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Cardiogenetics: Genetics for Cardiologists Publisher



Rabbani B1 ; Esmaeili S1 ; Akbari B2, 3 ; Mahdieh N1, 4
Authors
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Authors Affiliations
  1. 1. Growth and Development Research Center, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Dept of Medical Biotechnology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran
  3. 3. Cardiovascular Research Center, Imam Ali Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran
  4. 4. Cardiogenetic Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran

Source: Journal of Knowledge and Health in Basic Medical Sciences Published:2022


Abstract

Cardiovascular disease (CVD) is the leading cause of death worldwide, accounting for more than 17.9 million deaths a year. Various factors are involved in the disease's development, including lifestyle, nutrition, environment, and genetic factors. Genetics is one of the main causes of CVD because of the familial accumulation of these diseases especially in countries with traditional cultures. As a result, cardiologists need to be aware of the genetic background of CVD and how to use genetic testing to diagnose and find therapeutic solutions. Here, the genetic basis of various CVDs, especially those with single-gene inheritance, diagnostic methods, and advanced genetic diagnostic techniques are reviewed. Also, for each disease, candidate genes, and molecular genetic techniques appropriately to diagnose are suggested and introduced. © 2022, Shahroud University of Medical Sciences. All rights reserved.
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