A Facile and Efficient One-Pot Procedure for the Synthesis of Novel 2-Substituted 3-Thioxoisoindolin-1-One Derivatives

A Facile and Efficient One-Pot Procedure for the Synthesis of Novel 2-Substituted 3-Thioxoisoindolin-1-One Derivatives Publisher

Gholami F¹ ; Moazzam A² ; Bahadorikhalili S² ; Adib M¹ ; Hosseini S³ ; Larijani B² ; Mahdavi M²

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1. School of Chemistry, College of Science, University of Tehran, Tehran, Iran
2. Endocrinology and Metabolism Research Centre, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, 11174, Iran
3. Shahid Beheshti University of Medical Sciences, Tehran, Iran

Source: Synlett Published:2022

Abstract

In this paper, a novel and efficient method is reported for the synthesis of novel 2-substituted 3-thioxoisoindolin-1-one derivatives. The method is based on the solvent-free reaction of 2-carboxybenzaldehyde with aliphatic amines and sulfur at 100 °C. This reaction is intensely significant, especially in pharmacy applications, due to the facile synthesis of asymmetric thioxoisoindolin-1-one derivatives with phthalimide backbones. © 2022 Georg Thieme Verlag. All rights reserved.

Style	Citing Format
MLA	Gholami F, et al.. "A Facile and Efficient One-Pot Procedure for the Synthesis of Novel 2-Substituted 3-Thioxoisoindolin-1-One Derivatives." Synlett, vol. 33, no. 17, 2022, pp. 1729-1732.
APA	Gholami F, Moazzam A, Bahadorikhalili S, Adib M, Hosseini S, Larijani B, Mahdavi M (2022). A Facile and Efficient One-Pot Procedure for the Synthesis of Novel 2-Substituted 3-Thioxoisoindolin-1-One Derivatives. Synlett, 33(17), 1729-1732.
Chicago	Gholami F, Moazzam A, Bahadorikhalili S, Adib M, Hosseini S, Larijani B, Mahdavi M. "A Facile and Efficient One-Pot Procedure for the Synthesis of Novel 2-Substituted 3-Thioxoisoindolin-1-One Derivatives." Synlett 33, no. 17 (2022): 1729-1732.
Harvard	Gholami F et al. (2022) 'A Facile and Efficient One-Pot Procedure for the Synthesis of Novel 2-Substituted 3-Thioxoisoindolin-1-One Derivatives', Synlett, 33(17), pp. 1729-1732.
Vancouver	Gholami F, Moazzam A, Bahadorikhalili S, Adib M, Hosseini S, Larijani B, et al.. A Facile and Efficient One-Pot Procedure for the Synthesis of Novel 2-Substituted 3-Thioxoisoindolin-1-One Derivatives. Synlett. 2022;33(17):1729-1732.
BibTex	@article{ author = {Gholami F and Moazzam A and Bahadorikhalili S and Adib M and Hosseini S and Larijani B and Mahdavi M}, title = {A Facile and Efficient One-Pot Procedure for the Synthesis of Novel 2-Substituted 3-Thioxoisoindolin-1-One Derivatives}, journal = {Synlett}, volume = {33}, number = {17}, pages = {1729-1732}, year = {2022} }
RIS	TY - JOUR AU - Gholami F AU - Moazzam A AU - Bahadorikhalili S AU - Adib M AU - Hosseini S AU - Larijani B AU - Mahdavi M TI - A Facile and Efficient One-Pot Procedure for the Synthesis of Novel 2-Substituted 3-Thioxoisoindolin-1-One Derivatives JO - Synlett VL - 33 IS - 17 SP - 1729 EP - 1732 PY - 2022 ER -

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