabetes and Lipid Disorders (2010)
78. Synthesis, Antimicrobial Evaluation and Qsar Study of Some 3-Hydroxypyridine-4-One and 3-Hydroxypyran-4-One Derivatives, European Journal of Medicinal Chemistry (2009)
79. Enumeration of Lactobacilli in the Fecal Flora of Infant Using Two Different Modified De-Man Rogosa Sharpe Media Under Aerobic and Anaerobic Incubation, Pakistan Journal of Biological Sciences (2008)