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Copper-Catalyzed Efficient Synthesis of 5-Arylindazolo[3,2-B]Quinazolin-7(5H)-Ones From 2-Nitrobenzaldehydes Publisher



Arasteh Fard Z1 ; Dilmaghani KA1 ; Soheilizad M2 ; Larijani B3 ; Mahdavi M3
Authors

Source: Tetrahedron Published:2018


Abstract

A novel and practical copper-catalyzed approach was developed for the preparation of 5-arylindazolo[3,2-b]quinazolin-7(5H)-ones. The 2-amino-N′-arylbenzohydrazideis easily prepared by a reaction of isatoic anhydride with arylhydrazine. Then, through a condensation/intramolecular cyclization reaction by 2-nitrobenzaldehydes in the present of CuI, the corresponding 5-arylindazolo[3,2-b]quinazolin-7(5H)-ones are produced in good yields. © 2018
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