Tehran University of Medical Sciences

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Faculty Members have conducted research related to the Neuroprotective and Anticonvulsant Effects of Sinomenine in Kainate Rat Model of Temporal Lobe Epilepsy: Involvement of Oxidative Stress, Inflammation and Pyroptosis
Javad Fahanik-Babaei
Javad Fahanik-Babaei

Assistant Professor of Pharmaceutical Sciences

Electrophysiology Research Center

Tehran University of Medical Sciences

All Documents
1. Erratum to Cognitive Impairments Induced by Repeated Sevoflurane Exposure During Pre-Adolescence in Adult Male and Female Rats: Involvement of Biochemical, Histological and Neuroplasticity Approaches (J Cell Mol Anesth. 2023; 8(4): E149757), Journal of Cellular and Molecular Anesthesia (2025)
2. 40 Hz Light Preserves Synaptic Plasticity and Mitochondrial Function in Alzheimer’S Disease Model, Scientific Reports (2024)
3. Acute Nicotine Exposure Attenuates Neurological Deficits, Ischemic Injury and Brain Inflammatory Responses and Restores Hippocampal Long-Term Potentiation in Ischemic Stroke Followed by Lipopolysaccharide-Induced Sepsis-Like State, Experimental Neurology (2024)
4. Characterization of a Novel Ca2+-Activated Potassium Channel in Rat Brain Rough Endoplasmic Reticulum, Archives of Biochemistry and Biophysics (2024)
5. Csf Amino Acid Profiles in Icv-Streptozotocin-Induced Sporadic Alzheimer's Disease in Male Wistar Rat: A Metabolomics and Systems Biology Perspective, FEBS Open Bio (2024)
6. Efficacy of Melatonin in Alleviating Disorders Arising From Repeated Exposure to Sevoflurane in Males and Females of the Wistar Rats During Preadolescence, Scientific Reports (2024)
7. Fasudil Attenuates Lipopolysaccharide-Induced Cognitive Impairment in C57bl/6 Mice Through Anti-Oxidative and Anti-Inflammatory Effects: Possible Role of Aquaporin-4, IBRO Neuroscience Reports (2024)
8. Kolaviron Neuroprotective Effect Against Okadaic Acid-Provoked Cognitive Impairment, Heliyon (2024)
9. Protective Effects of Licofelone on Scopolamine-Induced Spatial Learning and Memory Impairment by Enhancing Parkin-Dependent Mitophagy and Promotion of Neural Regeneration and in Adult Mice, European Journal of Pharmacology (2024)
10. The Effects of a Chalcone Derivative on Memory, Hippocampal Corticosterone and Bdnf Levels in Adult Rats, International Journal of Neuroscience (2024)
11. Aquaporin 4 Beyond a Water Channel; Participation in Motor, Sensory, Cognitive and Psychological Performances, a Comprehensive Review, Physiology and Behavior (2023)
12. Cognitive Impairments Induced by Repeated Sevoflurane Exposure During Pre-Adolescence in Adult Male and Female Rats: Involvement of Biochemical, Histological and Neuroplasticity Approaches, Journal of Cellular and Molecular Anesthesia (2023)
13. Endoplasmic Reticulum Stress Inhibition Ameliorated Wfs1 Expression Alterations and Reduced Pancreatic Islets’ Insulin Secretion Induced by High-Fat Diet in Rats, Scientific Reports (2023)
14. Pre- and Post-Treatment of Α-Tocopherol on Cognitive, Synaptic Plasticity, and Mitochondrial Disorders of the Hippocampus in Icv-Streptozotocin-Induced Sporadic Alzheimer’S-Like Disease in Male Wistar Rat, Frontiers in Neuroscience (2023)
15. Effects of Prenatal Exposure to Inflammation Coupled With Prepubertal Stress on Prefrontal White Matter Structure and Related Molecules in Adult Mouse Offspring, Metabolic Brain Disease (2022)
16. Maternal Stress Induced Endoplasmic Reticulum Stress and Impaired Pancreatic Islets’ Insulin Secretion Via Glucocorticoid Receptor Upregulation in Adult Male Rat Offspring, Scientific Reports (2022)
17. Paeonol Exerts Neuroprotective and Anticonvulsant Effects in Intrahippocampal Kainate Model of Temporal Lobe Epilepsy, Journal of Chemical Neuroanatomy (2022)
18. Preliminary Report of Iranian Registry of Alzheimer's Disease in Tehran Province: A Cross-Sectional Study in Iran, Health Science Reports (2022)
19. The 40-Hz White Light-Emitting Diode (Led) Improves the Structure–Function of the Brain Mitochondrial Katp Channel and Respiratory Chain Activities in Amyloid Beta Toxicity, Molecular Neurobiology (2022)
20. The Effect of 40-Hz White Led Therapy on Structure–Function of Brain Mitochondrial Atp-Sensitive Ca-Activated Large-Conductance Potassium Channel in Amyloid Beta Toxicity, Neurotoxicity Research (2022)
21. Ellagic Acid Ameliorates Neuroinflammation and Demyelination in Experimental Autoimmune Encephalomyelitis: Involvement of Nlrp3 and Pyroptosis, Journal of Chemical Neuroanatomy (2021)
22. Hepatocyte Growth Factor Attenuates the Severity of Status Epilepticus in Kainic Acid-Induced Model of Temporal Lobe Epilepsy by Targeting Apoptosis and Astrogliosis, Basic and Clinical Neuroscience (2021)
23. Intranasal Insulin Improves the Structure–Function of the Brain Mitochondrial Atp–Sensitive Ca2+ Activated Potassium Channel and Respiratory Chain Activities Under Diabetic Conditions, Biochimica et Biophysica Acta - Molecular Basis of Disease (2021)
24. A New Brain Mitochondrial Sodium-Sensitive Potassium Channel: Effect of Sodium Ions on Respiratory Chain Activity, Journal of Cell Science (2020)
25. Evaluation of the Ameliorative Effects of Oral Administration of Metformin on Epileptogenesis in the Temporal Lobe Epilepsy Model in Rats, Life Sciences (2020)
26. Neuroprotective and Anticonvulsant Effects of Sinomenine in Kainate Rat Model of Temporal Lobe Epilepsy: Involvement of Oxidative Stress, Inflammation and Pyroptosis, Journal of Chemical Neuroanatomy (2020)