Gmp-Compliant Production of Human Placenta-Derived Mesenchymal Stem Cells

Gmp-Compliant Production of Human Placenta-Derived Mesenchymal Stem Cells Publisher Pubmed

Aghayan HR¹ ; Payab M² ; Mohamadijahani F³ ; Aghayan SS⁴ ; Larijani B⁵ ; Arjmand B^{1, 6}

Show Affiliations

1. Cell Therapy and Regenerative Medicine Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
2. Obesity and Eating Habits Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
3. Brain and Spinal Cord Injury Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran
4. Cell-Based Therapies Research Center, Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran
5. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
6. Metabolomics and Genomics Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran

Source: Methods in Molecular Biology Published:2021

Abstract

Mesenchymal stem cells are one of the most attractive sources for stem cell research and therapy. Their safety and efficacy have been demonstrated in many clinical trials. Because of their low immunogenicity and immunomodulatory properties, allogenic MSCs have been transplanted in different clinical studies. MSCs could be in different adult- and fetal-derived tissues including pregnancy products. Placenta-derived mesenchymal stem cells (PLMSCs) that can be harvested without using any invasive procedures from a discarding tissue are one of the important types of mesenchymal stem cells for therapeutic applications. Stem cell manufacturing for therapeutic applications should be in compliance with the basic principles of good manufacturing practice (GMP). Herein, the current chapter is to describe GMP-compliant production of human PLMSCs, which are suitable for clinical applications. © 2020, Springer Science+Business Media New York.

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Experts (# of related papers)

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Babak Arjmand (8)

Bagher Larijani (8)

Style	Citing Format
MLA	Aghayan HR, et al.. "Gmp-Compliant Production of Human Placenta-Derived Mesenchymal Stem Cells." Methods in Molecular Biology, vol. 2286, no. , 2021, pp. 213-225.
APA	Aghayan HR, Payab M, Mohamadijahani F, Aghayan SS, Larijani B, Arjmand B (2021). Gmp-Compliant Production of Human Placenta-Derived Mesenchymal Stem Cells. Methods in Molecular Biology, 2286(), 213-225.
Chicago	Aghayan HR, Payab M, Mohamadijahani F, Aghayan SS, Larijani B, Arjmand B. "Gmp-Compliant Production of Human Placenta-Derived Mesenchymal Stem Cells." Methods in Molecular Biology 2286, no. (2021): 213-225.
Harvard	Aghayan HR et al. (2021) 'Gmp-Compliant Production of Human Placenta-Derived Mesenchymal Stem Cells', Methods in Molecular Biology, 2286(), pp. 213-225.
Vancouver	Aghayan HR, Payab M, Mohamadijahani F, Aghayan SS, Larijani B, Arjmand B. Gmp-Compliant Production of Human Placenta-Derived Mesenchymal Stem Cells. Methods in Molecular Biology. 2021;2286():213-225.
BibTex	@article{ author = {Aghayan HR and Payab M and Mohamadijahani F and Aghayan SS and Larijani B and Arjmand B}, title = {Gmp-Compliant Production of Human Placenta-Derived Mesenchymal Stem Cells}, journal = {Methods in Molecular Biology}, volume = {2286}, number = {}, pages = {213-225}, year = {2021} }
RIS	TY - JOUR AU - Aghayan HR AU - Payab M AU - Mohamadijahani F AU - Aghayan SS AU - Larijani B AU - Arjmand B TI - Gmp-Compliant Production of Human Placenta-Derived Mesenchymal Stem Cells JO - Methods in Molecular Biology VL - 2286 IS - SP - 213 EP - 225 PY - 2021 ER -

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