Green Synthesis of 2-((2-Aryl-3-Oxoisoindolin-1-Yl)Methyl)Quinazolin-4(3H)-Ones Via Sequential Condensation, Sp3 C

Green Synthesis of 2-((2-Aryl-3-Oxoisoindolin-1-Yl)Methyl)Quinazolin-4(3H)-Ones Via Sequential Condensation, Sp3 C–H Bond Functionalization and Cyclization Publisher

Tashrifi Z¹ ; Radmoghadam K¹ ; Mehrdad M¹ ; Soheilizad M² ; Larijani B³ ; Mahdavi M³

Show Affiliations

1. Department of Chemistry, University of Guilan, Rasht PO Box 41335-1914, Iran
2. CinnaGen Medical Biotechnology Research Center, Alborz University of Medical Sciences, Karaj, Iran
3. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran

Source: Tetrahedron Letters Published:2018

Abstract

A novel and green synthesis of 2-((2-aryl-3-oxoisoindolin-1-yl)methyl)quinazolin-4(3H)-one is described. The one-pot three-component reaction between 2-methylquinazolin-4(3H)-ones, aryl amines and 2-formylbenzoic acid, through a sequential condensation, sp3 C–H bond functionalization and cyclization reactions in aqueous media leads to formation of desired compounds in good to excellent yields. © 2018 Elsevier Ltd

Style	Citing Format
MLA	Tashrifi Z, et al.. "Green Synthesis of 2-((2-Aryl-3-Oxoisoindolin-1-Yl)Methyl)Quinazolin-4(3H)-Ones Via Sequential Condensation, Sp3 C–H Bond Functionalization and Cyclization." Tetrahedron Letters, vol. 59, no. 16, 2018, pp. 1555-1559.
APA	Tashrifi Z, Radmoghadam K, Mehrdad M, Soheilizad M, Larijani B, Mahdavi M (2018). Green Synthesis of 2-((2-Aryl-3-Oxoisoindolin-1-Yl)Methyl)Quinazolin-4(3H)-Ones Via Sequential Condensation, Sp3 C–H Bond Functionalization and Cyclization. Tetrahedron Letters, 59(16), 1555-1559.
Chicago	Tashrifi Z, Radmoghadam K, Mehrdad M, Soheilizad M, Larijani B, Mahdavi M. "Green Synthesis of 2-((2-Aryl-3-Oxoisoindolin-1-Yl)Methyl)Quinazolin-4(3H)-Ones Via Sequential Condensation, Sp3 C–H Bond Functionalization and Cyclization." Tetrahedron Letters 59, no. 16 (2018): 1555-1559.
Harvard	Tashrifi Z et al. (2018) 'Green Synthesis of 2-((2-Aryl-3-Oxoisoindolin-1-Yl)Methyl)Quinazolin-4(3H)-Ones Via Sequential Condensation, Sp3 C–H Bond Functionalization and Cyclization', Tetrahedron Letters, 59(16), pp. 1555-1559.
Vancouver	Tashrifi Z, Radmoghadam K, Mehrdad M, Soheilizad M, Larijani B, Mahdavi M. Green Synthesis of 2-((2-Aryl-3-Oxoisoindolin-1-Yl)Methyl)Quinazolin-4(3H)-Ones Via Sequential Condensation, Sp3 C–H Bond Functionalization and Cyclization. Tetrahedron Letters. 2018;59(16):1555-1559.
BibTex	@article{ author = {Tashrifi Z and Radmoghadam K and Mehrdad M and Soheilizad M and Larijani B and Mahdavi M}, title = {Green Synthesis of 2-((2-Aryl-3-Oxoisoindolin-1-Yl)Methyl)Quinazolin-4(3H)-Ones Via Sequential Condensation, Sp3 C–H Bond Functionalization and Cyclization}, journal = {Tetrahedron Letters}, volume = {59}, number = {16}, pages = {1555-1559}, year = {2018} }
RIS	TY - JOUR AU - Tashrifi Z AU - Radmoghadam K AU - Mehrdad M AU - Soheilizad M AU - Larijani B AU - Mahdavi M TI - Green Synthesis of 2-((2-Aryl-3-Oxoisoindolin-1-Yl)Methyl)Quinazolin-4(3H)-Ones Via Sequential Condensation, Sp3 C–H Bond Functionalization and Cyclization JO - Tetrahedron Letters VL - 59 IS - 16 SP - 1555 EP - 1559 PY - 2018 ER -

Science Communicator Platform

Authors

Authors Affiliations

Abstract