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One-Step Synthesis of Silver Nanostructures Using Heracleum Persicum Fruit Extract, Their Cytotoxic Activity, Anti-Cancer and Anti-Oxidant Activities Publisher



Dehnoee A1 ; Javad Kalbasi R1 ; Zangeneh MM2 ; Delnavazi MR3 ; Zangeneh A2
Authors
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Authors Affiliations
  1. 1. Faculty of Chemistry, Kharazmi University, Tehran, Iran
  2. 2. Biotechnology and Medicinal Plants Research Center, Ilam University of Medical Sciences, Ilam, Iran
  3. 3. Department of Pharmacognosy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran

Source: Micro and Nano Letters Published:2023


Abstract

Bio-inspired techniques are used for synthesis in terms of application, green chemical research, facile, and eco-friendly chemistry study of silver nanostructures utilizing plant extracts as natural reducing/stabilization and solid adjuvants without the use of toxic and damaging reagents. The present study investigates the biosynthesis of Ag nanoparticles via the mediation of the methanolic extract of Heracleum persicum seeds, without utilizing any stabilizer or surfactant. These nanostructures were identified utilizing ultraviolet–visible spectroscopy, field emission scanning electron microscopy, energy-dispersive X-ray spectroscopy, X-ray diffraction, high-resolution transmission electron microscopy, Fourier-transform infrared spectroscopy and dynamic light scattering. The attributes of AgNPs versus usual human breast adenocarcinoma cell lines that is, Hs 281.T, MDA-MB-468, AU565 [AU-565], MCF7, CAMA-1, SK-BR-3, NMU, and RBA were evaluated. The livability of breast adenocarcinoma cell line diminishes dose-dependently in the existence of AgNPs. After clinical studies, AgNPs can be used as a green drug in the treatment of human breast adenocarcinoma. © 2022 The Authors. Micro & Nano Letters published by John Wiley & Sons Ltd on behalf of The Institution of Engineering and Technology.
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