Autoantibodies Against Type I Ifns in Humans With Alternative Nf-Κb Pathway Deficiency

Autoantibodies Against Type I Ifns in Humans With Alternative Nf-Κb Pathway Deficiency Publisher Pubmed

Le Voyer T^{1, 2} ; Parent AV³ ; Liu X³ ; Cederholm A⁴ ; Gervais A^{1, 2} ; Rosain J^{1, 2, 5} ; Nguyen T^{6, 7} ; Perez Lorenzo M^{1, 2} ; Rackaityte E⁸ ; Rinchai D⁹ ; Zhang P⁹ ; Bizien L^{1, 2} ; Hancioglu G¹⁰ ; Ghillanidalbin P¹¹ Show All Authors

Le Voyer T^{1, 2}
Parent AV³
Liu X³
Cederholm A⁴
Gervais A^{1, 2}
Rosain J^{1, 2, 5}
Nguyen T^{6, 7}
Perez Lorenzo M^{1, 2}
Rackaityte E⁸
Rinchai D⁹
Zhang P⁹
Bizien L^{1, 2}
Hancioglu G¹⁰
Ghillanidalbin P¹¹
Charuel JL¹¹
Philippot Q^{1, 2}
Gueye MS^{1, 2}
Maglorius Renkilaraj MRL^{1, 2}
Ogishi M⁹
Soudee C^{1, 2}
Migaud M^{1, 2}
Rozenberg F¹²
Momenilandi M^{1, 2}
Riller Q¹³
Imberti L¹⁴
Delmonte OM¹⁵
Muller G^{16, 17}
Keller B^{17, 18}
Orrego J¹⁹
Franco Gallego WA¹⁹
Rubin T²⁰
Emiroglu M²¹
Parvaneh N²²
Eriksson D^{23, 24, 25}
Arandaguillen M²⁵
Berrios DI³
Vong L^{26, 27}
Katelaris CH²⁸
Mustillo P²⁹
Raedler J³⁰
Bohlen J^{1, 2}
Bengi Celik J³¹
Astudillo C^{32, 33}
Winter S³⁴
Boissondupuis S^{1, 2, 9}
Oksenhendler E⁷³
Okada S¹⁰⁹
Caluseriu O¹¹⁰
Ursini MV¹¹¹
Ballot E¹¹²
Lafarge G^{11, 87}
Freiberger T⁶⁶
Arangofranco CA^{1, 2}
Levy R^{1, 2, 52}
Aiuti A¹¹³
Almuhsen S¹¹⁴
Almulla F¹¹⁵
Andreakos E¹¹⁶
Arias AA^{9, 117, 118}
Feldman HB¹¹⁹
Bastard P^{1, 2, 9, 52}
Bondarenko A¹²⁰
Borghesi A¹²¹
Bousfiha AA¹²²
Brodin P¹²³
Bryceson Y¹²⁴
Casari G¹²⁵
Christodoulou J¹²⁶
Colobran R¹²⁷
Condinoneto A¹²⁸
Fellay J^{129, 130}
Flores C^{131, 132, 133}
Franco JL¹⁹
Haerynck F¹³⁴
Halwani R^{114, 135}
Hammarstrom L^{39, 40}
Heath JR¹³⁶
Hsieh EWY¹³⁷
Itan Y^{138, 139}
Kaja E¹⁴⁰
Kisand K¹⁴¹
Ku CL¹⁴²
Ling Y¹⁴³
Lau YL¹⁴⁴
Mansouri D¹⁴⁵
Meyts I^{146, 147}
Milner JD¹⁴⁸
Mogensen TH¹⁴⁹
Novelli A¹⁵⁰
Novelli G¹⁵¹
Okamoto K¹⁵²
Ozcelik T¹⁵³
De Diego RP¹⁵⁴
Pereztur J¹⁵⁵
Perlin DS¹⁵⁶
Prando C¹⁵⁷
Pujol A^{158, 159, 160}
Quintanamurci L¹⁶¹
Renia L^{163, 164}
Resnick I¹⁶⁵
Rodriguezgallego C^{133, 166}
Sanchoshimizu V^{167, 168}
Sediva A⁵⁵
Seppanen MRJ^{169, 170}
Shahrooei M⁷⁸
Shcherbina A¹⁷¹
Palacin PS¹⁷²
Pesole G¹⁷³
Spaan AN⁹
Su HC^{15, 41}
Tancevski I¹⁷⁴
Tayoun AA¹⁷⁵
Amara A¹⁷⁶
Gorochov G¹⁷⁷
Temel SG^{178, 179}
Thorball C¹³⁰
Tiberghien P¹⁸⁰
Trouillet Assant S^{38, 104}
Turvey S¹⁸¹
Uddin KMF¹⁸²
Uddin MJ^{183, 184}
Van De Beek D¹⁸⁵
Vidigal M¹⁸⁶
Vinh DC^{187, 188}
Von Bernuth H^{189, 190, 191}
Wauters J¹⁹²
Zatz M¹⁸⁶
Zhang SY^{1, 2, 9}
Ng LFP^{163, 164}
Mclean C³⁵
Guffroy A³⁶
Derisi JL^{8, 37}
Yu D³
Miller C³
Feng Y⁹
Guichard A³⁸
Beziat V^{1, 2, 9}
Bustamante J^{1, 2, 5, 9}
Panhammarstrom Q^{39, 40}
Zhang Y^{15, 41}
Rosen LB¹⁵
Holland SM¹⁵
Bosticardo M¹⁵
Kenney H¹⁵
Castagnoli R^{42, 43}
Slade CA^{44, 45, 46}
Boztug K^{47, 48, 49, 50}
Mahlaoui N^{51, 52}
Latour S³⁴
Abraham RS⁵³
Lougaris V⁵⁴
Hauck F³⁰
Atschekzei F⁵⁶
Sogkas G⁵⁶
Poli MC^{32, 33}
Slatter MA⁵⁷
Palterer B⁵⁸
Keller MD⁵⁹
Pinzoncharry A^{60, 61}
Sullivan A^{60, 61}
Droney L^{60, 61}
Suan D^{60, 62}
Wong M^{60, 62, 63}
Kane A^{7, 60, 64, 65}
Hu H^{60, 64, 65}
Ma C^{6, 7, 60}
Grombirikova H⁶⁶
Ciznar P⁶⁷
Dalal I⁶⁸
Aladjidi N⁶⁹
Hie M⁷⁰
Lazaro E⁷¹
Keles S⁷²
Malphettes M⁷³
Pasquet M⁷⁴
Maccari ME^{16, 75}
Meinhardt A⁷⁶
Ikinciogullari A⁷⁷
Shahrooei M⁷⁸
Celmeli F⁸⁰
Frosk P⁸¹
Goodnow CC^{6, 7, 60}
Gray PE^{60, 82}
Belot A^{83, 84, 85}
Kuehn HS⁸⁶
Rosenzweig SD⁸⁶
Miyara M^{11, 87}
Licciardi F⁸⁸
Servettaz A^{89, 90}
Barlogis V⁹¹
Le Guenno G⁹²
Herrmann VM⁹³
Kuijpers T⁹⁴
Ducoux G⁹⁵
Sarrotreynauld F⁹⁶
Schuetz C⁹⁷
Cunninghamrundles C⁹⁸
Rieuxlaucat F¹³
Tangye SG^{6, 7, 60}
Sobacchi C^{99, 100}
Doffinger R¹⁰¹
Warnatz K^{17, 18}
Grimbacher B^{16, 17}
Fieschi C^{73, 102}
Berteloot L¹⁰³
Bryant VL^{44, 45, 46}
Neven B⁵²
Abel L^{1, 2, 9}
Zhang Q^{1, 2, 9}
Boisson B^{1, 2, 9}
Cobat A^{1, 2, 9}
Jouanguy E^{1, 2, 9}
Kampe O¹⁰⁵
Roifman CM^{26, 27}
Landegren N^{4, 25}
Notarangelo LD¹⁵
Anderson MS^{3, 106}
Casanova JL^{1, 2, 9, 107, 108}
Puel A^{1, 2, 9}

Source: Nature Published:2023

Abstract

Patients with autoimmune polyendocrinopathy syndrome type 1 (APS-1) caused by autosomal recessive AIRE deficiency produce autoantibodies that neutralize type I interferons (IFNs)1,2, conferring a predisposition to life-threatening COVID-19 pneumonia3. Here we report that patients with autosomal recessive NIK or RELB deficiency, or a specific type of autosomal-dominant NF-κB2 deficiency, also have neutralizing autoantibodies against type I IFNs and are at higher risk of getting life-threatening COVID-19 pneumonia. In patients with autosomal-dominant NF-κB2 deficiency, these autoantibodies are found only in individuals who are heterozygous for variants associated with both transcription (p52 activity) loss of function (LOF) due to impaired p100 processing to generate p52, and regulatory (IκBδ activity) gain of function (GOF) due to the accumulation of unprocessed p100, therefore increasing the inhibitory activity of IκBδ (hereafter, p52LOF/IκBδGOF). By contrast, neutralizing autoantibodies against type I IFNs are not found in individuals who are heterozygous for NFKB2 variants causing haploinsufficiency of p100 and p52 (hereafter, p52LOF/IκBδLOF) or gain-of-function of p52 (hereafter, p52GOF/IκBδLOF). In contrast to patients with APS-1, patients with disorders of NIK, RELB or NF-κB2 have very few tissue-specific autoantibodies. However, their thymuses have an abnormal structure, with few AIRE-expressing medullary thymic epithelial cells. Human inborn errors of the alternative NF-κB pathway impair the development of AIRE-expressing medullary thymic epithelial cells, thereby underlying the production of autoantibodies against type I IFNs and predisposition to viral diseases. © 2023, The Author(s).

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Style	Citing Format
MLA	Le Voyer T, et al.. "Autoantibodies Against Type I Ifns in Humans With Alternative Nf-Κb Pathway Deficiency." Nature, vol. 623, no. 7988, 2023, pp. 803-813.
APA	Le Voyer T, Parent AV, Liu X, Cederholm A, Gervais A, Rosain J, Nguyen T, Perez Lorenzo M, Rackaityte E, Rinchai D, Zhang P, Bizien L, Hancioglu G, Ghillanidalbin P, Charuel JL, Philippot Q, Gueye MS, Maglorius Renkilaraj MRL, Ogishi M, ... Puel A (2023). Autoantibodies Against Type I Ifns in Humans With Alternative Nf-Κb Pathway Deficiency. Nature, 623(7988), 803-813.
Chicago	Le Voyer T, Parent AV, Liu X, Cederholm A, Gervais A, Rosain J, Nguyen T, et al.. "Autoantibodies Against Type I Ifns in Humans With Alternative Nf-Κb Pathway Deficiency." Nature 623, no. 7988 (2023): 803-813.
Harvard	Le Voyer T et al. (2023) 'Autoantibodies Against Type I Ifns in Humans With Alternative Nf-Κb Pathway Deficiency', Nature, 623(7988), pp. 803-813.
Vancouver	Le Voyer T, Parent AV, Liu X, Cederholm A, Gervais A, Rosain J, et al.. Autoantibodies Against Type I Ifns in Humans With Alternative Nf-Κb Pathway Deficiency. Nature. 2023;623(7988):803-813.
BibTex	@article{ author = {Le Voyer T and Parent AV and Liu X and Cederholm A and Gervais A and Rosain J and Nguyen T and Perez Lorenzo M and Rackaityte E and Rinchai D and Zhang P and Bizien L and Hancioglu G and Ghillanidalbin P and Charuel JL and Philippot Q and Gueye MS and Maglorius Renkilaraj MRL and Ogishi M and Soudee C and Migaud M and Rozenberg F and Momenilandi M and Riller Q and Imberti L and Delmonte OM and Muller G and Keller B and Orrego J and Franco Gallego WA and Rubin T and Emiroglu M and Parvaneh N and Eriksson D and Arandaguillen M and Berrios DI and Vong L and Katelaris CH and Mustillo P and Raedler J and Bohlen J and Bengi Celik J and Astudillo C and Winter S and Boissondupuis S and Oksenhendler E and Okada S and Caluseriu O and Ursini MV and Ballot E and Lafarge G and Freiberger T and Arangofranco CA and Levy R and Aiuti A and Almuhsen S and Almulla F and Andreakos E and Arias AA and Feldman HB and Bastard P and Bondarenko A and Borghesi A and Bousfiha AA and Brodin P and Bryceson Y and Casari G and Christodoulou J and Colobran R and Condinoneto A and Fellay J and Flores C and Franco JL and Haerynck F and Halwani R and Hammarstrom L and Heath JR and Hsieh EWY and Itan Y and Kaja E and Kisand K and Ku CL and Ling Y and Lau YL and Mansouri D and Meyts I and Milner JD and Mogensen TH and Novelli A and Novelli G and Okamoto K and Ozcelik T and De Diego RP and Pereztur J and Perlin DS and Prando C and Pujol A and Quintanamurci L and Renia L and Resnick I and Rodriguezgallego C and Sanchoshimizu V and Sediva A and Seppanen MRJ and Shahrooei M and Shcherbina A and Palacin PS and Pesole G and Spaan AN and Su HC and Tancevski I and Tayoun AA and Amara A and Gorochov G and Temel SG and Thorball C and Tiberghien P and Trouillet Assant S and Turvey S and Uddin KMF and Uddin MJ and Van De Beek D and Vidigal M and Vinh DC and Von Bernuth H and Wauters J and Zatz M and Zhang SY and Ng LFP and Mclean C and Guffroy A and Derisi JL and Yu D and Miller C and Feng Y and Guichard A and Beziat V and Bustamante J and Panhammarstrom Q and Zhang Y and Rosen LB and Holland SM and Bosticardo M and Kenney H and Castagnoli R and Slade CA and Boztug K and Mahlaoui N and Latour S and Abraham RS and Lougaris V and Hauck F and Atschekzei F and Sogkas G and Poli MC and Slatter MA and Palterer B and Keller MD and Pinzoncharry A and Sullivan A and Droney L and Suan D and Wong M and Kane A and Hu H and Ma C and Grombirikova H and Ciznar P and Dalal I and Aladjidi N and Hie M and Lazaro E and Keles S and Malphettes M and Pasquet M and Maccari ME and Meinhardt A and Ikinciogullari A and Shahrooei M and Celmeli F and Frosk P and Goodnow CC and Gray PE and Belot A and Kuehn HS and Rosenzweig SD and Miyara M and Licciardi F and Servettaz A and Barlogis V and Le Guenno G and Herrmann VM and Kuijpers T and Ducoux G and Sarrotreynauld F and Schuetz C and Cunninghamrundles C and Rieuxlaucat F and Tangye SG and Sobacchi C and Doffinger R and Warnatz K and Grimbacher B and Fieschi C and Berteloot L and Bryant VL and Neven B and Abel L and Zhang Q and Boisson B and Cobat A and Jouanguy E and Kampe O and Roifman CM and Landegren N and Notarangelo LD and Anderson MS and Casanova JL and Puel A}, title = {Autoantibodies Against Type I Ifns in Humans With Alternative Nf-Κb Pathway Deficiency}, journal = {Nature}, volume = {623}, number = {7988}, pages = {803-813}, year = {2023} }
RIS	TY - JOUR AU - Le Voyer T AU - Parent AV AU - Liu X AU - Cederholm A AU - Gervais A AU - Rosain J AU - Nguyen T AU - Perez Lorenzo M AU - Rackaityte E AU - Rinchai D AU - Zhang P AU - Bizien L AU - Hancioglu G AU - Ghillanidalbin P AU - Charuel JL AU - Philippot Q AU - Gueye MS AU - Maglorius Renkilaraj MRL AU - Ogishi M AU - Soudee C AU - Migaud M AU - Rozenberg F AU - Momenilandi M AU - Riller Q AU - Imberti L AU - Delmonte OM AU - Muller G AU - Keller B AU - Orrego J AU - Franco Gallego WA AU - Rubin T AU - Emiroglu M AU - Parvaneh N AU - Eriksson D AU - Arandaguillen M AU - Berrios DI AU - Vong L AU - Katelaris CH AU - Mustillo P AU - Raedler J AU - Bohlen J AU - Bengi Celik J AU - Astudillo C AU - Winter S AU - Boissondupuis S AU - Oksenhendler E AU - Okada S AU - Caluseriu O AU - Ursini MV AU - Ballot E AU - Lafarge G AU - Freiberger T AU - Arangofranco CA AU - Levy R AU - Aiuti A AU - Almuhsen S AU - Almulla F AU - Andreakos E AU - Arias AA AU - Feldman HB AU - Bastard P AU - Bondarenko A AU - Borghesi A AU - Bousfiha AA AU - Brodin P AU - Bryceson Y AU - Casari G AU - Christodoulou J AU - Colobran R AU - Condinoneto A AU - Fellay J AU - Flores C AU - Franco JL AU - Haerynck F AU - Halwani R AU - Hammarstrom L AU - Heath JR AU - Hsieh EWY AU - Itan Y AU - Kaja E AU - Kisand K AU - Ku CL AU - Ling Y AU - Lau YL AU - Mansouri D AU - Meyts I AU - Milner JD AU - Mogensen TH AU - Novelli A AU - Novelli G AU - Okamoto K AU - Ozcelik T AU - De Diego RP AU - Pereztur J AU - Perlin DS AU - Prando C AU - Pujol A AU - Quintanamurci L AU - Renia L AU - Resnick I AU - Rodriguezgallego C AU - Sanchoshimizu V AU - Sediva A AU - Seppanen MRJ AU - Shahrooei M AU - Shcherbina A AU - Palacin PS AU - Pesole G AU - Spaan AN AU - Su HC AU - Tancevski I AU - Tayoun AA AU - Amara A AU - Gorochov G AU - Temel SG AU - Thorball C AU - Tiberghien P AU - Trouillet Assant S AU - Turvey S AU - Uddin KMF AU - Uddin MJ AU - Van De Beek D AU - Vidigal M AU - Vinh DC AU - Von Bernuth H AU - Wauters J AU - Zatz M AU - Zhang SY AU - Ng LFP AU - Mclean C AU - Guffroy A AU - Derisi JL AU - Yu D AU - Miller C AU - Feng Y AU - Guichard A AU - Beziat V AU - Bustamante J AU - Panhammarstrom Q AU - Zhang Y AU - Rosen LB AU - Holland SM AU - Bosticardo M AU - Kenney H AU - Castagnoli R AU - Slade CA AU - Boztug K AU - Mahlaoui N AU - Latour S AU - Abraham RS AU - Lougaris V AU - Hauck F AU - Atschekzei F AU - Sogkas G AU - Poli MC AU - Slatter MA AU - Palterer B AU - Keller MD AU - Pinzoncharry A AU - Sullivan A AU - Droney L AU - Suan D AU - Wong M AU - Kane A AU - Hu H AU - Ma C AU - Grombirikova H AU - Ciznar P AU - Dalal I AU - Aladjidi N AU - Hie M AU - Lazaro E AU - Keles S AU - Malphettes M AU - Pasquet M AU - Maccari ME AU - Meinhardt A AU - Ikinciogullari A AU - Shahrooei M AU - Celmeli F AU - Frosk P AU - Goodnow CC AU - Gray PE AU - Belot A AU - Kuehn HS AU - Rosenzweig SD AU - Miyara M AU - Licciardi F AU - Servettaz A AU - Barlogis V AU - Le Guenno G AU - Herrmann VM AU - Kuijpers T AU - Ducoux G AU - Sarrotreynauld F AU - Schuetz C AU - Cunninghamrundles C AU - Rieuxlaucat F AU - Tangye SG AU - Sobacchi C AU - Doffinger R AU - Warnatz K AU - Grimbacher B AU - Fieschi C AU - Berteloot L AU - Bryant VL AU - Neven B AU - Abel L AU - Zhang Q AU - Boisson B AU - Cobat A AU - Jouanguy E AU - Kampe O AU - Roifman CM AU - Landegren N AU - Notarangelo LD AU - Anderson MS AU - Casanova JL AU - Puel A TI - Autoantibodies Against Type I Ifns in Humans With Alternative Nf-Κb Pathway Deficiency JO - Nature VL - 623 IS - 7988 SP - 803 EP - 813 PY - 2023 ER -

Style

Citing Format

MLA

Le Voyer T, et al.. "Autoantibodies Against Type I Ifns in Humans With Alternative Nf-Κb Pathway Deficiency." Nature, vol. 623, no. 7988, 2023, pp. 803-813.

APA

Le Voyer T, Parent AV, Liu X, Cederholm A, Gervais A, Rosain J, Nguyen T, Perez Lorenzo M, Rackaityte E, Rinchai D, Zhang P, Bizien L, Hancioglu G, Ghillanidalbin P, Charuel JL, Philippot Q, Gueye MS, Maglorius Renkilaraj MRL, Ogishi M, ... Puel A (2023). Autoantibodies Against Type I Ifns in Humans With Alternative Nf-Κb Pathway Deficiency. Nature, 623(7988), 803-813.

Chicago

Le Voyer T, Parent AV, Liu X, Cederholm A, Gervais A, Rosain J, Nguyen T, et al.. "Autoantibodies Against Type I Ifns in Humans With Alternative Nf-Κb Pathway Deficiency." Nature 623, no. 7988 (2023): 803-813.

Harvard

Le Voyer T et al. (2023) 'Autoantibodies Against Type I Ifns in Humans With Alternative Nf-Κb Pathway Deficiency', Nature, 623(7988), pp. 803-813.

Vancouver

Le Voyer T, Parent AV, Liu X, Cederholm A, Gervais A, Rosain J, et al.. Autoantibodies Against Type I Ifns in Humans With Alternative Nf-Κb Pathway Deficiency. Nature. 2023;623(7988):803-813.

BibTex

@article{ author = {Le Voyer T and Parent AV and Liu X and Cederholm A and Gervais A and Rosain J and Nguyen T and Perez Lorenzo M and Rackaityte E and Rinchai D and Zhang P and Bizien L and Hancioglu G and Ghillanidalbin P and Charuel JL and Philippot Q and Gueye MS and Maglorius Renkilaraj MRL and Ogishi M and Soudee C and Migaud M and Rozenberg F and Momenilandi M and Riller Q and Imberti L and Delmonte OM and Muller G and Keller B and Orrego J and Franco Gallego WA and Rubin T and Emiroglu M and Parvaneh N and Eriksson D and Arandaguillen M and Berrios DI and Vong L and Katelaris CH and Mustillo P and Raedler J and Bohlen J and Bengi Celik J and Astudillo C and Winter S and Boissondupuis S and Oksenhendler E and Okada S and Caluseriu O and Ursini MV and Ballot E and Lafarge G and Freiberger T and Arangofranco CA and Levy R and Aiuti A and Almuhsen S and Almulla F and Andreakos E and Arias AA and Feldman HB and Bastard P and Bondarenko A and Borghesi A and Bousfiha AA and Brodin P and Bryceson Y and Casari G and Christodoulou J and Colobran R and Condinoneto A and Fellay J and Flores C and Franco JL and Haerynck F and Halwani R and Hammarstrom L and Heath JR and Hsieh EWY and Itan Y and Kaja E and Kisand K and Ku CL and Ling Y and Lau YL and Mansouri D and Meyts I and Milner JD and Mogensen TH and Novelli A and Novelli G and Okamoto K and Ozcelik T and De Diego RP and Pereztur J and Perlin DS and Prando C and Pujol A and Quintanamurci L and Renia L and Resnick I and Rodriguezgallego C and Sanchoshimizu V and Sediva A and Seppanen MRJ and Shahrooei M and Shcherbina A and Palacin PS and Pesole G and Spaan AN and Su HC and Tancevski I and Tayoun AA and Amara A and Gorochov G and Temel SG and Thorball C and Tiberghien P and Trouillet Assant S and Turvey S and Uddin KMF and Uddin MJ and Van De Beek D and Vidigal M and Vinh DC and Von Bernuth H and Wauters J and Zatz M and Zhang SY and Ng LFP and Mclean C and Guffroy A and Derisi JL and Yu D and Miller C and Feng Y and Guichard A and Beziat V and Bustamante J and Panhammarstrom Q and Zhang Y and Rosen LB and Holland SM and Bosticardo M and Kenney H and Castagnoli R and Slade CA and Boztug K and Mahlaoui N and Latour S and Abraham RS and Lougaris V and Hauck F and Atschekzei F and Sogkas G and Poli MC and Slatter MA and Palterer B and Keller MD and Pinzoncharry A and Sullivan A and Droney L and Suan D and Wong M and Kane A and Hu H and Ma C and Grombirikova H and Ciznar P and Dalal I and Aladjidi N and Hie M and Lazaro E and Keles S and Malphettes M and Pasquet M and Maccari ME and Meinhardt A and Ikinciogullari A and Shahrooei M and Celmeli F and Frosk P and Goodnow CC and Gray PE and Belot A and Kuehn HS and Rosenzweig SD and Miyara M and Licciardi F and Servettaz A and Barlogis V and Le Guenno G and Herrmann VM and Kuijpers T and Ducoux G and Sarrotreynauld F and Schuetz C and Cunninghamrundles C and Rieuxlaucat F and Tangye SG and Sobacchi C and Doffinger R and Warnatz K and Grimbacher B and Fieschi C and Berteloot L and Bryant VL and Neven B and Abel L and Zhang Q and Boisson B and Cobat A and Jouanguy E and Kampe O and Roifman CM and Landegren N and Notarangelo LD and Anderson MS and Casanova JL and Puel A}, title = {Autoantibodies Against Type I Ifns in Humans With Alternative Nf-Κb Pathway Deficiency}, journal = {Nature}, volume = {623}, number = {7988}, pages = {803-813}, year = {2023} }

RIS

TY - JOUR
AU - Le Voyer T
AU - Parent AV
AU - Liu X
AU - Cederholm A
AU - Gervais A
AU - Rosain J
AU - Nguyen T
AU - Perez Lorenzo M
AU - Rackaityte E
AU - Rinchai D
AU - Zhang P
AU - Bizien L
AU - Hancioglu G
AU - Ghillanidalbin P
AU - Charuel JL
AU - Philippot Q
AU - Gueye MS
AU - Maglorius Renkilaraj MRL
AU - Ogishi M
AU - Soudee C
AU - Migaud M
AU - Rozenberg F
AU - Momenilandi M
AU - Riller Q
AU - Imberti L
AU - Delmonte OM
AU - Muller G
AU - Keller B
AU - Orrego J
AU - Franco Gallego WA
AU - Rubin T
AU - Emiroglu M
AU - Parvaneh N
AU - Eriksson D
AU - Arandaguillen M
AU - Berrios DI
AU - Vong L
AU - Katelaris CH
AU - Mustillo P
AU - Raedler J
AU - Bohlen J
AU - Bengi Celik J
AU - Astudillo C
AU - Winter S
AU - Boissondupuis S
AU - Oksenhendler E
AU - Okada S
AU - Caluseriu O
AU - Ursini MV
AU - Ballot E
AU - Lafarge G
AU - Freiberger T
AU - Arangofranco CA
AU - Levy R
AU - Aiuti A
AU - Almuhsen S
AU - Almulla F
AU - Andreakos E
AU - Arias AA
AU - Feldman HB
AU - Bastard P
AU - Bondarenko A
AU - Borghesi A
AU - Bousfiha AA
AU - Brodin P
AU - Bryceson Y
AU - Casari G
AU - Christodoulou J
AU - Colobran R
AU - Condinoneto A
AU - Fellay J
AU - Flores C
AU - Franco JL
AU - Haerynck F
AU - Halwani R
AU - Hammarstrom L
AU - Heath JR
AU - Hsieh EWY
AU - Itan Y
AU - Kaja E
AU - Kisand K
AU - Ku CL
AU - Ling Y
AU - Lau YL
AU - Mansouri D
AU - Meyts I
AU - Milner JD
AU - Mogensen TH
AU - Novelli A
AU - Novelli G
AU - Okamoto K
AU - Ozcelik T
AU - De Diego RP
AU - Pereztur J
AU - Perlin DS
AU - Prando C
AU - Pujol A
AU - Quintanamurci L
AU - Renia L
AU - Resnick I
AU - Rodriguezgallego C
AU - Sanchoshimizu V
AU - Sediva A
AU - Seppanen MRJ
AU - Shahrooei M
AU - Shcherbina A
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TI - Autoantibodies Against Type I Ifns in Humans With Alternative Nf-Κb Pathway Deficiency
JO - Nature
VL - 623
IS - 7988
SP - 803
EP - 813
PY - 2023
ER -

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Abstract