Nanotechnology in Diagnosis and Treatment of Coronary Artery Disease

Nanotechnology in Diagnosis and Treatment of Coronary Artery Disease Publisher Pubmed

Karimi M¹ ; Zare H² ; Bakhshian Nik A³ ; Yazdani N² ; Hamrang M² ; Mohamed E² ; Zangabad PS⁴ ; Basri SMM^{5, 6} ; Bakhtiari L² ; Hamblin MR^{7, 8, 9}

Show Affiliations

1. Department of Medical Nanotechnology, Faculty of Advanced Technologies in Medicine, Iran University of Medical Sciences, Tehran, Iran
2. Biomaterials Group, Materials Science and Engineering Department, Iran University of Science and Technology, P.O. Box 1684613114, Tehran, Iran
3. Department of Life Science Engineering, Faculty of New Sciences and Technologies, University of Tehran, Tehran, 1439957131, Iran
4. Department of Materials Science and Engineering, Sharif University of Technology, P.O. Box 11365-9466, Tehran, 14588, Iran
5. School of Computer Science, Institute for Research in Fundamental Sciences, Tehran, Iran
6. Civil and Environmental Engineering Department, Shahid Beheshti University, Tehran, Iran
7. Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, 02114, MA, United States
8. Department of Dermatology, Harvard Medical School, Boston, 02115, MA, United States
9. Harvard-MIT Division of Health Sciences and Technology, Cambridge, 02139, MA, United States

Source: Nanomedicine Published:2016

Abstract

Nanotechnology could provide a new complementary approach to treat coronary artery disease (CAD) which is now one of the biggest killers in the Western world. The course of events, which leads to atherosclerosis and CAD, involves many biological factors and cellular disease processes which may be mitigated by therapeutic methods enhanced by nanotechnology. Nanoparticles can provide a variety of delivery systems for cargoes such as drugs and genes that can address many problems within the arteries. In order to improve the performance of current stents, nanotechnology provides different nanomaterial coatings, in addition to controlled-release nanocarriers, to prevent in-stent restenosis. Nanotechnology can increase the efficiency of drugs, improve local and systematic delivery to atherosclerotic plaques and reduce the inflammatory or angiogenic response after intravascular intervention. Nanocarriers have potential for delivery of imaging and diagnostic agents to precisely targeted destinations. This review paper will cover the current applications and future outlook of nanotechnology, as well as the main diagnostic methods, in the treatment of CAD. © 2016 Future Medicine Ltd.

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Style	Citing Format
MLA	Karimi M, et al.. "Nanotechnology in Diagnosis and Treatment of Coronary Artery Disease." Nanomedicine, vol. 11, no. 5, 2016, pp. 513-530.
APA	Karimi M, Zare H, Bakhshian Nik A, Yazdani N, Hamrang M, Mohamed E, Zangabad PS, Basri SMM, Bakhtiari L, Hamblin MR (2016). Nanotechnology in Diagnosis and Treatment of Coronary Artery Disease. Nanomedicine, 11(5), 513-530.
Chicago	Karimi M, Zare H, Bakhshian Nik A, Yazdani N, Hamrang M, Mohamed E, Zangabad PS, Basri SMM, Bakhtiari L, Hamblin MR. "Nanotechnology in Diagnosis and Treatment of Coronary Artery Disease." Nanomedicine 11, no. 5 (2016): 513-530.
Harvard	Karimi M et al. (2016) 'Nanotechnology in Diagnosis and Treatment of Coronary Artery Disease', Nanomedicine, 11(5), pp. 513-530.
Vancouver	Karimi M, Zare H, Bakhshian Nik A, Yazdani N, Hamrang M, Mohamed E, et al.. Nanotechnology in Diagnosis and Treatment of Coronary Artery Disease. Nanomedicine. 2016;11(5):513-530.
BibTex	@article{ author = {Karimi M and Zare H and Bakhshian Nik A and Yazdani N and Hamrang M and Mohamed E and Zangabad PS and Basri SMM and Bakhtiari L and Hamblin MR}, title = {Nanotechnology in Diagnosis and Treatment of Coronary Artery Disease}, journal = {Nanomedicine}, volume = {11}, number = {5}, pages = {513-530}, year = {2016} }
RIS	TY - JOUR AU - Karimi M AU - Zare H AU - Bakhshian Nik A AU - Yazdani N AU - Hamrang M AU - Mohamed E AU - Zangabad PS AU - Basri SMM AU - Bakhtiari L AU - Hamblin MR TI - Nanotechnology in Diagnosis and Treatment of Coronary Artery Disease JO - Nanomedicine VL - 11 IS - 5 SP - 513 EP - 530 PY - 2016 ER -

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