Tehran University of Medical Sciences

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Faculty Members have conducted research related to the Gene Therapy Clinical Trials, Where Do We Go? an Overview
Naser Ahmadbeigi
Naser Ahmadbeigi

Associate Professor of Laboratory Hematology and Blood Banking

Tehran University of Medical Sciences

All Documents
1. Unwanted Disorders and Xenogeneic Graft-Versus-Host Disease in Experimental Immunodeficient Mice: How to Evaluate and How to Report, Animal Models and Experimental Medicine (2025)
2. A Review of Animal Models Utilized in Preclinical Studies of Approved Gene Therapy Products: Trends and Insights, Laboratory Animal Research (2024)
3. Clinicopathologic Effects of Xenogeneic Gvhd Induced by Adoptively Transferred Human-Derived T Cells in Severely Immunodeficient Mice, Archives of Iranian Medicine (2024)
4. Exploring Non-Viral Methods for the Delivery of Crispr-Cas Ribonucleoprotein to Hematopoietic Stem Cells, Stem Cell Research and Therapy (2024)
5. Gene Therapy in Glioblastoma Multiforme: Can It Be a Role Changer?, Heliyon (2024)
6. Challenges in Mesenchymal Stromal Cell-Based Therapies, Current Stem Cell Research and Therapy (2023)
7. Cytotoxicity of Wt1-Reactive T Cells Against Wilms Tumor: An Implication for Antigen-Specific Adoptive Immunotherapy, BioImpacts (2023)
8. Efficacy of Adoptively Transferred Allogeneic Cik Cells on Colorectal Cancer: Augmentative Antitumoral Effects of Gvhd, International Immunopharmacology (2023)
9. Engineering Chimeric Autoantibody Receptor T Cells for Targeted B Cell Depletion in Multiple Sclerosis Model: An In-Vitro Study, Heliyon (2023)
10. Regenerative Potential of Multinucleated Cells: Bone Marrow Adiponectin-Positive Multinucleated Cells Take the Lead, Stem Cell Research and Therapy (2023)
11. Regenerative Potential of Multinucleated Cells: Bone Marrow Adiponectin-Positive Multinucleated Cells Take the Lead, Stem Cell Research and Therapy (2023)
12. The Effect of Serum Origin on Cytokines Induced Killer Cell Expansion and Function, BMC Immunology (2023)
13. The Effect of Spion Size and Salting-Out on Transduction of Pegylated Lentiviral Vector, Journal of Ultrafine Grained and Nanostructured Materials (2023)
14. The Paths and Challenges of “Off-The-Shelf” Car-T Cell Therapy: An Overview of Clinical Trials, Biomedicine and Pharmacotherapy (2023)
15. Gene Therapy Clinical Trials, Where Do We Go? an Overview, Biomedicine and Pharmacotherapy (2022)
16. Retinal and Choroidal Neovascularization Antivascular Endothelial Growth Factor Treatments: The Role of Gene Therapy, Journal of Ocular Pharmacology and Therapeutics (2022)
17. An Outlook on Antigen-Specific Adoptive Immunotherapy for Viral Infections With a Focus on Covid-19, Cellular Immunology (2021)
18. Characterization of a Xenograft Model for Anti-Cd19 Car T Cell Studies, Clinical and Translational Oncology (2021)
19. In Vivo Study of the Angiogenesis Potential of Bone Marrow-Derived Mesenchymal Stem Cell Aggregates in Their Niche Like Environment, International Journal of Artificial Organs (2021)
20. In Vivo Study of the Angiogenesis Potential of Bone Marrow-Derived Mesenchymal Stem Cell Aggregates in Their Niche Like Environment, International Journal of Artificial Organs (2021)
21. Optimizing Interleukin-2 Concentration, Seeding Density and Bead-To-Cell Ratio of T-Cell Expansion for Adoptive Immunotherapy, BMC Immunology (2021)
22. Antigen-Independent Killer Cells Prepared for Adoptive Immunotherapy: One Source, Divergent Protocols, Diverse Nomenclature, Journal of Immunological Methods (2020)
23. Effects of Human Placenta-Derived Mesenchymal Stem Cells With Nk4 Gene Expression on Glioblastoma Multiforme Cell Lines, Journal of Cellular Biochemistry (2020)
24. Antxr1 (Tem8) Overexpression in Gastric Adenocarcinoma Makes the Protein a Potential Target of Immunotherapy, Cancer Immunology# Immunotherapy (2019)
25. Generation of Cd19-Targeted Chimeric Antigen Receptor T Cells, Archives of Iranian Medicine (2019)
26. Impact of Various Culture Conditions on Ex Vivo Expansion of Polyclonal T Cells for Adoptive Immunotherapy, APMIS (2019)
27. Msln (Mesothelin), Antxr1 (Tem8), and Muc3a Are the Potent Antigenic Targets for Car T Cell Therapy of Gastric Adenocarcinoma, Journal of Cellular Biochemistry (2019)
28. Safety and Efficacy of Allogenic Placental Mesenchymal Stem Cells for Treating Knee Osteoarthritis: A Pilot Study, Cytotherapy (2019)
29. Strategies for Prevention and Treatment of Peritoneal Fibrosis: A Scientometric Study, International Journal of Preventive Medicine (2019)
30. Systemic Infusion of Autologous Adipose Tissue-Derived Mesenchymal Stem Cells in Peritoneal Dialysis Patients: Feasibility and Safety, Cell Journal (2019)
31. A Systematic Review of Preclinical Studies on Therapeutic Potential of Stem Cells or Stem Cells Products in Peritoneal Fibrosis, Minerva Urologica e Nefrologica (2018)
32. Addressing Cancer Immunotherapy Research in Iran: Adoptive Cell Therapy on the Horizon, Cytotherapy (2018)
33. Anti-Tumour Effects of Trail-Expressing Human Placental Derived Mesenchymal Stem Cells With Curcumin-Loaded Chitosan Nanoparticles in a Mice Model of Triple Negative Breast Cancer, Artificial Cells# Nanomedicine and Biotechnology (2018)
34. Antigenic Targets of Car T Cell Therapy. a Retrospective View on Clinical Trials, Experimental Cell Research (2018)
35. Directly Injected Native Bone-Marrow Stem Cells Cannot Incorporate Into Acetaminophen-Induced Liver Injury, Biologicals (2018)
36. Osteoconduction of Unrestricted Somatic Stem Cells on an Electrospun Polylactic-Co-Glycolic Acid Scaffold Coated With Nanohydroxyapatite, Cells Tissues Organs (2018)
37. Draft of Iranian National Guideline for Cell Therapy Manufacturing, Archives of Iranian Medicine (2017)
38. Draft of Iranian National Guideline for Cell Therapy Manufacturing, Archives of Iranian Medicine (2017)
39. A New Design for Electrospinner Collecting Device Facilitates the Removal of Small Diameter Tubular Scaffolds and Paves the Way for Tissue Engineering of Capillaries, Experimental Cell Research (2016)
40. A Three-Dimensional Scaffold-Based System for Modeling the Bone Marrow Tissue, Stem Cells and Development (2016)
41. Mesenchymal Stem Cells and Endothelial Cells: A Common Ancestor?, Archives of Iranian Medicine (2016)
42. A Simple and Cost-Effective Method for Isolation and Expansion of Human Fetal Pancreas Derived Mesenchymal Stem Cells, Archives of Iranian Medicine (2015)