Fosfomycin: A Look at Its Various Aspects

Fosfomycin: A Look at Its Various Aspects Publisher

Tajik S¹ ; Shokri F² ; Rostamnezhad M³ ; Khoshnood S⁴ ; Mortazavi SM⁴ ; Sholeh M⁵ ; Kouhsari E^{6, 7}

Show Affiliations

1. Department of Endodontics, Faculty of Dentistry, Islamic Azad University, Khorasgan (Isfahan) Branch, Isfahan, Iran
2. Department of Medical Genetics, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
3. Department of Pharmaceutics, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
4. Student Research Committee, School of Medicine, Bam University of Medical Sciences, Bam, Iran
5. Department of Microbiology, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran
6. Clinical Microbiology Research Center, Ilam University of Medical Sciences, Ilam, Iran
7. Laboratory Sciences Research Center, Golestan University of Medical Sciences, Gorgan, Iran

Source: Gene Reports Published:2020

Abstract

Today, due to the emergence and spread of multidrug-resistant bacteria that have caused many therapeutic problems for the medical systems, and the lack of production of effective antibiotics in the commercial field in recent years, physicians are increasingly interested in using older antibiotics such as fosfomycin. Besides, because of the relatively low bacterial resistance to fosfomycin and its broad spectrum of action, it seems to be a molecule of therapeutic interest in the era of infection treatment. This antibiotic is still effective against many multidrug-resistant and extensively drug-resistant bacteria by inhibiting the early stages of the cell wall assembly. In this review, we summarize the currently available data regarding pharmacokinetics and pharmacodynamics, mechanism of action, oral and parenteral use, susceptibility breakpoints, antibacterial activity, mechanisms and epidemiology of resistance, and adverse effects of fosfomycin. © 2020

2. Evaluation of Fosfomycin Activity Against Extended Spectrum Beta Lactamase (Esbl) Producing Enterobacteriaceae Isolated From Three Centers of Tehran, Iran, Recent Patents on Anti-Infective Drug Discovery (2018)

3. Global Prevalence and Antibiotic Resistance in Clinical Isolates of Stenotrophomonas Maltophilia: A Systematic Review and Meta-Analysis, Frontiers in Medicine (2023)

Experts (# of related papers)

View all Related Experts

Mohammad Ali Boroumand (1)

Masoumeh Douraghi (1)

Style	Citing Format
MLA	Tajik S, et al.. "Fosfomycin: A Look at Its Various Aspects." Gene Reports, vol. 19, no. , 2020, pp. -.
APA	Tajik S, Shokri F, Rostamnezhad M, Khoshnood S, Mortazavi SM, Sholeh M, Kouhsari E (2020). Fosfomycin: A Look at Its Various Aspects. Gene Reports, 19(), -.
Chicago	Tajik S, Shokri F, Rostamnezhad M, Khoshnood S, Mortazavi SM, Sholeh M, Kouhsari E. "Fosfomycin: A Look at Its Various Aspects." Gene Reports 19, no. (2020): -.
Harvard	Tajik S et al. (2020) 'Fosfomycin: A Look at Its Various Aspects', Gene Reports, 19(), pp. -.
Vancouver	Tajik S, Shokri F, Rostamnezhad M, Khoshnood S, Mortazavi SM, Sholeh M, et al.. Fosfomycin: A Look at Its Various Aspects. Gene Reports. 2020;19():-.
BibTex	@article{ author = {Tajik S and Shokri F and Rostamnezhad M and Khoshnood S and Mortazavi SM and Sholeh M and Kouhsari E}, title = {Fosfomycin: A Look at Its Various Aspects}, journal = {Gene Reports}, volume = {19}, number = {}, pages = {-}, year = {2020} }
RIS	TY - JOUR AU - Tajik S AU - Shokri F AU - Rostamnezhad M AU - Khoshnood S AU - Mortazavi SM AU - Sholeh M AU - Kouhsari E TI - Fosfomycin: A Look at Its Various Aspects JO - Gene Reports VL - 19 IS - SP - EP - PY - 2020 ER -

Science Communicator Platform

Authors

Authors Affiliations

Abstract