Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
The Effects of Spaced Transcranial Direct Current Stimulation Combined With Conventional Dysphagia Therapy in Parkinson’S Disease: A Case Report Publisher



Dashtelei AA1 ; Nitsche MA2, 3 ; Bakhtiari J4 ; Habibi SA5 ; Sepandi M6, 7 ; Khatoonabadi AR1
Authors
Show Affiliations
Authors Affiliations
  1. 1. Speech Therapy Department, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department Psychology and Neurosciences, Leibniz Research Centre for Working Environment and Human Factors, Dortmund, Germany
  3. 3. Department of Neurology, University Medical Hospital Bergmannsheil, Bochum, Germany
  4. 4. Speech Therapy Department, Semnan University of Medical Sciences, Tehran, Iran
  5. 5. Department of Neurology, Rasoul Akram Hospital, Iran University of Medical Science, Tehran, Iran
  6. 6. Department of Epidemiology and Biostatistics, Baqyiatallah University of Medical Science, Tehran, Iran
  7. 7. Health Research Center, Life Style Institute, Baqyiatallah University of Medical Science, Tehran, Iran

Source: EXCLI Journal Published:2020


Abstract

Parkinson's disease (PD) is a neurodegenerative disease of the central nervous system that is characterized by a set of motor and non-motor symptoms. Impaired swallowing or dysphagia is one relatively common motor symptom in patients with PD. We investigated whether neuroplasticity induction by spaced transcranial Direct Current Stimulation (tDCS) combined with conventional swallowing therapy leads to long-lasting effects on swallowing ability in patients with PD. We present a case of a 61-year-old male PD patient with dysphagia. Conventional Swallowing Therapy (CDT) combined with tDCS (bilateral anodal, 1 mA, 20 min, 10 online sessions, twice daily with a 20 min interval in between for five days over two weeks) was applied over the pharyngeal motor cortex. Our findings suggest that anodal tDCS combined with CDT is feasible, safe, and well-tolerated, and leads to a clinically relevant improvement of swallowing functions. © 2020, Leibniz Research Centre for Working Environment and Human Factors. All rights reserved.
Related Docs
1. Adjunctive Transcranial Direct Current Stimulation to Improve Swallowing Functions in Parkinson's Disease, EXCLI Journal (2024)
2. Transcranial Electrical and Magnetic Stimulation (Tes and Tms) for Addiction Medicine: A Consensus Paper on the Present State of the Science and the Road Ahead, Neuroscience and Biobehavioral Reviews (2019)
3. Closing the Loop Between Brain and Electrical Stimulation: Towards Precision Neuromodulation Treatments, Translational Psychiatry (2023)
4. Optimizing Electrode Montages of Transcranial Direct Current Stimulation for Attentional Bias Modification in Early Abstinent Methamphetamine Users, Frontiers in Pharmacology (2018)
5. Transcranial Electric Stimulation for Precision Medicine: A Spatiomechanistic Framework, Frontiers in Human Neuroscience (2017)
6. Fmri and Transcranial Electrical Stimulation (Tes): A Systematic Review of Parameter Space and Outcomes, Progress in Neuro-Psychopharmacology and Biological Psychiatry (2021)
7. A Checklist for Assessing the Methodological Quality of Concurrent Tes-Fmri Studies (Contes Checklist): A Consensus Study and Statement, Nature Protocols (2022)
Experts (# of related papers)
View all Related Experts
Ali Farhoudian (1)
Ahmad Reza Khatoonabadi (1)