Flt3l Governs the Development of Partially Overlapping Hematopoietic Lineages in Humans and Mice

Flt3l Governs the Development of Partially Overlapping Hematopoietic Lineages in Humans and Mice Publisher Pubmed

Momenilandi M^{1, 2} ; Levy R^{1, 2, 3} ; Sobrino S^{4, 5} ; Li J^{6, 7} ; Lagreslepeyrou C^{2, 8} ; Esmaeilzadeh H^{9, 10} ; Fayand A^{1, 2, 11} ; Le Floch C^{1, 2} ; Guerin A^{12, 13} ; Mina ED^{12, 13} ; Shearer D^{6, 7} ; Delmonte OM¹⁴ ; Yatim A¹⁵ ; Mulder K^{16, 17} Show All Authors

Momenilandi M^{1, 2}
Levy R^{1, 2, 3}
Sobrino S^{4, 5}
Li J^{6, 7}
Lagreslepeyrou C^{2, 8}
Esmaeilzadeh H^{9, 10}
Fayand A^{1, 2, 11}
Le Floch C^{1, 2}
Guerin A^{12, 13}
Mina ED^{12, 13}
Shearer D^{6, 7}
Delmonte OM¹⁴
Yatim A¹⁵
Mulder K^{16, 17}
Mancini M^{18, 19}
Rinchai D¹⁵
Denis A⁵
Neehus AL^{1, 2}
Balogh K^{6, 7}
Brendle S^{6, 7, 20}
Roknizadeh H²¹
Changiashtiani M²²
Seeleuthner Y^{1, 2}
Deswarte C^{1, 2}
Bessot B^{2, 8}
Cremades C¹
Materna M^{1, 2}
Cederholm A²³
Ogishi M¹⁵
Philippot Q^{1, 2}
Beganovic O²⁴
Ackermann M^{25, 26, 27}
Wuyts M²⁸
Khan T²⁹
Fouere S³⁰
Herms F³¹
Chanal J³²
Palterer B¹⁴
Bruneau J³³
Molina TJ³³
Leclercmercier S³³
Pretet JL³⁴
Youssefian L³⁵
Vahidnezhad H^{36, 37, 38}
Parvaneh N³⁹
Claeys KG^{40, 41}
Schrijvers R⁴²
Luka M⁴³
Perot P⁴⁴
Fourgeaud J^{45, 46}
Nourrisson C^{47, 48}
Poirier P^{47, 48}
Jouanguy E^{1, 2, 15}
Boissondupuis S^{1, 2, 15}
Bustamante J^{1, 2, 15, 49}
Notarangelo LD¹⁴
Christensen N^{6, 7}
Landegren N^{23, 50}
Abel L^{1, 2, 15}
Marr N^{29, 51}
Six E⁸
Langlais D^{18, 19, 52}
Waterboer T⁵³
Ginhoux F^{16, 17}
Ma CS^{12, 13}
Tangye SG^{12, 13}
Meyts I^{54, 55}
Lachmann N^{25, 26, 27}
Hu J^{6, 7}
Shahrooei M^{28, 56}
Bossuyt X^{28, 57}
Casanova JL^{1, 2, 3, 15, 58}
Beziat V^{1, 2, 15}

Source: Cell Published:2024

Abstract

FMS-related tyrosine kinase 3 ligand (FLT3L), encoded by FLT3LG, is a hematopoietic factor essential for the development of natural killer (NK) cells, B cells, and dendritic cells (DCs) in mice. We describe three humans homozygous for a loss-of-function FLT3LG variant with a history of various recurrent infections, including severe cutaneous warts. The patients’ bone marrow (BM) was hypoplastic, with low levels of hematopoietic progenitors, particularly myeloid and B cell precursors. Counts of B cells, monocytes, and DCs were low in the patients’ blood, whereas the other blood subsets, including NK cells, were affected only moderately, if at all. The patients had normal counts of Langerhans cells (LCs) and dermal macrophages in the skin but lacked dermal DCs. Thus, FLT3L is required for B cell and DC development in mice and humans. However, unlike its murine counterpart, human FLT3L is required for the development of monocytes but not NK cells. © 2024 The Authors

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Style	Citing Format
MLA	Momenilandi M, et al.. "Flt3l Governs the Development of Partially Overlapping Hematopoietic Lineages in Humans and Mice." Cell, vol. 187, no. 11, 2024, pp. 2817-2837.e31.
APA	Momenilandi M, Levy R, Sobrino S, Li J, Lagreslepeyrou C, Esmaeilzadeh H, Fayand A, Le Floch C, Guerin A, Mina ED, Shearer D, Delmonte OM, Yatim A, Mulder K, Mancini M, Rinchai D, Denis A, Neehus AL, Balogh K, ... Beziat V (2024). Flt3l Governs the Development of Partially Overlapping Hematopoietic Lineages in Humans and Mice. Cell, 187(11), 2817-2837.e31.
Chicago	Momenilandi M, Levy R, Sobrino S, Li J, Lagreslepeyrou C, Esmaeilzadeh H, Fayand A, et al.. "Flt3l Governs the Development of Partially Overlapping Hematopoietic Lineages in Humans and Mice." Cell 187, no. 11 (2024): 2817-2837.e31.
Harvard	Momenilandi M et al. (2024) 'Flt3l Governs the Development of Partially Overlapping Hematopoietic Lineages in Humans and Mice', Cell, 187(11), pp. 2817-2837.e31.
Vancouver	Momenilandi M, Levy R, Sobrino S, Li J, Lagreslepeyrou C, Esmaeilzadeh H, et al.. Flt3l Governs the Development of Partially Overlapping Hematopoietic Lineages in Humans and Mice. Cell. 2024;187(11):2817-2837.e31.
BibTex	@article{ author = {Momenilandi M and Levy R and Sobrino S and Li J and Lagreslepeyrou C and Esmaeilzadeh H and Fayand A and Le Floch C and Guerin A and Mina ED and Shearer D and Delmonte OM and Yatim A and Mulder K and Mancini M and Rinchai D and Denis A and Neehus AL and Balogh K and Brendle S and Roknizadeh H and Changiashtiani M and Seeleuthner Y and Deswarte C and Bessot B and Cremades C and Materna M and Cederholm A and Ogishi M and Philippot Q and Beganovic O and Ackermann M and Wuyts M and Khan T and Fouere S and Herms F and Chanal J and Palterer B and Bruneau J and Molina TJ and Leclercmercier S and Pretet JL and Youssefian L and Vahidnezhad H and Parvaneh N and Claeys KG and Schrijvers R and Luka M and Perot P and Fourgeaud J and Nourrisson C and Poirier P and Jouanguy E and Boissondupuis S and Bustamante J and Notarangelo LD and Christensen N and Landegren N and Abel L and Marr N and Six E and Langlais D and Waterboer T and Ginhoux F and Ma CS and Tangye SG and Meyts I and Lachmann N and Hu J and Shahrooei M and Bossuyt X and Casanova JL and Beziat V}, title = {Flt3l Governs the Development of Partially Overlapping Hematopoietic Lineages in Humans and Mice}, journal = {Cell}, volume = {187}, number = {11}, pages = {2817-2837.e31}, year = {2024} }
RIS	TY - JOUR AU - Momenilandi M AU - Levy R AU - Sobrino S AU - Li J AU - Lagreslepeyrou C AU - Esmaeilzadeh H AU - Fayand A AU - Le Floch C AU - Guerin A AU - Mina ED AU - Shearer D AU - Delmonte OM AU - Yatim A AU - Mulder K AU - Mancini M AU - Rinchai D AU - Denis A AU - Neehus AL AU - Balogh K AU - Brendle S AU - Roknizadeh H AU - Changiashtiani M AU - Seeleuthner Y AU - Deswarte C AU - Bessot B AU - Cremades C AU - Materna M AU - Cederholm A AU - Ogishi M AU - Philippot Q AU - Beganovic O AU - Ackermann M AU - Wuyts M AU - Khan T AU - Fouere S AU - Herms F AU - Chanal J AU - Palterer B AU - Bruneau J AU - Molina TJ AU - Leclercmercier S AU - Pretet JL AU - Youssefian L AU - Vahidnezhad H AU - Parvaneh N AU - Claeys KG AU - Schrijvers R AU - Luka M AU - Perot P AU - Fourgeaud J AU - Nourrisson C AU - Poirier P AU - Jouanguy E AU - Boissondupuis S AU - Bustamante J AU - Notarangelo LD AU - Christensen N AU - Landegren N AU - Abel L AU - Marr N AU - Six E AU - Langlais D AU - Waterboer T AU - Ginhoux F AU - Ma CS AU - Tangye SG AU - Meyts I AU - Lachmann N AU - Hu J AU - Shahrooei M AU - Bossuyt X AU - Casanova JL AU - Beziat V TI - Flt3l Governs the Development of Partially Overlapping Hematopoietic Lineages in Humans and Mice JO - Cell VL - 187 IS - 11 SP - 2817 EP - 2837.e31 PY - 2024 ER -

Style

Citing Format

MLA

Momenilandi M, et al.. "Flt3l Governs the Development of Partially Overlapping Hematopoietic Lineages in Humans and Mice." Cell, vol. 187, no. 11, 2024, pp. 2817-2837.e31.

APA

Momenilandi M, Levy R, Sobrino S, Li J, Lagreslepeyrou C, Esmaeilzadeh H, Fayand A, Le Floch C, Guerin A, Mina ED, Shearer D, Delmonte OM, Yatim A, Mulder K, Mancini M, Rinchai D, Denis A, Neehus AL, Balogh K, ... Beziat V (2024). Flt3l Governs the Development of Partially Overlapping Hematopoietic Lineages in Humans and Mice. Cell, 187(11), 2817-2837.e31.

Chicago

Momenilandi M, Levy R, Sobrino S, Li J, Lagreslepeyrou C, Esmaeilzadeh H, Fayand A, et al.. "Flt3l Governs the Development of Partially Overlapping Hematopoietic Lineages in Humans and Mice." Cell 187, no. 11 (2024): 2817-2837.e31.

Harvard

Momenilandi M et al. (2024) 'Flt3l Governs the Development of Partially Overlapping Hematopoietic Lineages in Humans and Mice', Cell, 187(11), pp. 2817-2837.e31.

Vancouver

Momenilandi M, Levy R, Sobrino S, Li J, Lagreslepeyrou C, Esmaeilzadeh H, et al.. Flt3l Governs the Development of Partially Overlapping Hematopoietic Lineages in Humans and Mice. Cell. 2024;187(11):2817-2837.e31.

BibTex

@article{ author = {Momenilandi M and Levy R and Sobrino S and Li J and Lagreslepeyrou C and Esmaeilzadeh H and Fayand A and Le Floch C and Guerin A and Mina ED and Shearer D and Delmonte OM and Yatim A and Mulder K and Mancini M and Rinchai D and Denis A and Neehus AL and Balogh K and Brendle S and Roknizadeh H and Changiashtiani M and Seeleuthner Y and Deswarte C and Bessot B and Cremades C and Materna M and Cederholm A and Ogishi M and Philippot Q and Beganovic O and Ackermann M and Wuyts M and Khan T and Fouere S and Herms F and Chanal J and Palterer B and Bruneau J and Molina TJ and Leclercmercier S and Pretet JL and Youssefian L and Vahidnezhad H and Parvaneh N and Claeys KG and Schrijvers R and Luka M and Perot P and Fourgeaud J and Nourrisson C and Poirier P and Jouanguy E and Boissondupuis S and Bustamante J and Notarangelo LD and Christensen N and Landegren N and Abel L and Marr N and Six E and Langlais D and Waterboer T and Ginhoux F and Ma CS and Tangye SG and Meyts I and Lachmann N and Hu J and Shahrooei M and Bossuyt X and Casanova JL and Beziat V}, title = {Flt3l Governs the Development of Partially Overlapping Hematopoietic Lineages in Humans and Mice}, journal = {Cell}, volume = {187}, number = {11}, pages = {2817-2837.e31}, year = {2024} }

RIS

TY - JOUR
AU - Momenilandi M
AU - Levy R
AU - Sobrino S
AU - Li J
AU - Lagreslepeyrou C
AU - Esmaeilzadeh H
AU - Fayand A
AU - Le Floch C
AU - Guerin A
AU - Mina ED
AU - Shearer D
AU - Delmonte OM
AU - Yatim A
AU - Mulder K
AU - Mancini M
AU - Rinchai D
AU - Denis A
AU - Neehus AL
AU - Balogh K
AU - Brendle S
AU - Roknizadeh H
AU - Changiashtiani M
AU - Seeleuthner Y
AU - Deswarte C
AU - Bessot B
AU - Cremades C
AU - Materna M
AU - Cederholm A
AU - Ogishi M
AU - Philippot Q
AU - Beganovic O
AU - Ackermann M
AU - Wuyts M
AU - Khan T
AU - Fouere S
AU - Herms F
AU - Chanal J
AU - Palterer B
AU - Bruneau J
AU - Molina TJ
AU - Leclercmercier S
AU - Pretet JL
AU - Youssefian L
AU - Vahidnezhad H
AU - Parvaneh N
AU - Claeys KG
AU - Schrijvers R
AU - Luka M
AU - Perot P
AU - Fourgeaud J
AU - Nourrisson C
AU - Poirier P
AU - Jouanguy E
AU - Boissondupuis S
AU - Bustamante J
AU - Notarangelo LD
AU - Christensen N
AU - Landegren N
AU - Abel L
AU - Marr N
AU - Six E
AU - Langlais D
AU - Waterboer T
AU - Ginhoux F
AU - Ma CS
AU - Tangye SG
AU - Meyts I
AU - Lachmann N
AU - Hu J
AU - Shahrooei M
AU - Bossuyt X
AU - Casanova JL
AU - Beziat V
TI - Flt3l Governs the Development of Partially Overlapping Hematopoietic Lineages in Humans and Mice
JO - Cell
VL - 187
IS - 11
SP - 2817
EP - 2837.e31
PY - 2024
ER -

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Abstract