Tehran University of Medical Sciences

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Faculty Members have conducted research related to the Inhibition of Orexin Receptor 1 Contributes to the Development of Morphine Dependence Via Attenuation of Camp Response Element-Binding Protein and Phospholipase Cβ3
Esmail Riahi
Esmail Riahi

Associate Professor of Physiology

Department Physiology

School of Medicine

Tehran University of Medical Sciences

All Documents
1. Deep Brain Stimulation of the Anterior Cingulate Cortex Reduces Opioid Addiction in Preclinical Studies, Scientific Reports (2025)
2. Opioid Reward and Deep Brain Stimulation of the Lateral Hypothalamic Area, Vitamins and Hormones (2025)
3. N-Acetylcysteine Attenuates Accumbal Core Neuronal Activity in Response to Morphine in the Reinstatement of Morphine Cpp in Morphine Extinguished Rats, Progress in Neuro-Psychopharmacology and Biological Psychiatry (2024)
4. Neuroprotective Effects of Mk-801 Against Cerebral Ischemia Reperfusion, Heliyon (2024)
5. Validation of Drug-Nondrug Choice Procedure to Model Maladaptive Behavioural Allocation to Opioid Use in Rats, Addiction Biology (2024)
6. A Wide Range of Deep Brain Stimulation of the Nucleus Accumbens Shell Time Independently Reduces the Extinction Period and Prevents the Reinstatement of Methamphetamine-Seeking Behavior in Rats, Life Sciences (2023)
7. Deep Brain Stimulation of the Lateral Hypothalamus to Block Morphine Reward: Does the Intensity of Stimulation Matter?, Behavioural Brain Research (2023)
8. Distinct Suppressing Effects of Deep Brain Stimulation in the Orbitofrontal Cortex on the Development, Extinction, and Reinstatement of Methamphetamine-Seeking Behaviors, Life Sciences (2023)
9. Restoring the Firing Activity of Ventral Tegmental Area Neurons by Lateral Hypothalamic Deep Brain Stimulation Following Morphine Administration in Rats, Physiology and Behavior (2023)
10. A Single Immediate Use of the Cathodal Transcranial Direct Current Stimulation Induces Neuroprotection of Hippocampal Region Against Global Cerebral Ischemia, Journal of Stroke and Cerebrovascular Diseases (2022)
11. Effects of Nano-Curcumin on Noise Stress-Induced Hippocampus-Dependent Memory Impairment: Behavioral and Electrophysiological Aspects, Pharmacological Reports (2022)
12. Protective Effects of Nanocurcumin Against Stress-Induced Deterioration in the Intestine, Stress (2022)
13. The Interaction Between Sexual Reward/ Deprivation and the Acquisition, Extinction and Reinstatement of Morphine-Seeking Behavior, Behavioural Brain Research (2022)
14. The Neuroprotective Effects of Transcranial Direct Current Stimulation on Global Cerebral Ischemia and Reperfusion Via Modulating Apoptotic Pathways, Brain Research Bulletin (2022)
15. Using Dual Polarities of Transcranial Direct Current Stimulation in Global Cerebral Ischemia and Its Following Reperfusion Period Attenuates Neuronal Injury, Metabolic Brain Disease (2022)
16. Assessing the Effect of Diazepam on Methamphetamine-Induced Seeking Behavior in Rats, Iranian Journal of Psychiatry and Behavioral Sciences (2021)
17. Deep Brain Stimulation of the Lateral Hypothalamus Facilitates Extinction and Prevents Reinstatement of Morphine Place Preference in Rats, Neuromodulation (2021)
18. Effect of Histone Acetylation on Maintenance and Reinstatement of Morphine-Induced Conditioned Place Preference and Δfosb Expression in the Nucleus Accumbens and Prefrontal Cortex of Male Rats, Behavioural Brain Research (2021)
19. Systemic Administration of N-Acetylcysteine During the Extinction Period and on the Reinstatement Day Decreased the Maintenance of Morphine Rewarding Properties in the Rats, Behavioural Brain Research (2021)
20. Deep Brain Stimulation of the Orbitofrontal Cortex Prevents the Development and Reinstatement of Morphine Place Preference, Addiction Biology (2020)
21. Gnrh Protective Effects Against Amyloid Β-Induced Cognitive Decline: A Potential Role of the 17Β-Estradiol, Molecular and Cellular Endocrinology (2020)
22. Inhibition of Brain 17Β-Estradiol Synthesis by Letrozole Induces Cognitive Decline in Male and Female Rats, Neurobiology of Learning and Memory (2020)
23. The Potential Role of the Orexin Reward System in Future Treatments for Opioid Drug Abuse, Brain Research (2020)
24. Preventing Morphine Reinforcement With High-Frequency Deep Brain Stimulation of the Lateral Hypothalamic Area, Addiction Biology (2019)
25. Does High-Frequency Deep Brain Stimulation in Dorsal Regions of the Ventral Striatum Impair Extinction of Morphine-Induced Place Preference?, Biological Psychiatry (2018)
26. Minocycline Increases Firing Rates of Accumbal Neurons and Modifies the Effects of Morphine on Neuronal Activity, Addiction Biology (2018)
27. The Incidence of Traumatic Brain Injury in Tehran, Iran, Brain Injury (2018)
28. Acute Sleep Deprivation Preconditions the Heart Against Ischemia/ Reperfusion Injury: The Role of Central Gaba-A Receptors, Iranian Journal of Basic Medical Sciences (2017)
29. Reply to Li, Xing-Huan and Zuo, Yun-Xia, Regarding Their Comment ‘Correspondence Letter to the Editor Regarding “Early Childhood Exposure to Short Periods of Sevoflurane Is Not Associated With Later, Lasting Cognitive Deficits”’, Paediatric Anaesthesia (2017)
30. Role of Basal Stress Hormones and Amygdala Dimensions in Stress Coping Strategies of Male Rhesus Monkeys in Response to a Hazard-Reward Conflict, Iranian Journal of Basic Medical Sciences (2017)
31. Early Childhood Exposure to Short Periods of Sevoflurane Is Not Associated With Later, Lasting Cognitive Deficits, Paediatric Anaesthesia (2016)
32. The Electrical Activity of Hippocampal Pyramidal Neuron Is Subjected to Descending Control by the Brain Orexin/Hypocretin System, Neurobiology of Learning and Memory (2015)