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Nanomaterials Supported by Polymers for Tissue Engineering Applications: A Review Publisher



Habibzadeh F1 ; Sadraei SM1 ; Mansoori R2 ; Singh Chauhan NP3 ; Sargazi G4
Authors
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Authors Affiliations
  1. 1. Department of Medical Nanotechnology, Faculty of Advanced Technologies in Medicine, Iran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Medical Nanotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Department of Chemistry, Faculty of Science, Bhupal Nobles' University, Rajasthan, Udaipur, India
  4. 4. Noncommunicable Diseases Research Center, Bam University of Medical Sciences, Bam, Iran

Source: Heliyon Published:2022


Abstract

In the biomedical sciences, particularly in wound healing, tissue engineering, and regenerative medicine, the development of natural-based biomaterials as a carrier has revealed a wide range of advantages. Tissue engineering is one of the therapeutic approaches used to replace damaged tissue. Polymers have received a lot of attention for their beneficial interactions with cells, but they have some drawbacks, such as poor mechanical properties. Due to their relatively large surface area, nanoparticles can cause significant changes in polymers and improve their mechanical properties. The nanoparticles incorporated into biomaterial scaffolds have been associated with positive effects on cell adhesion, viability, proliferation, and migration in the majority of studies. This review paper discusses recent applications of polymer-nanoparticle composites in the development of tissue engineering scaffolds, as well as the effects of these nanomaterials in the fields of cardiovascular, neural, bone, and skin tissue engineering. © 2022 The Author(s)
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