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Covid-19 Cytokine Storm Complications in Asthmatic Patients Publisher



Nasab EM1 ; Athari SS2
Authors
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Authors Affiliations
  1. 1. Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Immunology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran

Source: Open Public Health Journal Published:2020


Abstract

The pandemic of coronavirus disease 2019 has inflicted millions of people in the world and caused severe complications in immunocompromised individuals. Some evidences suggest that severe COVID-19 complications are associated with the cytokine storm syndrome, contributing to the high mortality rate of the disease. Asthma is a complicated disease of the respiratory system. COVID-19 symptoms can be worse in asthmatic patients than others. Corticosteroids with anti-inflammatory functions which are used in asthmatic patients may have adverse outcomes in coronavirus infection and are not recommended for the treatment of COVID-19. Furthermore, asthmatic patients (using inhalation corticosteroids) have a suppressed immune system in the lung, which increases their susceptibility to COVID-19 infection. © 2020 Nasab & Athari.
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