Trigonella Teheranica: A Valuable Source of Phytochemicals With Antibacterial, Antioxidant and Cytotoxic Properties

Trigonella Teheranica: A Valuable Source of Phytochemicals With Antibacterial, Antioxidant and Cytotoxic Properties Publisher Pubmed

Kiashi F¹ ; Momeni Nasab F¹ ; Tavakoli S^{2, 3} ; Aghaahmadi M⁴ ; Goodarzi S² ; Pirali Hamedani M¹ ; Heidari F¹ ; Hadjiakhoondi A^{1, 2} ; Tofighi Z^{1, 2}

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1. Department of Pharmacognosy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
2. Medicinal Plants Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
3. Medicinal Plants Research Center, Institute of Medicinal Plants, ACECR, Alborz, Iran
4. Department of Biology, University of Isfahan, Isfahan, Iran

Source: Natural Product Research Published:2022

Abstract

Trigonella genus is a member of Fabaceae family, which is used as medicinal plant. The aim of this study was investigation of phytochemicals and some biological activities of Trigonella teheranica for the first time. The essential oils (EOs) of different parts (leaves, fruits and roots) were obtained and analyzed by GC-MS. Also, their chloroform and methanol extracts were prepared, too. The antimicrobial effects, antioxidant activities and cytotoxic effects against cancer (MDA-MB-231, MRC5 and HT-29) cell lines were investigated. N-hexadecanoic acid was the major compound of leaves and fruits EOs, and hexanal was abundant component of roots EO. The extracts showed stronger antibacterial effects than volatile oils against Gram-positive bacteria such as Staphylococcus aureus and Bacillus subtilis. All methanol extracts showed strong antioxidant effects, while the volatile oils, especially of leaves was the most effective in cytotoxic assay. Also, three derivatives of coumaric acid were isolated and identified from T. teheranica. © 2022 Informa UK Limited, trading as Taylor & Francis Group.

Style	Citing Format
MLA	Kiashi F, et al.. "Trigonella Teheranica: A Valuable Source of Phytochemicals With Antibacterial, Antioxidant and Cytotoxic Properties." Natural Product Research, vol. 36, no. 24, 2022, pp. 6405-6409.
APA	Kiashi F, Momeni Nasab F, Tavakoli S, Aghaahmadi M, Goodarzi S, Pirali Hamedani M, Heidari F, Hadjiakhoondi A, Tofighi Z (2022). Trigonella Teheranica: A Valuable Source of Phytochemicals With Antibacterial, Antioxidant and Cytotoxic Properties. Natural Product Research, 36(24), 6405-6409.
Chicago	Kiashi F, Momeni Nasab F, Tavakoli S, Aghaahmadi M, Goodarzi S, Pirali Hamedani M, Heidari F, Hadjiakhoondi A, Tofighi Z. "Trigonella Teheranica: A Valuable Source of Phytochemicals With Antibacterial, Antioxidant and Cytotoxic Properties." Natural Product Research 36, no. 24 (2022): 6405-6409.
Harvard	Kiashi F et al. (2022) 'Trigonella Teheranica: A Valuable Source of Phytochemicals With Antibacterial, Antioxidant and Cytotoxic Properties', Natural Product Research, 36(24), pp. 6405-6409.
Vancouver	Kiashi F, Momeni Nasab F, Tavakoli S, Aghaahmadi M, Goodarzi S, Pirali Hamedani M, et al.. Trigonella Teheranica: A Valuable Source of Phytochemicals With Antibacterial, Antioxidant and Cytotoxic Properties. Natural Product Research. 2022;36(24):6405-6409.
BibTex	@article{ author = {Kiashi F and Momeni Nasab F and Tavakoli S and Aghaahmadi M and Goodarzi S and Pirali Hamedani M and Heidari F and Hadjiakhoondi A and Tofighi Z}, title = {Trigonella Teheranica: A Valuable Source of Phytochemicals With Antibacterial, Antioxidant and Cytotoxic Properties}, journal = {Natural Product Research}, volume = {36}, number = {24}, pages = {6405-6409}, year = {2022} }
RIS	TY - JOUR AU - Kiashi F AU - Momeni Nasab F AU - Tavakoli S AU - Aghaahmadi M AU - Goodarzi S AU - Pirali Hamedani M AU - Heidari F AU - Hadjiakhoondi A AU - Tofighi Z TI - Trigonella Teheranica: A Valuable Source of Phytochemicals With Antibacterial, Antioxidant and Cytotoxic Properties JO - Natural Product Research VL - 36 IS - 24 SP - 6405 EP - 6409 PY - 2022 ER -

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