Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
What Kept Back on the Mirror of Covid-19-Related Acute Transverse Myelitis? a Genetic Background! Publisher



Sinaei R1, 2 ; Pezeshki S2, 3 ; Sinaei R1, 2
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Pediatrics, Kerman University of Medical Sciences, Kerman, Iran
  2. 2. Endocrinology and Metabolism Research Center, Institute of Basic and Clinical Physiology Sciences, Kerman University of Medical Sciences, Kerman, Iran
  3. 3. Department of Internal Medicine, Kerman University of Medical Sciences, Kerman, Iran
  4. 4. Department of Pediatric Neurology, Pediatrics Center of Excellence, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran

Source: Iranian Journal of Child Neurology Published:2023


Abstract

COVID-19-associated acute transverse myelitis (ATM) cases have been reported worldwide. Nevertheless, Iran, Italy, and the USA are the most affected countries, witnessing the possibility that genetic factors might be associated with this susceptibility. The genetic variants of the coronavirus-2 entry mechanisms and host innate immune response-related genes like interferons, interleukins, Toll-like receptors, human leukocyte antigens, blood groups, and some risk loci may be accountable. This study describes the compatibility of the geographical distribution between ATM and the Neanderthal core haplotype that confers risk for severe COVID-19 and some possible culprit genes. © 2023 The Authors.
Related Docs
1. Role of the Neanderthal Genome in Genetic Susceptibility to Covid-19: 3P21.31 Locus in the Spotlight, Biochemical Genetics (2024)
2. Stem Cell Therapy Potency in Personalizing Severe Covid-19 Treatment, Stem Cell Reviews and Reports (2021)
3. A Review of the Potential Neurological Adverse Events of Covid-19 Vaccines, Acta Neurologica Belgica (2023)
4. Human Genetic and Immunological Determinants of Critical Covid-19 Pneumonia, Nature (2022)
Experts (# of related papers)
Pantea Izadi (1)