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Electrochemical Sensors and Biosensors Based on the Use of Polyaniline and Its Nanocomposites: A Review on Recent Advances Publisher Pubmed



Shoaie N1 ; Daneshpour M2 ; Azimzadeh M3, 4, 5 ; Mahshid S6 ; Khoshfetrat SM7, 8 ; Jahanpeyma F1 ; Gholaminejad A1 ; Omidfar K7, 8 ; Foruzandeh M1
Authors
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Authors Affiliations
  1. 1. Department of Biotechnology, Tarbiat Modares University of Medical Science, P.O. Box 14115-111, Tehran, Iran
  2. 2. Biotechnology Department, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, P.O. Box: 1985717443, Iran
  3. 3. Medical Nanotechnology & Tissue Engineering Research Center, Yazd Reproductive Sciences Institute, Shahid Sadoughi University of Medical Sciences, PO Box: 89195-999, Yazd, Iran
  4. 4. Stem Cell Biology Research Center, Yazd Reproductive Sciences Institute, Shahid Sadoughi University of Medical Sciences, Yazd, P.O. Box: 89195-999, Iran
  5. 5. Department of Advanced Medical Sciences and Technologies, School of Paramedicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
  6. 6. Department of Bioengineering, McGill University, P.O. Box: H3A 0E9, Montreal, QC, Canada
  7. 7. Biosensor Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Science, Tehran, P.O. Box:1411713137, Iran
  8. 8. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Research Institute, Tehran University of Medical Sciences, Tehran, Iran

Source: Microchimica Acta Published:2019


Abstract

Polyaniline and its composites with nanoparticles have been widely used in electrochemical sensor and biosensors due to their attractive properties and the option of tuning them by proper choice of materials. The review (with 191 references) describes the progress made in the recent years in polyaniline-based biosensors and their applications in clinical sensing, food quality control, and environmental monitoring. A first section summarizes the features of using polyaniline in biosensing systems. A subsequent section covers sensors for clinical applications (with subsections on the detection of cancer cells and bacteria, and sensing of glucose, uric acid, and cholesterol). Further sections discuss sensors for use in the food industry (such as for sulfite, phenolic compounds, acrylamide), and in environmental monitoring (mainly pesticides and heavy metal ions). A concluding section summarizes the current state, highlights some of the challenges currently compromising performance in biosensors and nanobiosensors, and discusses potential future directions. [Figure not available: see fulltext.]. © 2019, Springer-Verlag GmbH Austria, part of Springer Nature.
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