A Facile and Efficient One-Pot Procedure for the Synthesis of Novel 2-Substituted 3-Thioxoisoindolin-1-One Derivatives

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):

Share By

A Facile and Efficient One-Pot Procedure for the Synthesis of Novel 2-Substituted 3-Thioxoisoindolin-1-One Derivatives Publisher

Gholami F¹ ; Moazzam A² ; Bahadorikhalili S² ; Adib M¹ ; Hosseini S³ ; Larijani B² ; Mahdavi M²

Source: Synlett Published:2022

Abstract

In this paper, a novel and efficient method is reported for the synthesis of novel 2-substituted 3-thioxoisoindolin-1-one derivatives. The method is based on the solvent-free reaction of 2-carboxybenzaldehyde with aliphatic amines and sulfur at 100 °C. This reaction is intensely significant, especially in pharmacy applications, due to the facile synthesis of asymmetric thioxoisoindolin-1-one derivatives with phthalimide backbones. © 2022 Georg Thieme Verlag. All rights reserved.

Related Docs

View other Related Docs

1. Facile Non-Transition Metal-Catalyzed Synthesis of 2-Thioxo-2,3-Dihydroquinazolin-4(1H)-One Derivatives Via One-Pot Multicomponent Reactions, ChemistrySelect (2019)

2. Synthesis of Novel 2-Oxoquinoline Derivatives Via Ugi-Four-Component-Heck Reaction, Journal of Heterocyclic Chemistry (2015)

3. Preparation of 1-Fluoro-4-Methyl-9H-[Carbonyl-14C]Thioxanthen-9-One and Amine Derivatives, Journal of Labelled Compounds and Radiopharmaceuticals (2016)

Experts (# of related papers)

View all Related Experts

Mohammad Mahdavi (7)

Bagher Larijani (4)

Other Related Docs

4. Recent Strategies in the Synthesis of Thiophene Derivatives: Highlights From the 2012–2020 Literature, Molecular Diversity (2021)

5. Amine-Carbon Disulfide Promoted Synthesis of Novel Benzo[E][1,3]Thiazepin-5(1H)-One Derivatives, Journal of Heterocyclic Chemistry (2020)

6. Cubr-Catalysed One-Pot Multicomponent Synthesis of 3-Substituted 2-Thioxo-2,3-Dihydroquinazolin-4(1H)-One Derivatives, Applied Organometallic Chemistry (2019)

7. C1-Functionalization of 1,2,3,4-Tetrahydroisoquinolines (Thiqs), Asian Journal of Organic Chemistry (2021)

8. Advances and Applications of 2-Alkynylbenzaldoxime As a Valuable Synthetic Framework for Synthesizing N-Heterocycles, Tetrahedron (2023)

Style	Citing Format
MLA	Gholami F, et al.. "A Facile and Efficient One-Pot Procedure for the Synthesis of Novel 2-Substituted 3-Thioxoisoindolin-1-One Derivatives." Synlett, vol. 33, no. 17, 2022, pp. 1729-1732.
APA	Gholami F, Moazzam A, Bahadorikhalili S, Adib M, Hosseini S, Larijani B, Mahdavi M (2022). A Facile and Efficient One-Pot Procedure for the Synthesis of Novel 2-Substituted 3-Thioxoisoindolin-1-One Derivatives. Synlett, 33(17), 1729-1732.
Chicago	Gholami F, Moazzam A, Bahadorikhalili S, Adib M, Hosseini S, Larijani B, Mahdavi M. "A Facile and Efficient One-Pot Procedure for the Synthesis of Novel 2-Substituted 3-Thioxoisoindolin-1-One Derivatives." Synlett 33, no. 17 (2022): 1729-1732.
Harvard	Gholami F et al. (2022) 'A Facile and Efficient One-Pot Procedure for the Synthesis of Novel 2-Substituted 3-Thioxoisoindolin-1-One Derivatives', Synlett, 33(17), pp. 1729-1732.
Vancouver	Gholami F, Moazzam A, Bahadorikhalili S, Adib M, Hosseini S, Larijani B, et al.. A Facile and Efficient One-Pot Procedure for the Synthesis of Novel 2-Substituted 3-Thioxoisoindolin-1-One Derivatives. Synlett. 2022;33(17):1729-1732.
BibTex	@article{ author = {Gholami F and Moazzam A and Bahadorikhalili S and Adib M and Hosseini S and Larijani B and Mahdavi M}, title = {A Facile and Efficient One-Pot Procedure for the Synthesis of Novel 2-Substituted 3-Thioxoisoindolin-1-One Derivatives}, journal = {Synlett}, volume = {33}, number = {17}, pages = {1729-1732}, year = {2022} }
RIS	TY - JOUR AU - Gholami F AU - Moazzam A AU - Bahadorikhalili S AU - Adib M AU - Hosseini S AU - Larijani B AU - Mahdavi M TI - A Facile and Efficient One-Pot Procedure for the Synthesis of Novel 2-Substituted 3-Thioxoisoindolin-1-One Derivatives JO - Synlett VL - 33 IS - 17 SP - 1729 EP - 1732 PY - 2022 ER -

Science Communicator Platform

Authors

Abstract