Decorating and Loading Ghosts With Allergens for Allergen Immunotherapy

Decorating and Loading Ghosts With Allergens for Allergen Immunotherapy Publisher Pubmed

Fanuel S^{1, 2} ; Tabesh S³ ; Rajani HF¹ ; Heidari S⁴ ; Sadroddiny E¹ ; Kardar GA^{1, 2}

Show Affiliations

1. Department of Medical Biotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences-International Campus (IC-TUMS), Tehran, Iran
2. Immunology, Asthma & Allergy Research Institute (IAARI), Tehran University of Medical Sciences, Tehran, Iran
3. Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
4. Department of Immunology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran

Source: Human Vaccines and Immunotherapeutics Published:2017

Abstract

More than 25% of the global population has IgE mediated allergic diseases. Allergen immunotherapy (AIT) is the only available form of treatment that alters the underlying mechanism of IgE-mediated allergic diseases. AIT is aimed at desensitizing allergic individuals by repeatedly administering disease-causing allergens over a long period of time. Despite its proven efficacy in numerous clinical trials, the effectiveness of AIT still suffers some drawbacks due to the quality of allergens used and in particular the unavailability of efficient allergen delivery systems. Several studies have demonstrated that bacterial ghosts (BG) systems can be used to display and deliver antigens to their targets for the management of diseases. However, there is no report documenting the use of BG systems for immunotherapy of IgE-mediated diseases so far. Thus, in this review, we intend to discuss the potentialities of BG systems for displaying and delivering allergens for future management of IgE-mediated diseases. © 2017 Taylor & Francis.

2. A Comprehensive Overview of Allergen-Specific Immunotherapy Types, Recombinant and Natural Extract Allergens in the Diagnosis and Treatment of Allergies, Iranian Journal of Allergy# Asthma and Immunology (2022)

3. The Potential Use of Bacteria and Bacterial Derivatives As Drug Delivery Systems for Viral Infection, Virology Journal (2023)

Experts (# of related papers)

Mohammad Reza Fazlollahi (1)

Gholamali Kardar (1)

Style	Citing Format
MLA	Fanuel S, et al.. "Decorating and Loading Ghosts With Allergens for Allergen Immunotherapy." Human Vaccines and Immunotherapeutics, vol. 13, no. 10, 2017, pp. 2428-2433.
APA	Fanuel S, Tabesh S, Rajani HF, Heidari S, Sadroddiny E, Kardar GA (2017). Decorating and Loading Ghosts With Allergens for Allergen Immunotherapy. Human Vaccines and Immunotherapeutics, 13(10), 2428-2433.
Chicago	Fanuel S, Tabesh S, Rajani HF, Heidari S, Sadroddiny E, Kardar GA. "Decorating and Loading Ghosts With Allergens for Allergen Immunotherapy." Human Vaccines and Immunotherapeutics 13, no. 10 (2017): 2428-2433.
Harvard	Fanuel S et al. (2017) 'Decorating and Loading Ghosts With Allergens for Allergen Immunotherapy', Human Vaccines and Immunotherapeutics, 13(10), pp. 2428-2433.
Vancouver	Fanuel S, Tabesh S, Rajani HF, Heidari S, Sadroddiny E, Kardar GA. Decorating and Loading Ghosts With Allergens for Allergen Immunotherapy. Human Vaccines and Immunotherapeutics. 2017;13(10):2428-2433.
BibTex	@article{ author = {Fanuel S and Tabesh S and Rajani HF and Heidari S and Sadroddiny E and Kardar GA}, title = {Decorating and Loading Ghosts With Allergens for Allergen Immunotherapy}, journal = {Human Vaccines and Immunotherapeutics}, volume = {13}, number = {10}, pages = {2428-2433}, year = {2017} }
RIS	TY - JOUR AU - Fanuel S AU - Tabesh S AU - Rajani HF AU - Heidari S AU - Sadroddiny E AU - Kardar GA TI - Decorating and Loading Ghosts With Allergens for Allergen Immunotherapy JO - Human Vaccines and Immunotherapeutics VL - 13 IS - 10 SP - 2428 EP - 2433 PY - 2017 ER -

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